Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
Daniels, Michael J. D., Rivers-Auty, Jack, Schilling, Tom, Spencer, Nicholas G., Watremez, William, Fasolino, Victoria, Booth, Sophie J., White, Claire S., Baldwin, Alex G., Freeman, Sally, Wong, Raymond, Latta, Clare, Yu, Shi, Jackson, Joshua, Fischer, Nicolas, Koziel, Violette, Pillot, Thierry, Bagnall, James, Allan, Stuart M., Paszek, Pawel, Galea, James, Harte, Michael K., Eder, Claudia, Lawrence, Catherine B., Brough, David
Published in Nature communications (11.08.2016)
Published in Nature communications (11.08.2016)
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Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway
Malaplate-Armand, Catherine, Florent-Béchard, Sabrina, Youssef, Ihsen, Koziel, Violette, Sponne, Isabelle, Kriem, Badreddine, Leininger-Muller, Brigitte, Olivier, Jean-Luc, Oster, Thierry, Pillot, Thierry
Published in Neurobiology of disease (01.07.2006)
Published in Neurobiology of disease (01.07.2006)
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Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance
Thomas, Mnlanie H, Paris, Cndric, Magnien, Mylene, Colin, Julie, Pelleieux, Sandra, Coste, Florence, Escanyn, Marie-Christine, Pillot, Thierry, Olivier, Jean-Luc
Published in Alzheimer's research & therapy (29.08.2017)
Published in Alzheimer's research & therapy (29.08.2017)
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Up-regulation of hepatic lipolysis stimulated lipoprotein receptor by leptin: a potential lever for controlling lipid clearance during the postprandial phase
Stenger, Christophe, Hanse, Marine, Pratte, Dagmar, Mbala, Marie-Ludvine, Akbar, Samina, Koziel, Violette, Escanyé, Marie-Christine, Kriem, Badreddine, Malaplate-Armand, Catherine, Olivier, Jean-Luc, Oster, Thierry, Pillot, Thierry, Yen, Frances T
Published in The FASEB journal (01.11.2010)
Published in The FASEB journal (01.11.2010)
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Journal Article
Towards a nutritional approach for prevention of Alzheimer's disease: Biochemical and cellular aspects
Florent-Béchard, Sabrina, Malaplate-Armand, Catherine, Koziel, Violette, Kriem, Badreddine, Olivier, Jean-Luc, Pillot, Thierry, Oster, Thierry
Published in Journal of the neurological sciences (15.11.2007)
Published in Journal of the neurological sciences (15.11.2007)
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Human apolipoprotein C-I expression in mice impairs learning and memory functions
Abildayeva, Karlygash, Berbée, Jimmy F.P., Blokland, Arjan, Jansen, Paula J., Hoek, Frans J., Meijer, Onno, Lütjohann, Dieter, Gautier, Thomas, Pillot, Thierry, De Vente, Jan, Havekes, Louis M., Ramaekers, Frans C.S., Kuipers, Folkert, Rensen, Patrick C.N., Mulder, Monique
Published in Journal of lipid research (01.04.2008)
Published in Journal of lipid research (01.04.2008)
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The Cellular Prion Protein PrPc Is Expressed in Human Enterocytes in Cell-Cell Junctional Domains
Morel, Etienne, Fouquet, Stephane, Chateau, Danielle, Yvernault, Lucile, Frobert, Yveline, Pinçon-Raymond, Martine, Chambaz, Jean, Pillot, Thierry, Rousset, Monique
Published in The Journal of biological chemistry (09.01.2004)
Published in The Journal of biological chemistry (09.01.2004)
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N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
Bouter, Yvonne, Dietrich, Katharina, Wittnam, Jessica L., Rezaei-Ghaleh, Nasrollah, Pillot, Thierry, Papot-Couturier, Sophie, Lefebvre, Thomas, Sprenger, Frederick, Wirths, Oliver, Zweckstetter, Markus, Bayer, Thomas A.
Published in Acta neuropathologica (01.08.2013)
Published in Acta neuropathologica (01.08.2013)
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Neuroprotective effects of DHA in Alzheimer's disease models
FLORENT-BECHARD, Sabrina, KOZIEL, Violette, OLIVIER, Jean-Luc, OSTER, Thierry, PILLOT, Thierry
Published in OCL. Oléagineux, corps gras, lipides (01.05.2007)
Published in OCL. Oléagineux, corps gras, lipides (01.05.2007)
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Conference Proceeding
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Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties
Dorard, Emilie, Chasseigneaux, Stéphanie, Gorisse-Hussonnois, Lucie, Broussard, Cédric, Pillot, Thierry, Allinquant, Bernadette
Published in Molecular neurobiology (01.07.2018)
Published in Molecular neurobiology (01.07.2018)
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Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy
Piechotta, Anke, Parthier, Christoph, Kleinschmidt, Martin, Gnoth, Kathrin, Pillot, Thierry, Lues, Inge, Demuth, Hans-Ulrich, Schilling, Stephan, Rahfeld, Jens-Ulrich, Stubbs, Milton T.
