Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1
Barrow, James C., Rittle, Kenneth E., Ngo, Phung L., Selnick, Harold G., Graham, Samuel L., Pitzenberger, Steven M., McGaughey, Georgia B., Colussi, Dennis, Lai, Ming-Tain, Huang, Qian, Tugusheva, Katherine, Espeseth, Amy S., Simon, Adam J., Munshi, Sanjeev K., Vacca, Joseph P.
Published in ChemMedChem (09.07.2007)
Published in ChemMedChem (09.07.2007)
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Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Egbertson, Melissa, McGaughey, Georgia B., Pitzenberger, Steven M., Stauffer, Shaun R., Coburn, Craig A., Stachel, Shawn J., Yang, Wenjin, Barrow, James C., Neilson, Lou Anne, McWherter, Melody, Perlow, Debra, Fahr, Bruce, Munshi, Sanjeev, Allison, Timothy J., Holloway, Katharine, Selnick, Harold G., Yang, ZhiQiang, Swestock, John, Simon, Adam J., Sankaranarayanan, Sethu, Colussi, Dennis, Tugusheva, Katherine, Lai, Ming-Tain, Pietrak, Beth, Haugabook, Shari, Jin, Lixia, Chen, I.-W., Holahan, Marie, Stranieri-Michener, Maria, Cook, Jacquelynn J., Vacca, Joseph, Graham, Samuel L.
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
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Martinelline and Martinellic Acid, Novel G-Protein Linked Receptor Antagonists from the Tropical Plant Martinella iquitosensis (Bignoniaceae)
Witherup, Keith M, Ransom, Richard W, Graham, Amy C, Bernard, Aurora M, Salvatore, Michael J, Lumma, William C, Anderson, Paul S, Pitzenberger, Steven M, Varga, Sandor L
Published in Journal of the American Chemical Society (01.06.1995)
Published in Journal of the American Chemical Society (01.06.1995)
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Mechanism of the solution oxidation of rofecoxib under alkaline conditions
Harmon, Paul A, Biffar, Stephen, Pitzenberger, Steven M, Reed, Robert A
Published in Pharmaceutical research (01.10.2005)
Published in Pharmaceutical research (01.10.2005)
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Transglutaminase Inhibition by 2-[(2-Oxopropyl)thio]imidazolium Derivatives: Mechanism of Factor XIIIa Inactivation
Freund, Kurt F, Doshi, Kundan P, Gaul, Stanley L, Claremon, David A, Remy, David C, Baldwin, John J, Pitzenberger, Steven M, Stern, Andrew M
Published in Biochemistry (Easton) (01.08.1994)
Published in Biochemistry (Easton) (01.08.1994)
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Solution structure of the cytoplasmic domain of phospholamban: phosphorylation leads to a local perturbation in secondary structure
Mortishire-Smith, Russell J, Pitzenberger, Steven M, Burke, Carl J, Middaugh, C. Russell, Garsky, Victor M, Johnson, Robert G
Published in Biochemistry (Easton) (13.06.1995)
Published in Biochemistry (Easton) (13.06.1995)
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BIOACTIVATION OF THE 3-AMINO-6-CHLOROPYRAZINONE RING IN A THROMBIN INHIBITOR LEADS TO NOVEL DIHYDRO-IMIDAZOLE AND IMIDAZOLIDINE DERIVATIVES: STRUCTURES AND MECHANISM USING 13C-LABELS, MASS SPECTROMETRY, AND NMR
SUBRAMANIAN, Raju, LIN, Charles C, HO, Jonathan Z, PITZENBERGER, Steven M, SILVA-ELIPE, Maria V, GIBSON, Christopher R, BRAUN, Matthew P, XIAO YU, YERGEY, James L, SINGH, Rominder
Published in Drug metabolism and disposition (01.11.2003)
Published in Drug metabolism and disposition (01.11.2003)
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Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels
Ma, Decheng, Wasylaschuk, Walter R, Beasley, Christopher, Zhao, Zhongxi (Zack), Harmon, Paul A, Ballard, John M, Pitzenberger, Steven M, Varga, Sandor L, Reed, Robert A
Published in Journal of pharmaceutical and biomedical analysis (29.06.2004)
Published in Journal of pharmaceutical and biomedical analysis (29.06.2004)
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Journal Article
Complestatin to chloropeptin I via a quantitative acid catalyzed rearrangement. Absolute stereochemical determination of complestatin
Jayasuriya, Hiranthi, Salituro, Gino M., Smith, Scott K., Heck, James V., Gould, Steven J., Singh, Sheo B., Homnick, Carl F., Holloway, M.Katharine, Pitzenberger, Steven M., Patane, Michael A.
Published in Tetrahedron letters (16.04.1998)
Published in Tetrahedron letters (16.04.1998)
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Journal Article
Antibacterial Activity of Lonchocarpol A
Salvatore, Michael J, King, Aurora B, Graham, Amy C, Onishi, H. Russell, Bartizal, Kenneth F, Abruzzo, George K, Gill, Charles J, Ramjit, Harri G, Pitzenberger, Steven M, Witherup, Keith M
Published in Journal of natural products (Washington, D.C.) (01.05.1998)
Published in Journal of natural products (Washington, D.C.) (01.05.1998)
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Journal Article
Proton NMR assignments and secondary structure of the snake venom protein echistatin
Chen, Yuan, Pitzenberger, Steven M, Garsky, Victor M, Lumma, Patricia K, Sanyal, Gautam, Baum, Jean
Published in Biochemistry (Easton) (17.12.1991)
Published in Biochemistry (Easton) (17.12.1991)
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Infrared spectroscopy of matrix-isolated propadienone
Chapman, Orville L, Miller, Michael D, Pitzenberger, Steven M
Published in Journal of the American Chemical Society (01.10.1987)
Published in Journal of the American Chemical Society (01.10.1987)
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Journal Article
An unusual dimer of 2-mercaptothiophene
Ponticello, Gerald S, Habecker, Charles N, Varga, Sandor L, Pitzenberger, Steven M
Published in Journal of organic chemistry (01.06.1989)
Published in Journal of organic chemistry (01.06.1989)
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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs
Hartman, George D, Halczenko, Wasyl, Duggan, Mark E, Imagire, Jill S, Smith, Robert L, Pitzenberger, Steven M, Fitzpatrick, Susan L, Alberts, Alfred W, Bostedor, Rick
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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Journal Article
High Fatty Acid Content in Rabbit Serum Is Responsible for the Differentiation of Osteoblasts Into Adipocyte‐like Cells
Diascro, Dominic D., Vogel, Robert L., Johnson, Timothy E., Witherup, Keith M., Pitzenberger, Steven M., Rutledge, Su Jane, Prescott, David J., Rodan, Gideon A., Schmidt, Azriel
Published in Journal of bone and mineral research (01.01.1998)
Published in Journal of bone and mineral research (01.01.1998)
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