Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma
Capone, Emily, Lamolinara, Alessia, Pastorino, Fabio, Gentile, Roberta, Ponziani, Sara, Di Vittorio, Giulia, D’Agostino, Daniela, Bibbò, Sandra, Rossi, Cosmo, Piccolo, Enza, Iacobelli, Valentina, Lattanzio, Rossano, Panella, Valeria, Sallese, Michele, De Laurenzi, Vincenzo, Giansanti, Francesco, Sala, Arturo, Iezzi, Manuela, Ponzoni, Mirco, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
Published in Cancers (01.10.2020)
Published in Cancers (01.10.2020)
Get full text
Journal Article
Strain- and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum
Okyar, Alper, Piccolo, Enza, Ahowesso, Constance, Filipski, Elisabeth, Hossard, Virginie, Guettier, Catherine, La Sorda, Rosanna, Tinari, Nicola, Iacobelli, Stefano, Lévi, Francis
Published in PloS one (03.06.2011)
Published in PloS one (03.06.2011)
Get full text
Journal Article
Inhibition of the phosphatidylinositol 3-kinase/akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects
MAFFUCCI, Tania, PICCOLO, Enza, POTTER, Barry V. L, INNOCENTI, Paolo, FALASCA, Marco, CUMASHI, Albana, IEZZI, Manuela, RILEY, Andrew M, SAIARDI, Adolfo, GODAGE, H. Yasmin, ROSSI, Cosmo, BROGGINI, Massimo, IACOBELLI, Stefano
Published in Cancer research (Chicago, Ill.) (15.09.2005)
Published in Cancer research (Chicago, Ill.) (15.09.2005)
Get full text
Journal Article
Inositol pentakisphosphate promotes apoptosis through the PI 3-K Akt pathway
PICCOLO, Enza, VIGNATI, Sara, FALASCA, Marco, MAFFUCCI, Tania, INNOMINATO, Pasquale F, RILEY, Andrew M, POTTER, Barry V. L, PANDOLFI, Pier Paolo, BROGGINI, Massimo, IACOBELLI, Stefano, INNOCENTI, Paolo
Published in Oncogene (04.03.2004)
Published in Oncogene (04.03.2004)
Get full text
Journal Article
The mechanism involved in the regulation of phospholipase Cγ1 activity in cell migration
PICCOLO, Enza, INNOMINATO, Pasquale F, MARIGGIO, Maria A, MALFUCCI, Tania, IACOBELLI, Stefano, FALASCA, Marco
Published in Oncogene (19.09.2002)
Published in Oncogene (19.09.2002)
Get full text
Journal Article
Synthetic Inhibitors of Galectin-1 and -3 Selectively Modulate Homotypic Cell Aggregation and Tumor Cell Apoptosis
IURISCI, Ida, CUMASHI, Albana, IACOBELLI, Stefano, NIFANTIEV, Nikolay E, SHERMAN, Andrei A, TSVETKOV, Yury E, TINARI, Nicola, PICCOLO, Enza, D'EGIDIO, Maurizia, ADAMO, Vincenzo, NATOLI, Clara, RABINOVICH, Gabriel A
Published in Anticancer research (01.01.2009)
Get full text
Published in Anticancer research (01.01.2009)
Journal Article
90K (Mac-2 BP) and galectins in tumor progression and metastasis
Grassadonia, Antonino, Tinari, Nicola, Iurisci, Ida, Piccolo, Enza, Cumashi, Alba, Innominato, Pasquale, D'Egidio, Maurizia, Natoli, Clara, Piantelli, Mauro, Iacobelli, Stefano
Published in Glycoconjugate journal (2002)
Published in Glycoconjugate journal (2002)
Get full text
Journal Article
Reorganization of actin cytoskeleton by the phosphoinositide metabolite glycerophosphoinositol 4-phosphate
Mancini, Raffaella, Piccolo, Enza, Mariggio', Stefania, Filippi, Beatrice Maria, Iurisci, Cristiano, Pertile, Paolo, Berrie, Christopher P, Corda, Daniela
Published in Molecular biology of the cell (01.02.2003)
Published in Molecular biology of the cell (01.02.2003)
Get full text
Journal Article
Secreted Gal-3BP is a novel promising target for non-internalizing Antibody–Drug Conjugates
Giansanti, Francesco, Capone, Emily, Ponziani, Sara, Piccolo, Enza, Gentile, Roberta, Lamolinara, Alessia, Di Campli, Antonella, Sallese, Michele, Iacobelli, Valentina, Cimini, Annamaria, De Laurenzi, Vincenzo, Lattanzio, Rossano, Piantelli, Mauro, Ippoliti, Rodolfo, Sala, Gianluca, Iacobelli, Stefano
Published in Journal of controlled release (28.01.2019)
Published in Journal of controlled release (28.01.2019)
Get full text
Journal Article
Abstract 748: Non-internalizing site-specific antibody-drug conjugates based on maytansinoids display curative properties