Published in The Journal of biological chemistry (28.07.2017)
Published in The Journal of biological chemistry (28.07.2017)
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Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease
Garcia, Pierre, Youssef, Ihsen, Utvik, Jo K, Florent-Béchard, Sabrina, Barthélémy, Vanassa, Malaplate-Armand, Catherine, Kriem, Badreddine, Stenger, Christophe, Koziel, Violette, Olivier, Jean-Luc, Escanye, Marie-Christine, Hanse, Marine, Allouche, Ahmad, Desbène, Cédric, Yen, Frances T, Bjerkvig, Rolf, Oster, Thierry, Niclou, Simone P, Pillot, Thierry
Published in The Journal of neuroscience (02.06.2010)
Published in The Journal of neuroscience (02.06.2010)
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Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X
Antonios, Gregory, Borgers, Henning, Richard, Bernhard C., Brauß, Andreas, Meißner, Julius, Weggen, Sascha, Pena, Vladimir, Pillot, Thierry, Davies, Sarah L., Bakrania, Preeti, Matthews, David, Brownlees, Janet, Bouter, Yvonne, Bayer, Thomas A.
Published in Scientific reports (02.12.2015)
Published in Scientific reports (02.12.2015)
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Stabilized Low-n Amyloid-β Oligomers Induce Robust Novel Object Recognition Deficits Associated with Inflammatory, Synaptic, and GABAergic Dysfunction in the Rat
Watremez, William, Jackson, Joshua, Almari, Bushra, McLean, Samantha L, Grayson, Ben, Neill, Joanna C, Fischer, Nicolas, Allouche, Ahmad, Koziel, Violette, Pillot, Thierry, Harte, Michael K
Published in Journal of Alzheimer's disease (01.01.2018)
Published in Journal of Alzheimer's disease (01.01.2018)
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Journal Article
P4‐271: Alpha‐Synuclein Oligomer Preparations Induce Neurodegeneration and Cognitive Decline: a Novel Model for Parkinson’s DISEASE
Pillot, Thierry, Goetghebeur, P., Rimet, D., Fischer, N., Terroire, Y., Colin, S., Allouche, A., Koziel, V., Kopke, A.K.E.
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis
Youssef, Ihsen, Florent-Béchard, Sabrina, Malaplate-Armand, Catherine, Koziel, Violette, Bihain, Bernard, Olivier, Jean-Luc, Leininger-Muller, Brigitte, Kriem, Badreddine, Oster, Thierry, Pillot, Thierry
Published in Neurobiology of aging (01.09.2008)
Published in Neurobiology of aging (01.09.2008)
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Critical role of cPLA2 in Aβ oligomer-induced neurodegeneration and memory deficit
Desbène, Cédric, Malaplate-Armand, Catherine, Youssef, Ihsen, Garcia, Pierre, Stenger, Christophe, Sauvée, Mathilde, Fischer, Nicolas, Rimet, Dorine, Koziel, Violette, Escanyé, Marie-Christine, Oster, Thierry, Kriem, Badreddine, Yen, Frances T, Pillot, Thierry, Olivier, Jean Luc
Published in Neurobiology of aging (01.06.2012)
Published in Neurobiology of aging (01.06.2012)
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COGNITIVE PROFILE OF S 68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS
Danober, Laurence, Dores, Guillaume Das, Louis, Caroline, Llopis, Karine, Dumas, Nathalie, Liard, Catherine, Girardon, Sylvie, Catherine, Le Quement, Bureau, Marie, Krazem, Ali, Béracochéa, Daniel, Pillot, Thierry, Le Diguarher, Thierry, Bertrand, Marc, Benoist, Alain, Fourquez, Jean-Marie, Chollet, Anne-Marie, Gloanec, Philippe, Jeggo, Ross
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
P3‐043: COGNITIVE PROFILE OF S 68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS
Danober, Laurence, Dores, Guillaume Das, Louis, Caroline, Llopis, Karine, Dumas, Nathalie, Liard, Catherine, Girardon, Sylvie, Catherine, Le Quement, Bureau, Marie, Krazem, Ali, Béracochéa, Daniel, Pillot, Thierry, Le Diguarher, Thierry, Bertrand, Marc, Benoist, Alain, Fourquez, Jean-Marie, Chollet, Anne-Marie, Gloanec, Philippe, Jeggo, Ross
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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