Roles of lysophosphatidic acid and sphingosine-1-phosphate in stem cell biology
Lidgerwood, Grace E., Pitson, Stuart M., Bonder, Claudine, Pébay, Alice
Published in Progress in lipid research (01.10.2018)
Published in Progress in lipid research (01.10.2018)
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Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion
Duszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G., Yap, Alpha S.
Published in Current biology (22.03.2021)
Published in Current biology (22.03.2021)
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Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia
Nwosu, Gus O., Ross, David M., Powell, Jason A., Pitson, Stuart M.
Published in Cell death & disease (12.06.2024)
Published in Cell death & disease (12.06.2024)
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Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells
McNaughton, Melissa, Pitman, Melissa, Pitson, Stuart M, Pyne, Nigel J, Pyne, Susan
Published in Oncotarget (29.03.2016)
Published in Oncotarget (29.03.2016)
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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia
Powell, Jason A., Lewis, Alexander C., Zhu, Wenying, Toubia, John, Pitman, Melissa R., Wallington-Beddoe, Craig T., Moretti, Paul A.B., Iarossi, Diana, Samaraweera, Saumya E., Cummings, Nik, Ramshaw, Hayley S., Thomas, Daniel, Wei, Andrew H., Lopez, Angel F., D'Andrea, Richard J., Lewis, Ian D., Pitson, Stuart M.
Published in Blood (09.02.2017)
Published in Blood (09.02.2017)
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FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
Tonelli, Francesca, Lim, Keng Gat, Loveridge, Carolyn, Long, Jaclyn, Pitson, Stuart M., Tigyi, Gabor, Bittman, Robert, Pyne, Susan, Pyne, Nigel J.
Published in Cellular signalling (01.10.2010)
Published in Cellular signalling (01.10.2010)
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A Drug Screening Pipeline Using 2D and 3D Patient-Derived In Vitro Models for Pre-Clinical Analysis of Therapy Response in Glioblastoma
Lenin, Sakthi, Ponthier, Elise, Scheer, Kaitlin G, Yeo, Erica C F, Tea, Melinda N, Ebert, Lisa M, Oksdath Mansilla, Mariana, Poonnoose, Santosh, Baumgartner, Ulrich, Day, Bryan W, Ormsby, Rebecca J, Pitson, Stuart M, Gomez, Guillermo A
Published in International journal of molecular sciences (21.04.2021)
Published in International journal of molecular sciences (21.04.2021)
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Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet―Fed Mice
BRUCE, Clinton R, RISIS, Steve, MEIKLE, Peter J, PITSON, Stuart M, FEBBRAIO, Mark A, BABB, Joanne R, YANG, Christine, KOWALSKI, Greg M, SELATHURAI, Ahrathy, LEE-YOUNG, Robert S, WEIR, Jacquelyn M, YOSHIOKA, Kazuaki, TAKUWA, Yoh
Published in Diabetes (New York, N.Y.) (01.12.2012)
Published in Diabetes (New York, N.Y.) (01.12.2012)
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Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation
Yamane, Daisuke, McGivern, David R, Wauthier, Eliane, Yi, MinKyung, Madden, Victoria J, Welsch, Christoph, Antes, Iris, Wen, Yahong, Chugh, Pauline E, McGee, Charles E, Widman, Douglas G, Misumi, Ichiro, Bandyopadhyay, Sibali, Kim, Seungtaek, Shimakami, Tetsuro, Oikawa, Tsunekazu, Whitmire, Jason K, Heise, Mark T, Dittmer, Dirk P, Kao, C Cheng, Pitson, Stuart M, Merrill, Alfred H, Reid, Lola M, Lemon, Stanley M
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma
Kollis, Paris M, Ebert, Lisa M, Toubia, John, Bastow, Cameron R, Ormsby, Rebecca J, Poonnoose, Santosh I, Lenin, Sakthi, Tea, Melinda N, Pitson, Stuart M, Gomez, Guillermo A, Brown, Michael P, Gargett, Tessa
Published in Frontiers in immunology (06.04.2022)
Published in Frontiers in immunology (06.04.2022)
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The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism
Pitman, Melissa R., Lewis, Alexander C., Davies, Lorena T., Moretti, Paul A. B., Anderson, Dovile, Creek, Darren J., Powell, Jason A., Pitson, Stuart M.
Published in Scientific reports (10.01.2022)
Published in Scientific reports (10.01.2022)
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Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition
Bennett, Melissa K., Li, Manjun, Tea, Melinda N., Pitman, Melissa R., Toubia, John, Wang, Paul P.-S., Anderson, Dovile, Creek, Darren J., Orlowski, Robert Z., Gliddon, Briony L., Powell, Jason A., Wallington-Beddoe, Craig T., Pitson, Stuart M.
Published in Neoplasia (New York, N.Y.) (01.01.2022)
Published in Neoplasia (New York, N.Y.) (01.01.2022)
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Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD
Tran, Hai B, Jersmann, Hubertus, Truong, Tung Thanh, Hamon, Rhys, Roscioli, Eugene, Ween, Miranda, Pitman, Melissa R, Pitson, Stuart M, Hodge, Greg, Reynolds, Paul N, Hodge, Sandra
Published in PloS one (07.11.2017)
Published in PloS one (07.11.2017)
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GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma
Gargett, Tessa, Ebert, Lisa M, Truong, Nga T H, Kollis, Paris M, Sedivakova, Kristyna, Yu, Wenbo, Yeo, Erica C F, Wittwer, Nicole L, Gliddon, Briony L, Tea, Melinda N, Ormsby, Rebecca, Poonnoose, Santosh, Nowicki, Jake, Vittorio, Orazio, Ziegler, David S, Pitson, Stuart M, Brown, Michael P
Published in Journal for immunotherapy of cancer (01.09.2022)
Published in Journal for immunotherapy of cancer (01.09.2022)
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