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2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, MIDDELTON, Donald, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 28.04.2021

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Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo [1,5-a] pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, the preparation of said compound and different solid forms thereof

Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo [1,5-a] pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, the preparation of said compound and different solid forms thereof

by Panesar, Maninder, Davis, Chris, Studley, John, Charrier, Jean-Damien, Storck, Pierre-Henri, Etxebarria I Jardi, Gorka, Knegtel, Ronald, Fraysse, Damien, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne
Year of Publication 16.05.2019

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PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

by PIERARD, Francoise, KAY, David, JIMENEZ, Juan-Miguel, ODONNELL, Michael, KNEGTEL, Roland, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, FRAYSSE, Damine, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 21.04.2021

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2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by SHAW, DAVID MATTHEW, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, PINDER, JOANNE, PANESAR, MANINDER, ALEM, NAZIHA, PIERARD, FRANCOISE, SANGHVI, TAPAN, PEGG, SIMON, FRAYSSE, DAMIEN, WALDO, MICHAEL, MEDEK, ALES, ZHANG, YUEGANG, DAVIS, CHRISTOPHER JOHN, ZWICKER, CARL
Year of Publication 30.04.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, Nadia, PIERARD, Francoise, PINDER, Joanne, STUDLEY, John, FRAYSSE, Damien, PANESAR, Maninder, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, CHARRIER, Jean-Damien, DAVIS, Chris, STORCK, Pierre-Henri
Year of Publication 29.04.2019

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Process for making compounds useful as inhibitors of ATR kinase

Process for making compounds useful as inhibitors of ATR kinase

by LITTLER, BENJAMIN JOSEPH, HUGHES, ROBERT MICHAEL, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, DURRANT, STEVEN JOHN, URBINA, ARMANDO, SIESEL, DAVID ANDREW, PIERARD, FRANCOISE YVONNE THEODORA MARIE, ANGELL, PAUL, SHI, YI
Year of Publication 31.03.2020

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2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by PIERARD, Francoise, ZWICKER, Carl, ZHANG, Yuegang, MEDEK, Ales, FRAYSSE, Damien, PEGG, Simon, CHARRIER, Jean-Damien, ALEM, Naziha, SANGHVI, Tapan, WALDO, Michael, PINDER, Joanne, STUDLEY, John, SHAW, David, PANESAR, Maninder, DAVIS, Christopher, ETXEBARRIA I JARDI, Gorka
Year of Publication 30.03.2020

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PYRAZOLO(1,5-A)PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

PYRAZOLO(1,5-A)PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

by DAVIS Chris, KNEGTEL Ronald, FRAYSSE Damine, DAVIS Rebecca, JIMENEZ Juan-Miguel, ETXEBARRIA I JARDI Gorka, PIERARD Francoise, AHMAD Nadia, ODONNELL Michael, STUDLEY John, BOYALL Dean, TWIN Heather, MIDDLETON Donald, PANESAR Maninder, KAY David, SHAW David, CHARRIER Jean-Damien, DURRANT Steven, PINDER Joanne, STORCK Pierre-Henri
Year of Publication 26.02.2021

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PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

by AHMAD, NADIA, DAVIS, REBECCA, DURRANT, STEVEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, KAY, DAVID, DAVIS, CHRIS, PINDER, JOANNE, SHAW, DAVID, JIMENEZ, JUAN-MIGUEL, PANESAR, MANINDER, PIERARD, FRANCOISE, FRAYSSE, DAMINE, MIDDLETON, DONALD, ODONNELL, MICHAEL, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, BOYALL, DEAN
Year of Publication 26.02.2021

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PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

by Odonnell, Michael, Davis, Chris, Twin, Heather, Charrier, Jean-Damien, Kay, David, Knegtel, Ronald, Fraysse, Damien, Jimenez, Juan-Miguel, Shaw, David, Panesar, Maninder, Studley, John, Storck, Pierre-Henri, Davis, Rebecca, Etxebarria I Jardi, Gorka, Middleton, Donald, Boyall, Dean, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne, Durrant, Steven
Year of Publication 19.02.2021

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2-AMINO-6-FLUORO-N-(5-FLUORO-PYRIDIN-3-YL)PYRAZOLO(1,5-A)PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-(5-FLUORO-PYRIDIN-3-YL)PYRAZOLO(1,5-A)PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by ETXEBARRIA I JARDI Gorka, PIERARD Francoise, SHAW David Matthew, STUDLEY John, ZWICKER Carl, ZHANG Yuegang, SANGHVI Tapan, DAVIS Christopher John, PEGG Simon, FRAYSSE Damien, WALDO Michael, PANESAR Maninder, MEDEK Ales, ALEM Naziha, CHARRIER Jean-Damien, PINDER Joanne
Year of Publication 28.02.2020

