Pharmacology of montelukast sodium (Singulair), a potent and selective leukotriene D4 receptor antagonist
Jones, T R, Labelle, M, Belley, M, Champion, E, Charette, L, Evans, J, Ford-Hutchinson, A W, Gauthier, J Y, Lord, A, Masson, P
Published in Canadian journal of physiology and pharmacology (01.02.1995)
Published in Canadian journal of physiology and pharmacology (01.02.1995)
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Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist
Jones, T R, Zamboni, R, Belley, M, Champion, E, Charette, L, Ford-Hutchinson, A W, Frenette, R, Gauthier, J Y, Leger, S, Masson, P
Published in Canadian journal of physiology and pharmacology (01.01.1989)
Published in Canadian journal of physiology and pharmacology (01.01.1989)
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L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor
Gillard, J, Ford-Hutchinson, A W, Chan, C, Charleson, S, Denis, D, Foster, A, Fortin, R, Leger, S, McFarlane, C S, Morton, H
Published in Canadian journal of physiology and pharmacology (01.05.1989)
Published in Canadian journal of physiology and pharmacology (01.05.1989)
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Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma
Jones, T R, McAuliffe, M, McFarlane, C S, Piechuta, H, Macdonald, D, Rodger, I W
Published in Canadian journal of physiology and pharmacology (01.02.1998)
Published in Canadian journal of physiology and pharmacology (01.02.1998)
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Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor
Brideau, C, Chan, C, Charleson, S, Denis, D, Evans, J F, Ford-Hutchinson, A W, Fortin, R, Gillard, J W, Guay, J, Guévremont, D
Published in Canadian journal of physiology and pharmacology (01.06.1992)
Published in Canadian journal of physiology and pharmacology (01.06.1992)
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Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (.+-.)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid
Zamboni, R, Belley, M, Champion, E, Charette, L, DeHaven, R, Frenette, R, Gauthier, J. Y, Jones, T. R, Leger, S
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816
Hutchinson, J. H, Riendeau, D, Brideau, C, Chan, C, Delorme, D, Denis, D, Falgueyret, J. P, Fortin, R, Guay, J
Published in Journal of medicinal chemistry (01.09.1993)
Published in Journal of medicinal chemistry (01.09.1993)
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Thiopyrano[2,3,4-cd]indoles as 5-Lipoxygenase Inhibitors: Synthesis, Biological Profile, and Resolution of 2-[2-[1-(4-Chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5-dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic Acid
Hutchinson, J. H, Riendeau, D, Brideau, C, Chan, C, Falgueyret, J.-P, Guay, J, Jones, T. R, Lepine, C, Macdonald, D
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
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The discovery of L-699,392, a novel potent and orally active leukotriene D 4 receptor antagonist
Labelle, M., Belley, M., Champion, E., Gordon, R., Hoogsteen, K., Jones, T.R., Leblanc, Y., Lord, A., McAuliffe, M., McFarlane, C., Masson, P., Metters, K.M., Nicoll-Griffith, D., Ouimet, N., Piechuta, H., Rochette, C., Sawyer, N., Xiang, Y.B., Yergey, J., Ford-Hutchinson, A.W., Pickett, C.B., Zamboni, R.J., Young, R.N.
Published in Bioorganic & medicinal chemistry letters (10.02.1994)
Published in Bioorganic & medicinal chemistry letters (10.02.1994)
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The discovery of L-699,392, a novel potent and orally active leukotriene D4 receptor antagonist
LABELLE, M, BELLEY, M, MASSON, P, METTERS, K. M, NICOLL-GRIFFITH, D, OUIMET, N, PIECHUTA, H, ROCHETTE, C, SAWYER, N, XIANG, Y. B, YERGEY, J, FORD-HUTCHINSON, A. W, CHAMPION, E, PICKETT, C. B, ZAMBONI, R. J, YOUNG, R. N, GORDON, R, HOOGSTEEN, K, JONES, T. R, LEBLANC, Y, LORD, A, MACAULIFFE, M, MCFARLANE, C
Published in Bioorganic & medicinal chemistry letters (10.02.1994)
Published in Bioorganic & medicinal chemistry letters (10.02.1994)
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The discovery of a new structural class of potent orally active leukotriene D4 antagonists
Labelle, M., Prasit, P., Belley, M., Blouin, M., Champion, E., Charette, L., DeLuca, J.G., Dufresne, C., Frenette, R., Gauthier, J.Y., Grimm, E., Grossman, S.J., Guay, D., Herold, E.G., Jones, T.R., Lau, C.K., Leblanc, Y., Léger, S., Lord, A., McAuliffe, M., McFarlane, C., Masson, P., Metters, K.M., Ouimet, N., Patrick, D.H., Perrier, H., Pickett, C.B., Piechuta, H., Roy, P., Williams, H., Wang, Z., Xiang, Y.B., Zamboni, R.J., Ford-Hutchinson, A.W., Young, R.N.
Published in Bioorganic & medicinal chemistry letters (01.09.1992)
Published in Bioorganic & medicinal chemistry letters (01.09.1992)
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Respiratory responses to leukotrienes and biogenic amines in normal and hyperreactive rats
Brunet, G, Piechuta, H, Hamel, R, Holme, G, Ford-Hutchinson, AW
Published in The Journal of immunology (1950) (01.07.1983)
Published in The Journal of immunology (1950) (01.07.1983)
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Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571
Jones, T R, Zamboni, R, Belley, M, Champion, E, Charette, L, Ford-Hutchinson, A W, Gauthier, J Y, Leger, S, Lord, A, Masson, P
Published in Canadian journal of physiology and pharmacology (01.12.1991)
Published in Canadian journal of physiology and pharmacology (01.12.1991)
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L-649,923, sodium (beta S, gamma R)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)- gamma-hydroxy-beta-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist
Jones, T R, Young, R, Champion, E, Charette, L, Denis, D, Ford-Hutchinson, A W, Frenette, R, Gauthier, J Y, Guindon, Y, Kakushima, M
Published in Canadian journal of physiology and pharmacology (01.08.1986)
Published in Canadian journal of physiology and pharmacology (01.08.1986)
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L-656,224 (7-chloro-2-[(4-methoxyphenyl)methyl]-3- methyl-5-propyl-4-benzofuranol): a novel, selective, orally active 5-lipoxygenase inhibitor
Belanger, P, Maycock, A, Guindon, Y, Bach, T, Dollob, A L, Dufresne, C, Ford-Hutchinson, A W, Gale, P H, Hopple, S, Lau, C K
Published in Canadian journal of physiology and pharmacology (01.12.1987)
Published in Canadian journal of physiology and pharmacology (01.12.1987)
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A new class of leukotriene biosynthesis inhibitors: The development of ((4-(4-chlorophenyl)-1-(4-(2-quinolinylmethoxy)phenyl)butyl)thio)acetic acid, L-674,636
Prasit, P., Belley, M., Evans, J.F., Gauthier, J.Y., Léveillé, C., McFarlane, C.S., MacIntyre, E., Peterson, L., Piechuta, H., Thérien, M., Young, R.N., Zamboni, R.
Published in Bioorganic & medicinal chemistry letters (1991)
Published in Bioorganic & medicinal chemistry letters (1991)
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