Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system
Pfefferle, Susanne, Reucher, Svenja, Nörz, Dominic, Lütgehetmann, Marc
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (05.03.2020)
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (05.03.2020)
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Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
GLOWACKA, Ilona, BERTRAM, Stephanie, NIEMEYER, Daniela, SCHNEIDER, Heike, DROSTEN, Christian, PÖHLMANN, Stefan, MÜLLER, Marcel A, ALLEN, Paul, SOILLEUX, Elizabeth, PFEFFERLE, Susanne, STEFFEN, Imke, TSEGAYE, Theodros Solomon, YUXIAN HE, GNIRSS, Kerstin
Published in Journal of Virology (01.05.2011)
Published in Journal of Virology (01.05.2011)
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Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63
Glowacka, Ilona, Bertram, Stephanie, Herzog, Petra, Pfefferle, Susanne, Steffen, Imke, Muench, Marcus O, Simmons, Graham, Hofmann, Heike, Kuri, Thomas, Weber, Friedemann, Eichler, Jutta, Drosten, Christian, Pöhlmann, Stefan
Published in Journal of Virology (15.01.2010)
Published in Journal of Virology (15.01.2010)
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The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
Krasemann, Susanne, Haferkamp, Undine, Pfefferle, Susanne, Woo, Marcel S., Heinrich, Fabian, Schweizer, Michaela, Appelt-Menzel, Antje, Cubukova, Alevtina, Barenberg, Janica, Leu, Jennifer, Hartmann, Kristin, Thies, Edda, Littau, Jessica Lisa, Sepulveda-Falla, Diego, Zhang, Liang, Ton, Kathy, Liang, Yan, Matschke, Jakob, Ricklefs, Franz, Sauvigny, Thomas, Sperhake, Jan, Fitzek, Antonia, Gerhartl, Anna, Brachner, Andreas, Geiger, Nina, König, Eva-Maria, Bodem, Jochen, Franzenburg, Sören, Franke, Andre, Moese, Stefan, Müller, Franz-Josef, Geisslinger, Gerd, Claussen, Carsten, Kannt, Aimo, Zaliani, Andrea, Gribbon, Philip, Ondruschka, Benjamin, Neuhaus, Winfried, Friese, Manuel A., Glatzel, Markus, Pless, Ole
Published in Stem cell reports (08.02.2022)
Published in Stem cell reports (08.02.2022)
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Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection
Nörz, Dominik, Tang, Hui Ting, Emmerich, Petra, Giersch, Katja, Fischer, Nicole, Schmiedel, Stephan, Addo, Marylyn M, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Published in Emerging infectious diseases (01.09.2022)
Published in Emerging infectious diseases (01.09.2022)
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Implementation of the FilmArray ME panel in laboratory routine using a simple sample selection strategy for diagnosis of meningitis and encephalitis
Pfefferle, Susanne, Christner, Martin, Aepfelbacher, Martin, Lütgehetmann, Marc, Rohde, Holger
Published in BMC infectious diseases (22.02.2020)
Published in BMC infectious diseases (22.02.2020)
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Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes