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2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by Sanghvi, Tapan, Zwicker, Carl, Alem, Naziha, Charrier, Jean-Damien, Fraysse, Damien, Zhang, Yuegang, Shaw, David Matthew, Pegg, Simon, Waldo, Michael, Panesar, Maninder, Studley, John, Davis, Christopher John, Etxebarria I Jardi, Gorka, Pierard, Francoise, Pinder, Joanne, Medek, Ales
Year of Publication 21.02.2020

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Patent

Processes for preparing ATR inhibitors

Processes for preparing ATR inhibitors

by Shi, Yi, Pierard, Francoise Yvonne Theodora Marie, Studley, John, Siesel, David Andrew, Charrier, Jean-Damien, Littler, Benjamin Joseph, Durrant, Steven John, Hughes, Robert Michael, Angell, Paul, Urbina, Armando
Year of Publication 19.02.2019

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2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by SHAW, DAVID, MATTHEW, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, PINDER, JOANNE, DAVIS, CHRISTOPHER, JOHN, PANESAR, MANINDER, ALEM, NAZIHA, PIERARD, FRANCOISE, SANGHVI, TAPAN, PEGG, SIMON, FRAYSSE, DAMIEN, WALDO, MICHAEL, MEDEK, ALES, ZHANG, YUEGANG, ZWICKER, CARL
Year of Publication 31.01.2020

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2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-a]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-a]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

by PIERARD, Francoise, ZWICKER, Carl, ZHANG, Yuegang, MEDEK, Ales, FRAYSSE, Damien, PEGG, Simon, CHARRIER, Jean-Damien, ALEM, Naziha, SANGHVI, Tapan, WALDO, Michael, PINDER, Joanne, STUDLEY, John, SHAW, David, PANESAR, Maninder, DAVIS, Christopher, ETXEBARRIA I JARDI, Gorka
Year of Publication 27.01.2020

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PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES

by PIERARD, Francoise, KAY, David, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, FRAYSSE, Damine, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 11.01.2021

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4-(9-(3,3-DIFLUOROCYCLOPENTYL)-5,7,7-TRIMETHYL-6-OXO-6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-B[1,4]DIAZEPIN-2-YLAMINO)-3-METHOXYBENZAMIDE DERIVATIVES AS INHIBITORS OF THE HUMAN PROTEIN KINASES PLK1 TO PLK4 FOR THE TREATMENT OF PROLIFERATIVE DISEASES

4-(9-(3,3-DIFLUOROCYCLOPENTYL)-5,7,7-TRIMETHYL-6-OXO-6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-B[1,4]DIAZEPIN-2-YLAMINO)-3-METHOXYBENZAMIDE DERIVATIVES AS INHIBITORS OF THE HUMAN PROTEIN KINASES PLK1 TO PLK4 FOR THE TREATMENT OF PROLIFERATIVE DISEASES

by CHARRIER, JEAN-DAMIEN, PIERARD, FRANCOISE
Year of Publication 02.06.2010

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COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

by Panesar, Maninder, Davis, Chris, Studley, John, Charrier, Jean-Damien, Storck, Pierre-Henri, Etxebarria I Jardi, Gorka, Knegtel, Ronald, Fraysse, Damien, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne
Year of Publication 10.01.2019

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2-AMINO-6-FLUOR-N-[5-FLUOR-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDFORBINDELSE ANVENDELIG SOM ATR-KINASE-INHIBITOR, DENS FREMSTILLING, FORSKELLIGE FASTE FORMER OG RADIOMARKEREDE DERIVATER DERAF

2-AMINO-6-FLUOR-N-[5-FLUOR-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDFORBINDELSE ANVENDELIG SOM ATR-KINASE-INHIBITOR, DENS FREMSTILLING, FORSKELLIGE FASTE FORMER OG RADIOMARKEREDE DERIVATER DERAF

by PIERARD, Francoise, ZWICKER, Carl, ZHANG, Yuegang, MEDEK, Ales, FRAYSSE, Damien, PEGG, Simon, CHARRIER, Jean-Damien, ALEM, Naziha, SANGHVI, Tapan, WALDO, Michael, DAVIS, Christopher, John, PINDER, Joanne, SHAW, David, Matthew, STUDLEY, John, PANESAR, Maninder, ETXEBARRIA I JARDI, Gorka
Year of Publication 16.12.2019

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PYRAZOLO[1,5-A]PYRIMIDINER, DER ER ANVENDELIGE SOM INHIBITORER AF ATR-KINASE TIL BEHANDLING AF CANCERSYGDOMME

PYRAZOLO[1,5-A]PYRIMIDINER, DER ER ANVENDELIGE SOM INHIBITORER AF ATR-KINASE TIL BEHANDLING AF CANCERSYGDOMME

by PIERARD, Francoise, KAY, David, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, FRAYSSE, Damine, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 07.12.2020

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