SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression
Vazquez, M. J., Toro, C. A., Castellano, J. M., Ruiz-Pino, F., Roa, J., Beiroa, D., Heras, V., Velasco, I., Dieguez, C., Pinilla, L., Gaytan, F., Nogueiras, R., Bosch, M. A., Rønnekleiv, O. K., Lomniczi, A., Ojeda, S. R., Tena-Sempere, M.
Published in Nature communications (10.10.2018)
Published in Nature communications (10.10.2018)
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Journal Article
Sex Steroids and the Control of the Kiss1 System: Developmental Roles and Major Regulatory Actions
García-Galiano, D., Pinilla, L., Tena-Sempere, M.
Published in Journal of neuroendocrinology (01.01.2012)
Published in Journal of neuroendocrinology (01.01.2012)
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Journal Article
Conference Proceeding
Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54
Navarro, V. M., Fernández‐Fernández, R., Castellano, J. M., Roa, J., Mayen, A., Barreiro, M. L., Gaytan, F., Aguilar, E., Pinilla, L., Dieguez, C., Tena‐Sempere, M.
Published in The Journal of physiology (01.12.2004)
Published in The Journal of physiology (01.12.2004)
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Journal Article
AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and reproduction
Franssen, D., Barroso, A., Ruiz-Pino, F., Vázquez, M.J., García-Galiano, D., Castellano, J.M., Onieva, R., Ruiz-Cruz, M., Poutanen, M., Gaytán, F., Diéguez, C., Pinilla, L., Lopez, M., Roa, J., Tena-Sempere, M.
Published in Metabolism, clinical and experimental (01.02.2021)
Published in Metabolism, clinical and experimental (01.02.2021)
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Journal Article
Metabolic Programming of Puberty: Sexually Dimorphic Responses to Early Nutritional Challenges
Sánchez-Garrido, M. A, Castellano, J. M, Ruiz-Pino, F, Garcia-Galiano, D, Manfredi-Lozano, M, Leon, S, Romero-Ruiz, A, Diéguez, C, Pinilla, L, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.09.2013)
Published in Endocrinology (Philadelphia) (01.09.2013)
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Journal Article
Critical Roles of Kisspeptins in Female Puberty and Preovulatory Gonadotropin Surges as Revealed by a Novel Antagonist
Pineda, R, Garcia-Galiano, D, Roseweir, A, Romero, M, Sanchez-Garrido, M. A, Ruiz-Pino, F, Morgan, K, Pinilla, L, Millar, R. P, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.02.2010)
Published in Endocrinology (Philadelphia) (01.02.2010)
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Journal Article
Novel signals for the integration of energy balance and reproduction
Fernandez-Fernandez, R., Martini, A.C., Navarro, V.M., Castellano, J.M., Dieguez, C., Aguilar, E., Pinilla, L., Tena-Sempere, M.
Published in Molecular and cellular endocrinology (25.07.2006)
Published in Molecular and cellular endocrinology (25.07.2006)
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Journal Article
The Mammalian Target of Rapamycin as Novel Central Regulator of Puberty Onset via Modulation of Hypothalamic Kiss1 System
Roa, J, Garcia-Galiano, D, Varela, L, Sánchez-Garrido, M. A, Pineda, R, Castellano, J. M, Ruiz-Pino, F, Romero, M, Aguilar, E, López, M, Gaytan, F, Diéguez, C, Pinilla, L, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.11.2009)
Published in Endocrinology (Philadelphia) (01.11.2009)
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Journal Article
Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies
Pineda, R, Garcia-Galiano, D, Sanchez-Garrido, M A, Romero, M, Ruiz-Pino, F, Aguilar, E, Dijcks, F A, Blomenröhr, M, Pinilla, L, van Noort, P I, Tena-Sempere, M
Published in American journal of physiology: endocrinology and metabolism (01.07.2010)
Published in American journal of physiology: endocrinology and metabolism (01.07.2010)
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Journal Article
Regulation of NKB Pathways and Their Roles in the Control of Kiss1 Neurons in the Arcuate Nucleus of the Male Mouse
Navarro, V. M, Gottsch, M. L, Wu, M, García-Galiano, D, Hobbs, S. J, Bosch, M. A, Pinilla, L, Clifton, D. K, Dearth, A, Ronnekleiv, O. K, Braun, R. E, Palmiter, R. D, Tena-Sempere, M, Alreja, M, Steiner, R. A
Published in Endocrinology (Philadelphia) (01.11.2011)
Published in Endocrinology (Philadelphia) (01.11.2011)
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Journal Article
Hydrogen and multiwall carbon nanotubes production by catalytic decomposition of methane: Thermogravimetric analysis and scaling-up of Fe–Mo catalysts
Torres, D., Pinilla, J.L., Lázaro, M.J., Moliner, R., Suelves, I.
