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A Phase I Trial of Sirolimus with “7&3” Induction Chemotherapy in Patients with Newly Diagnosed Acute Myeloid Leukemia
Palmisiano, Neil, Jeschke, Grace, Wilde, Lindsay, Alpdogan, Onder, Carabasi, Matthew, Filicko-O’Hara, Joanne, Grosso, Dolores, Klumpp, Thomas, Martinez, Ubaldo, Wagner, John, Carroll, Martin P., Perl, Alexander, Kasner, Margaret
Published in Cancers (25.10.2023)
Published in Cancers (25.10.2023)
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Journal Article
CTNI-59. RARE AND NOVEL KIAA1549-BRAF FUSION BREAKPOINTS PREDICT POOR CLINICAL OUTCOME FOR PATIENTS WITH RECURRENT OR PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMA: PHASE II PNOC001 TRIAL RESULTS
Waszak, Sebastian, Aboian, Mariam, Minturn, Jane, Leary, Sarah, Abdelbaki, Mohamed S, Goldman, Stewart, Elster, Jennifer, Kraya, Adam, Lueder, Matthew, Ramakrishnan, Divya, von Reppert, Marc, Liu, Kevin, Resnick, Adam, Solomon, David, Molinaro, Annette, Phillips, Joanna, Prados, Michael, Haas-Kogan, Daphne, Mueller, Sabine
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
Surgical window-of-opportunity study of megestrol acetate compared with megestrol acetate and metformin for endometrial intraepithelial neoplasia
Xu, Yanfei, Saiz, Allison, Rimel, Bj, Corr, Bradley, Secord, Angeles Alvarez, Clark, Leslie Horn, Kocherginsky, Masha, Schering, Tia, Benante, Kelly A., Kalinichenko, Kiril, Sauter, Edward, Samimi, Goli, Dimond, Eileen, Khan, Seema Ahsan, Barber, Emma Longley
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Primary Mediastinal Large B-Cell Lymphoma: A Phase 2 Study
Bennani, N. Nora, Nowakowski, Grzegorz, Rimsza, Lisa M., Adjei, Alex A, Doyle, Laurence, Ansell, Stephen M
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Potential roads for reaching the summit: an overview on target therapies for high-grade gliomas
Giotta Lucifero, Alice, Luzzi, Sabino, Brambilla, Ilaria, Schena, Lucia, Mosconi, Mario, Foiadelli, Thomas, Savasta, Salvatore
Published in Acta bio-medica de l'Ateneo Parmense (30.06.2020)
Published in Acta bio-medica de l'Ateneo Parmense (30.06.2020)
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Journal Article
Breast Cancer-Associated Fibroblasts Could Induce the PI3K/Akt/ mTOR Signaling Pathway Through Downstream Long Non-Coding RNA HOTAIR
Sadeghalvad, Mona, Mohammadi-Motlagh, Hamid-Reza, Mansouri, Kamran, Mostafaie, Ali, Noorbakhsh, Farshid, Alipour, Sadaf, Ghalkhani, Foroozan, Omranipour, Ramesh, Miraghaee, Seid-Shahram, Kiani, Sarah, Rezaei, Nima
Published in Immunology and Genetics Journal (28.02.2025)
Published in Immunology and Genetics Journal (28.02.2025)
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Journal Article
PTEN regulates starburst amacrine cell dendrite morphology during development
Bracha, Teva W, Luong, Nina, Leffler, Joseph, Sivyer, Benjamin, Wright, Kevin M
Published in bioRxiv (08.05.2025)
Published in bioRxiv (08.05.2025)
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Journal Article
Paper
A phase II study of sequential decitabine and rapamycin in acute myelogenous leukemia
Liesveld, Jane L., Baran, Andrea, Azadniv, Mitra, Misch, Haley, Nedrow, Katherine, Becker, Michael, Loh, Kah Poh, O’Dwyer, Kristen M., Mendler, Jason H.