Bouvet, Mickaël, Lugari, Adrien, Posthuma, Clara C., Zevenhoven, Jessika C., Bernard, Stéphanie, Betzi, Stéphane, Imbert, Isabelle, Canard, Bruno, Guillemot, Jean-Claude, Lécine, Patrick, Pfefferle, Susanne, Drosten, Christian, Snijder, Eric J., Decroly, Etienne, Morelli, Xavier
Published in The Journal of biological chemistry (12.09.2014)
Published in The Journal of biological chemistry (12.09.2014)
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Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
Heinrich, Fabian, Meißner, Kira, Langenwalder, Felicia, Püschel, Klaus, Nörz, Dominik, Hoffmann, Armin, Lütgehetmann, Marc, Aepfelbacher, Martin, Bibiza-Freiwald, Eric, Pfefferle, Susanne, Heinemann, Axel
Published in Emerging infectious diseases (01.01.2021)
Published in Emerging infectious diseases (01.01.2021)
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The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors
Pfefferle, Susanne, Schöpf, Julia, Kögl, Manfred, Friedel, Caroline C, Müller, Marcel A, Carbajo-Lozoya, Javier, Stellberger, Thorsten, von Dall'Armi, Ekatarina, Herzog, Petra, Kallies, Stefan, Niemeyer, Daniela, Ditt, Vanessa, Kuri, Thomas, Züst, Roland, Pumpor, Ksenia, Hilgenfeld, Rolf, Schwarz, Frank, Zimmer, Ralf, Steffen, Imke, Weber, Friedemann, Thiel, Volker, Herrler, Georg, Thiel, Heinz-Jürgen, Schwegmann-Wessels, Christel, Pöhlmann, Stefan, Haas, Jürgen, Drosten, Christian, von Brunn, Albrecht
Published in PLoS pathogens (01.10.2011)
Published in PLoS pathogens (01.10.2011)
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Genomic Characterization of Severe Acute Respiratory Syndrome-Related Coronavirus in European Bats and Classification of Coronaviruses Based on Partial RNA-Dependent RNA Polymerase Gene Sequences
Drexler, Jan Felix, Gloza-Rausch, Florian, Glende, Jörg, Corman, Victor Max, Muth, Doreen, Goettsche, Matthias, Seebens, Antje, Niedrig, Matthias, Pfefferle, Susanne, Yordanov, Stoian, Zhelyazkov, Lyubomir, Hermanns, Uwe, Vallo, Peter, Lukashev, Alexander, Müller, Marcel Alexander, Deng, Hongkui, Herrler, Georg, Drosten, Christian
Published in Journal of Virology (01.11.2010)
Published in Journal of Virology (01.11.2010)
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Journal Article
Molecular consequences of SARS-CoV-2 liver tropism
Wanner, Nicola, Andrieux, Geoffroy, Badia-i-Mompel, Pau, Edler, Carolin, Pfefferle, Susanne, Lindenmeyer, Maja T., Schmidt-Lauber, Christian, Czogalla, Jan, Wong, Milagros N., Okabayashi, Yusuke, Braun, Fabian, Lütgehetmann, Marc, Meister, Elisabeth, Lu, Shun, Noriega, Maria L. M., Günther, Thomas, Grundhoff, Adam, Fischer, Nicole, Bräuninger, Hanna, Lindner, Diana, Westermann, Dirk, Haas, Fabian, Roedl, Kevin, Kluge, Stefan, Addo, Marylyn M., Huber, Samuel, Lohse, Ansgar W., Reiser, Jochen, Ondruschka, Benjamin, Sperhake, Jan P., Saez-Rodriguez, Julio, Boerries, Melanie, Hayek, Salim S., Aepfelbacher, Martin, Scaturro, Pietro, Puelles, Victor G., Huber, Tobias B.