Sala, Gianluca, Capone, Emily, Piccolo, Enza, Ponziani, Sara, Gentile, Roberta, Ippoliti, Rodolfo, Giansanti, Francesco, Iacobelli, Stefano
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling
Okyar, Alper, Kumar, Swati A, Filipski, Elisabeth, Piccolo, Enza, Ozturk, Narin, Xandri-Monje, Helena, Pala, Zeliha, Abraham, Kristin, Gomes, Ana Rita Gato de Jesus, Orman, Mehmet N, Li, Xiao-Mei, Dallmann, Robert, Lévi, Francis, Ballesta, Annabelle
Published in Scientific reports (19.07.2019)
Published in Scientific reports (19.07.2019)
Get full text
Journal Article
Abstract 40: Development of a novel antibody-drug conjugate targeting endosialin/TEM-1: potent antitumor activity in sarcoma
Sala, Gianluca, Iacobelli, Stefano, Capone, Emily, PIccolo, Enza, Sauniere, Jean-Fred, Douet, Vanessa Vannucci
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis
Piccolo, Enza, Tinari, Nicola, Semeraro, Daniela, Traini, Sara, Fichera, Imma, Cumashi, Albana, La Sorda, Rossana, Spinella, Francesca, Bagnato, Anna, Lattanzio, Rossano, D’Egidio, Maurizia, Di Risio, Annalisa, Stampolidis, Pavlos, Piantelli, Mauro, Natoli, Clara, Ullrich, Axel, Iacobelli, Stefano
Published in Journal of molecular medicine (Berlin, Germany) (2013)
Published in Journal of molecular medicine (Berlin, Germany) (2013)
Get full text
Journal Article
Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma
Capone, Emily, Piccolo, Enza, Fichera, Imma, Ciufici, Paolo, Barcaroli, Daniela, Sala, Arturo, De Laurenzi, Vincenzo, Iacobelli, Valentina, Iacobelli, Stefano, Sala, Gianluca
Published in Oncotarget (01.09.2017)
Published in Oncotarget (01.09.2017)
Get full text
Journal Article
Prognostic relevance of LGALS3BP in human colorectal carcinoma
Piccolo, Enza, Tinari, Nicola, D'Addario, Domenica, Rossi, Cosmo, Iacobelli, Valentina, La Sorda, Rossana, Lattanzio, Rossano, D'Egidio, Maurizia, Di Risio, Annalisa, Piantelli, Mauro, Natali, Pier Giorgio, Iacobelli, Stefano
Published in Journal of translational medicine (30.07.2015)
Published in Journal of translational medicine (30.07.2015)
Get full text
Journal Article
Inhibition of tumor growth and angiogenesis by SP-2, an anti-lectin, galactoside-binding soluble 3 binding protein (LGALS3BP) antibody
Traini, Sara, Piccolo, Enza, Tinari, Nicola, Rossi, Cosmo, La Sorda, Rossana, Spinella, Francesca, Bagnato, Anna, Lattanzio, Rossano, D'Egidio, Maurizia, Di Risio, Annalisa, Tomao, Federica, Grassadonia, Antonino, Piantelli, Mauro, Natoli, Clara, Iacobelli, Stefano
Published in Molecular cancer therapeutics (01.04.2014)
Published in Molecular cancer therapeutics (01.04.2014)
Get full text
Journal Article
Tumor-derived microvesicles: The metastasomes
Ghasemi, Reza, Grassadonia, Antonino, Tinari, Nicola, Piccolo, Enza, Natoli, Clara, Tomao, Federica, Iacobelli, Stefano
Published in Medical hypotheses (01.01.2013)
Published in Medical hypotheses (01.01.2013)
Get full text
Journal Article
Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation
Falasca, Marco, Maffucci, Tania, Brancaccio, Anna, Piccolo, Enza, Stein, Robert C
Published in The EMBO journal (15.08.2003)
Published in The EMBO journal (15.08.2003)
Get full text
Journal Article
Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis
Rabinovich, Gabriel A., Cumashi, Albana, Bianco, Germán A., Ciavardelli, Domenico, Iurisci, Ida, D’Egidio, Maurizia, Piccolo, Enza, Tinari, Nicola, Nifantiev, Nikolay, Iacobelli, Stefano
Published in Glycobiology (Oxford) (01.03.2006)
Published in Glycobiology (Oxford) (01.03.2006)
Get full text
Journal Article
Abstract 2684: Inhibition of tumor growth and angiogenesis by SP-2, an anti-LGALS3BP antibody
Piccolo, Enza, Trani, Sara, Tinari, Nicola, Rossi, Cosmo, Sorda, Rossana L., Lattanzio, Rossano, D'Egidio, Maurizia, Risio, Annalisa D., Grassadonia, Antonino, Spinella, Francesca, Bagnato, Anna, Piantelli, Mauro, Natoli, Clara, Iacobelli, Stefano
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article