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Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects
Habtemariam, Bahru A, Karsten, Verena, Attarwala, Husain, Goel, Varun, Melch, Megan, Clausen, Valerie A, Garg, Pushkal, Vaishnaw, Akshay K, Sweetser, Marianne T, Robbie, Gabriel J, Vest, John
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Published in Clinical pharmacology and therapeutics (01.02.2021)
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Pharmacokinetics of Oral Nirmatrelvir/Ritonavir, a Protease Inhibitor for Treatment of COVID‐19, in Subjects With Renal Impairment
Toussi, Sima S., Neutel, Joel Michael, Navarro, Jesus, Preston, Richard Alfred, Shi, Haihong, Kavetska, Olga, LaBadie, Robert R., Binks, Michael, Chan, Phylinda L.S., Demers, Neil, Corrigan, Brian, Damle, Bharat
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Published in Clinical pharmacology and therapeutics (01.10.2022)
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Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK‐438 (vonoprazan), a novel potassium‐competitive acid blocker, in healthy male subjects
Jenkins, H., Sakurai, Y., Nishimura, A., Okamoto, H., Hibberd, M., Jenkins, R., Yoneyama, T., Ashida, K., Ogama, Y., Warrington, S.
Published in Alimentary pharmacology & therapeutics (01.04.2015)
Published in Alimentary pharmacology & therapeutics (01.04.2015)
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Population Pharmacokinetics of Upadacitinib Using the Immediate-Release and Extended-Release Formulations in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Phase I–III Clinical Trials
Klünder, Ben, Mittapalli, Rajendar K., Mohamed, Mohamed-Eslam F., Friedel, Anna, Noertersheuser, Peter, Othman, Ahmed A.
Published in Clinical pharmacokinetics (01.08.2019)
Published in Clinical pharmacokinetics (01.08.2019)
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Pharmacokinetics of YK‐1169 in healthy subjects and pharmacokinetic/pharmacodynamic analysis by Monte Carlo simulation
Li, You, Yan, Bingqian, Guo, Siwei, Tian, Miaomei, Li, Yuan, Tong, Huan, Yu, Yunsong, Shao, Jing, Xin, Yuxia, Chen, Hui, Xu, Bing, Li, Xin
Published in British journal of clinical pharmacology (01.10.2023)
Published in British journal of clinical pharmacology (01.10.2023)
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Safety, tolerability, pharmacokinetics and pharmacokinetic‐pharmacodynamic modelling of the novel H 4 receptor inhibitor SENS‐111 using a modified caloric test in healthy subjects
Venail, Frédéric, Attali, Pierre, Wersinger, Eric, Gomeni, Roberto, Poli, Sonia, Schmerber, Sebastien
Published in British journal of clinical pharmacology (01.12.2018)
Published in British journal of clinical pharmacology (01.12.2018)
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Population pharmacokinetics of levornidazole in healthy subjects and patients and sequential dosing regimen proposal using pharmacokinetic/pharmacodynamic analysis
Cao, Yuran, Li, Yi, Guo, Beining, Zhang, Jing, Wu, Xiaojie, Yu, Jicheng, Cao, Guoying, Fan, Yaxin, Wu, Hailan
Published in International journal of antimicrobial agents (01.04.2023)
Published in International journal of antimicrobial agents (01.04.2023)
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Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects
Humeniuk, Rita, Mathias, Anita, Cao, Huyen, Osinusi, Anu, Shen, Gong, Chng, Estelle, Ling, John, Vu, Amanda, German, Polina
Published in Clinical and translational science (01.09.2020)
Published in Clinical and translational science (01.09.2020)
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Pharmacokinetics, pharmacodynamics, and safety of apixaban in subjects with end-stage renal disease on hemodialysis
Wang, Xiaoli, Tirucherai, Giridhar, Marbury, Thomas C, Wang, Jessie, Chang, Ming, Zhang, Donglu, Song, Yan, Pursley, Janice, Boyd, Rebecca A, Frost, Charles
Published in Journal of clinical pharmacology (01.05.2016)