Published in Nature metabolism (01.03.2022)
Published in Nature metabolism (01.03.2022)
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A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells
Soh, Timothy K, Pfefferle, Susanne, Wurr, Stephanie, von Possel, Ronald, Oestereich, Lisa, Rieger, Toni, Uetrecht, Charlotte, Rosenthal, Maria, Bosse, Jens B
Published in PloS one (10.05.2023)
Published in PloS one (10.05.2023)
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A Single Asparagine-Linked Glycosylation Site of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Facilitates Inhibition by Mannose-Binding Lectin through Multiple Mechanisms
Zhou, Yanchen, Lu, Kai, Pfefferle, Susanne, Bertram, Stephanie, Glowacka, Ilona, Drosten, Christian, Pöhlmann, Stefan, Simmons, Graham
Published in Journal of Virology (01.09.2010)
Published in Journal of Virology (01.09.2010)
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Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths
Heinrich, Fabian, Schröder, Ann Sophie, Gerberding, Anna-Lina, Gerling, Moritz, Langenwalder, Felicia, Lange, Philine, Heinemann, Axel, Bibiza-Freiwald, Eric, Nörz, Dominik Sebastian, Aepfelbacher, Martin, Pfefferle, Susanne, Ondruschka, Benjamin, Lütgehetmann, Marc
Published in Emerging infectious diseases (01.01.2022)
Published in Emerging infectious diseases (01.01.2022)
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Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana
Pfefferle, Susanne, Oppong, Samuel, Drexler, Jan Felix, Gloza-Rausch, Florian, Ipsen, Anne, Seebens, Antje, Müller, Marcel A, Annan, Augustina, Vallo, Peter, Adu-Sarkodie, Yaw, Kruppa, Thomas F, Drosten, Christian
Published in Emerging infectious diseases (01.09.2009)
Published in Emerging infectious diseases (01.09.2009)
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Young COVID-19 Patients Show a Higher Degree of Microglial Activation When Compared to Controls
Matschke, Jakob, Lahann, Henri, Krasemann, Susanne, Altmeppen, Hermann, Pfefferle, Susanne, Galliciotti, Giovanna, Fitzek, Antonia, Sperhake, Jan-Peter, Ondruschka, Benjamin, Busch, Miriam, Rotermund, Natalie, Schulz, Kristina, Lohr, Christian, Dottermusch, Matthias, Glatzel, Markus
Published in Frontiers in neurology (16.06.2022)
Published in Frontiers in neurology (16.06.2022)
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Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants
Nörz, Dominik, Grunwald, Moritz, Tang, Hui Ting, Weinschenk, Celine, Günther, Thomas, Robitaille, Alexis, Giersch, Katja, Fischer, Nicole, Grundhoff, Adam, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Published in Viruses (15.03.2022)
Published in Viruses (15.03.2022)
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Journal Article
SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm, Thomas Theo, Pfefferle, Susanne, von Possel, Ronald, Kobbe, Robin, Nörz, Dominik, Schmiedel, Stefan, Grundhoff, Adam, Olearo, Flaminia, Emmerich, Petra, Robitaille, Alexis, Günther, Thomas, Braun, Platon, Andersen, Gabriele, Knobloch, Johannes K, Addo, Marylyn M, Lohse, Ansgar W, Aepfelbacher, Martin, Fischer, Nicole, Schulze Zur Wiesch, Julian, Lütgehetmann, Marc
Published in Viruses (12.04.2021)
Published in Viruses (12.04.2021)
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Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods
Asar, Lucia, Pfefferle, Susanne, Lütgehetmann, Marc, Hoffmann, Armin, Katchanov, Juri, Aepfelbacher, Martin, Rohde, Holger, Maurer, Florian P
Published in PloS one (06.06.2019)
Published in PloS one (06.06.2019)
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Wenzel, Jan, Lampe, Josephine, Müller-Fielitz, Helge, Schuster, Raphael, Zille, Marietta, Müller, Kristin, Krohn, Markus, Körbelin, Jakob, Zhang, Linlin, Özorhan, Ümit, Neve, Vanessa, Wagner, Julian U. G., Bojkova, Denisa, Shumliakivska, Mariana, Jiang, Yun, Fähnrich, Anke, Ott, Fabian, Sencio, Valentin, Robil, Cyril, Pfefferle, Susanne, Sauve, Florent, Coêlho, Caio Fernando Ferreira, Franz, Jonas, Spiecker, Frauke, Lembrich, Beate, Binder, Sonja, Feller, Nina, König, Peter, Busch, Hauke, Collin, Ludovic, Villaseñor, Roberto, Jöhren, Olaf, Altmeppen, Hermann C., Pasparakis, Manolis, Dimmeler, Stefanie, Cinatl, Jindrich, Püschel, Klaus, Zelic, Matija, Ofengeim, Dimitry, Stadelmann, Christine, Trottein, François, Nogueiras, Ruben, Hilgenfeld, Rolf, Glatzel, Markus, Prevot, Vincent, Schwaninger, Markus
Published in Nature neuroscience (01.11.2021)
Published in Nature neuroscience (01.11.2021)
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