Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed in immortal mammalian cells
Platt, K.L., Edenharder, R., Aderhold, S., Muckel, E., Glatt, H.
Published in Mutation research (21.12.2010)
Published in Mutation research (21.12.2010)
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CRYOPRESERVED PRIMARY HEPATOCYTES AS A CONSTANTLY AVAILABLE IN VITRO MODEL FOR THE EVALUATION OF HUMAN AND ANIMAL DRUG METABOLISM AND ENZYME INDUCTION
HENGSTLER, JAN G., UTESCH, D., STEINBERG, P., PLATT, K. L., DIENER, B., RINGEL, M., SWALES, N., FISCHER, T., BIEFANG, K., GERL, M., BÖTTGER, T., OESCH, F.
Published in Drug metabolism reviews (01.01.2000)
Published in Drug metabolism reviews (01.01.2000)
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Effects of an acute exposure to toluene on the DNA repair activity of the human 8-oxoguanine DNA glycosylase 1 (hOGG1) in healthy subjects
Finkenwirth, P, Spelmeyer, U, Hommel, G, Rose, D.-M, Jung, D, Roßbach, B, Mayer-Popken, O, Platt, K.-L, Oesch, F, Muttray, A
Published in Archives of toxicology (01.08.2009)
Published in Archives of toxicology (01.08.2009)
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Drug Metabolizing Capacity of Cryopreserved Human, Rat, and Mouse Liver Parenchymal Cells in Suspension
STEINBERG, P, FISCHER, T, KIULIES, S, BIEFANG, K, PLATT, K.-L, OESCH, F, BÖTTGER, T, BULITTA, C, KEMPF, P, HENGSTLER, J
Published in Drug metabolism and disposition (01.12.1999)
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Published in Drug metabolism and disposition (01.12.1999)
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Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in metabolically competent V79 cells
Edenharder, R, Sager, J.W, Glatt, H, Muckel, E, Platt, K.L
Published in Mutation research (26.11.2002)
Published in Mutation research (26.11.2002)
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Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7
Ralston, S L, Seidel, A, Luch, A, Platt, K L, Baird, W M
Published in Carcinogenesis (New York) (01.12.1995)
Published in Carcinogenesis (New York) (01.12.1995)
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Synthesis and mutagenicity of the diastereomeric fjord-region 11,12-dihydrodiol 13,14-epoxides of dibenzo[a,l]pyrene
Luch, A, Glatt, H, Platt, K L, Oesch, F, Seidel, A
Published in Carcinogenesis (New York) (01.11.1994)
Published in Carcinogenesis (New York) (01.11.1994)
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The potent carcinogen dibenzo[a,l]pyrene is metabolically activated to fjord-region 11,12-diol 13,14-epoxides in human mammary carcinoma MCF-7 cell cultures
RALSTON, S. L, LAU, H. H. S, SEIDEL, A, LUCH, A, PLATT, K. L, BAIRD, W. M
Published in Cancer research (Chicago, Ill.) (15.02.1994)
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Published in Cancer research (Chicago, Ill.) (15.02.1994)
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Stereoselective Activation of Dibenzo[a,l]pyrene and Its trans-11,12-Dihydrodiol to Fjord Region 11,12-Diol 13,14-Epoxides in a Human Mammary Carcinoma MCF-7 Cell-Mediated V79 Cell Mutation Assay
Ralston, Sherry L, Coffing, Stephanie L, Seidel, Albrecht, Luch, Andreas, Platt, Karl-Ludwig, Baird, William M
Published in Chemical research in toxicology (01.06.1997)
Published in Chemical research in toxicology (01.06.1997)
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Conjugation of anti-dihydrodiol epoxides of benzo[ a]pyrene, chrysene, benzo[ c]phenanthrene and dibenz[ a, h]anthracene with glutathione catalyzed by cytosol and by the Mu-class glutathione transferase HTP II from rat liver
Funk, M., Gath, I., Seidel, A., Oesch, F., Platt, K.L.
Published in Chemico-biological interactions (30.03.1995)
Published in Chemico-biological interactions (30.03.1995)
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