Published in Journal of clinical pharmacology (01.05.2016)
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Excretion balance and pharmacokinetics following a single oral dose of [14C]-fedratinib in healthy subjects
Ogasawara, Ken, Xu, Christine, Kanamaluru, Vanaja, Siebers, Nicholas, Surapaneni, Sekhar, Ridoux, Laurence, Palmisano, Maria, Krishna, Gopal
Published in Cancer chemotherapy and pharmacology (01.08.2020)
Published in Cancer chemotherapy and pharmacology (01.08.2020)
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Population pharmacokinetics of adalimumab biosimilar adalimumab‐adbm and reference product in healthy subjects and patients with rheumatoid arthritis to assess pharmacokinetic similarity
Kang, Jia, Eudy‐Byrne, Rena J., Mondick, John, Knebel, William, Jayadeva, Girish, Liesenfeld, Karl‐Heinz
Published in British journal of clinical pharmacology (01.11.2020)
Published in British journal of clinical pharmacology (01.11.2020)
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Comparison of the pharmacokinetics, safety, and immunogenicity of MSB11022, a biosimilar of adalimumab, with Humira® in healthy subjects
Hyland, Elizabeth, Mant, Tim, Vlachos, Pantelis, Attkins, Neil, Ullmann, Martin, Roy, Sanjeev, Wagner, Volker
Published in British journal of clinical pharmacology (01.10.2016)
Published in British journal of clinical pharmacology (01.10.2016)
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Improved characterization of the pharmacokinetics of acalabrutinib and its pharmacologically active metabolite, ACP‐5862, in patients with B‐cell malignancies and in healthy subjects using a population pharmacokinetic approach
Edlund, Helena, Bellanti, Francesco, Liu, Huan, Vishwanathan, Karthick, Tomkinson, Helen, Ware, Joseph, Sharma, Shringi, Buil‐Bruna, Núria
Published in British journal of clinical pharmacology (01.02.2022)
Published in British journal of clinical pharmacology (01.02.2022)
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Pharmacokinetics and pharmacodynamics of γ‐hydroxybutyrate in healthy subjects
Liechti, Matthias E., Quednow, Boris B., Liakoni, Evangelia, Dornbierer, Dario, Rotz, Robin, Gachet, Maria Salomé, Gertsch, Jürg, Seifritz, Erich, Bosch, Oliver G.
Published in British journal of clinical pharmacology (01.05.2016)
Published in British journal of clinical pharmacology (01.05.2016)
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Pharmacokinetics, Disposition, and Biotransformation of [14C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose
Trivedi, Ashit, Wahlstrom, Jan, Mackowski, Mia, Dutta, Sandeep, Lee, Edward
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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A Phase I Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of A140 Injection and Cetuximab (Erbitux®) in Healthy Chinese Male Subjects
Xu, Jia, Ge, Junyou, Li, Yaling, Liu, Shulin, Li, Sicong, Si, Jing, Liu, Juncheng, Zhu, Xiaoxue, Ding, Yanhua
Published in Advances in therapy (01.06.2025)
Published in Advances in therapy (01.06.2025)
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Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects
Kubitza, Dagmar, Becka, Michael, Wensing, Georg, Voith, Barbara, Zuehlsdorf, Michael
Published in European journal of clinical pharmacology (01.12.2005)
Published in European journal of clinical pharmacology (01.12.2005)
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Mass balance, pharmacokinetics and pharmacodynamics of intravenous HSK3486, a novel anaesthetic, administered to healthy subjects
Bian, Yicong, Zhang, Hua, Ma, Sheng, Jiao, Yongyi, Yan, Pangke, Liu, Xiao, Ma, Shiping, Xiong, Yating, Gu, Zheming, Yu, Zhenwen, Huang, Chenrong, Miao, Liyan
Published in British journal of clinical pharmacology (01.01.2021)
Published in British journal of clinical pharmacology (01.01.2021)
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