Published in Leukemia research (01.01.2022)
Published in Leukemia research (01.01.2022)
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Journal Article
LGG-53. PNOC001 (NCT01734512): A PHASE II STUDY OF EVEROLIMUS FOR RECURRENT OR PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMAS (pLGG)
Mueller, Sabine, Aboian, Mariam, Nazemi, Kellie, Gauvain, Karen, Yoon, Janet, Minturn, Jane, Leary, Sarah, AbdelBaki, Mohamed S, Goldman, Stewart, Elster, Jennifer, Resnick, Adam, Molinaro, Annette M, Phillips, Joanna, Prados, Michael, Haas-Kogan, Daphne
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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Journal Article
Understanding how AKT phosphorylation of hnRNPA1 modulates T cell fate and function
White, Theresa L, Gable, Matthew, Jin, Ye, Morel, Penelope
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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Journal Article
Abstract P3-11-17: A Randomized Phase II Trial of Neo-adjuvant Chemotherapy with Metformin or Placebo for HER-2 Positive Operable Breast Cancer (The HERMET Trial)
Okoniewski, Maire, Bivona, Cory, Bohnenkamp, Colleen, Diaz, Francisco, Dai, Junqiang, Nye, Lauren, O'Dea, Anne, Larson, Kelsey, Satelli, Deepti, Wagner, Jamie, Balanoff, Christa, Kilgore, Lyndsey, Lafaver, Stephanie, Heldstab, Jamie, Sharma, Priyanka, Khan, Qamar
Published in Clinical cancer research (13.06.2025)
Published in Clinical cancer research (13.06.2025)
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Journal Article
PI3K/AKT/MTOR SIGNALING PATHWAY – A KEY PLAYER IN THE MOLECULAR LANDSCAPE OF MALIGNANT TRANSFORMATION OF ORAL LESIONS
Moisa, Mihai Radu, Coculescu, Elena Claudia, Imre, Marina, Ripszky, Alexandra, Coculescu, Bogdan-Ioan, Pituru, Silviu Mirel
Published in Romanian Journal of Oral Rehabilitation (15.03.2024)
Published in Romanian Journal of Oral Rehabilitation (15.03.2024)
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Journal Article
Enhanced PI3K/AKT/mTOR responses are associated with resistance to activation-induced cell death and expansion of memory CD4+ T cells in T1D subjects and healthy carriers of the PTPN22 risk variant
Habib, Tania J, Turner, Michael S, Anderson, Warren, Funk, Andrew, Rieck, Mary, Puri, Kamal D, Greenbaum, Carla, Long, S Alice, Buckner, Jane H
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Journal Article
Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation
EL-MASRY, OMAR S, AL-SAKKAf, KALTOOM, BROWN, BARRY L, DOBSON, PAULINE R.M
Published in Oncology reports (01.10.2015)
Published in Oncology reports (01.10.2015)
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Journal Article
Abstract P5-21-06: Alpelisib plus letrozole in estrogen receptor-Positive (ER+), human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer (aBC): Safety and preliminary efficacy analysis from a phase 1b trial
Juric, D, Gonçalves, A, Hamilton, E, Boni, V, Mayer, IA, Turri, S, Wang, Y, Vogl, FD, Sellami, D, Campone, M
Published in Cancer research (Chicago, Ill.) (15.02.2018)
Published in Cancer research (Chicago, Ill.) (15.02.2018)
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Journal Article
Abstract A68: Activity of the TORC 1/2 kinase inhibitor, CC-223, in hormone receptor positive (HR+) breast cancer cell lines and patients (pts) with genetically characterized HR+ breast cancer in a Phase I clinical trial
Mita, Monica M., Arkenau, Hendrik-Tobias, Bendell, Johanna C., Munster, Pamela N., Mahipal, Amit, Delord, Jean-Pierre, Paz-Ares, Luis G., Soria, Jean-Charles, Xu, Shuichan, Tran, Tam, Shi, Tao, Wu, Xiaoling, Chopra, Rajesh, Hege, Kristen, Varga, Andrea
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
A comprehensive review on the molecular basis and therapeutic targets in prostate cancer
Militaru, Florentina Claudia, Militaru, Valentin, Crisan, Nicolae, Bocsan, Ioana Corina, Udrea, Anghel Adrian, Catana, Andreea, Kutasi, Eniko, Militaru, Mariela Sanda
Published in Biomolecules & biomedicine (04.04.2023)
Published in Biomolecules & biomedicine (04.04.2023)
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Journal Article
Abstract 3140: Differential clonal selection in tumor tissue and cell-free DNA from a neratinib-treated refractory breast cancer patient harboring an activating ERBB2 (HER2) mutation
Joenson, Lars, Yde, Christina W., Østrup, Olga, Mau-Sørensen, Morten, Nielsen, Finn C., Lassen, Ulrik
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
A pilot study of sirolimus (S) in subjects with Cowden syndrome (CS) with germ-line mutations in PTEN
Komiya, Takefumi, Blumenthal, Gideon Michael, Ballas, Marc S., Dechowdhury, Roopa, Manu, Michell, Fioravanti, Suzanne, Hornyak, Thomas J, Wank, Stephen, Weinstein, Douglas, Morris, Jennifer, Hewitt, Stephen M., Memmott, Regan, Dennis, Phillip A., Morrow, Betsy
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
PI3K/AKT/mTOR Inhibitor Drug Candidates for the Treatment of Hormone Resistant Breast Cancer: A Systematic Review
Oliveira, Lucas Bernardim de, Chao, Bárbara Mendes Paz, Bini, Ana Carolina Dorigoni, Cordeiro, Maria Elvira Ribeiro, Carraro, Emerson
Published in Journal of Advances in Medicine and Medical Research (06.04.2024)
Published in Journal of Advances in Medicine and Medical Research (06.04.2024)
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Journal Article