Published in International journal of hydrogen energy (06.03.2014)
Published in International journal of hydrogen energy (06.03.2014)
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Journal Article
Changes in Hypothalamic KiSS-1 System and Restoration of Pubertal Activation of the Reproductive Axis by Kisspeptin in Undernutrition
Castellano, J. M, Navarro, V. M, Fernández-Fernández, R, Nogueiras, R, Tovar, S, Roa, J, Vazquez, M. J, Vigo, E, Casanueva, F. F, Aguilar, E, Pinilla, L, Dieguez, C, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.09.2005)
Published in Endocrinology (Philadelphia) (01.09.2005)
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Journal Article
Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome
Romero-Ruiz, A, Skorupskaite, K, Gaytan, F, Torres, E, Perdices-Lopez, C, Mannaerts, B M, Qi, S, Leon, S, Manfredi-Lozano, M, Lopez-Rodriguez, C, Avendaño, M S, Sanchez-Garrido, M A, Vazquez, M J, Pinilla, L, van Duin, M, Kohout, T A, Anderson, R A, Tena-Sempere, M
Published in Human reproduction (Oxford) (01.12.2019)
Published in Human reproduction (Oxford) (01.12.2019)
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Journal Article
Developmental and Hormonally Regulated Messenger Ribonucleic Acid Expression of KiSS-1 and Its Putative Receptor, GPR54, in Rat Hypothalamus and Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide
Navarro, V. M, Castellano, J. M, Fernández-Fernández, R, Barreiro, M. L, Roa, J, Sanchez-Criado, J. E, Aguilar, E, Dieguez, C, Pinilla, L, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.10.2004)
Published in Endocrinology (Philadelphia) (01.10.2004)
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Journal Article
Cellular Distribution, Regulated Expression, and Functional Role of the Anorexigenic Peptide, NUCB2/Nesfatin-1, in the Testis
García-Galiano, D, Pineda, R, Ilhan, T, Castellano, J. M, Ruiz-Pino, F, Sánchez-Garrido, M. A, Vazquez, M. J, Sangiao-Alvarellos, S, Romero-Ruiz, A, Pinilla, L, Diéguez, C, Gaytán, F, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.04.2012)
Published in Endocrinology (Philadelphia) (01.04.2012)
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Journal Article
KiSS-1/kisspeptins and the metabolic control of reproduction: Physiologic roles and putative physiopathological implications
Castellano, J.M., Roa, J., Luque, R.M., Dieguez, C., Aguilar, E., Pinilla, L., Tena-Sempere, M.
Published in Peptides (New York, N.Y. : 1980) (2009)
Published in Peptides (New York, N.Y. : 1980) (2009)
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Journal Article
Effects and Interactions of Tachykinins and Dynorphin on FSH and LH Secretion in Developing and Adult Rats
Ruiz-Pino, F, Garcia-Galiano, D, Manfredi-Lozano, M, Leon, S, Sánchez-Garrido, M. A, Roa, J, Pinilla, L, Navarro, V. M, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.02.2015)
Published in Endocrinology (Philadelphia) (01.02.2015)
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Journal Article
Expression of KiSS-1 in Rat Ovary: Putative Local Regulator of Ovulation?
Castellano, J. M, Gaytan, M, Roa, J, Vigo, E, Navarro, V. M, Bellido, C, Dieguez, C, Aguilar, E, Sánchez-Criado, J. E, Pellicer, A, Pinilla, L, Gaytan, F, Tena-Sempere, M
Published in Endocrinology (Philadelphia) (01.10.2006)
Published in Endocrinology (Philadelphia) (01.10.2006)
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