The Witkop Cyclization: A Photoinduced CH Activation of the Indole System
Gritsch, Philipp J., Leitner, Christian, Pfaffenbach, Magnus, Gaich, Tanja
Published in Angewandte Chemie International Edition (27.01.2014)
Published in Angewandte Chemie International Edition (27.01.2014)
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Structural complexity through multicomponent cycloaddition cascades enabled by dual-purpose, reactivity regenerating 1,2,3-triene equivalents
Wender, Paul A., Fournogerakis, Dennis N., Jeffreys, Matthew S., Quiroz, Ryan V., Inagaki, Fuyuhiko, Pfaffenbach, Magnus
Published in Nature chemistry (01.05.2014)
Published in Nature chemistry (01.05.2014)
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Synthesis of Indolophanes by Photochemical Macrocyclization
Pfaffenbach, Magnus, Roller, Alexander, Gaich, Tanja
Published in Chemistry : a European journal (13.06.2016)
Published in Chemistry : a European journal (13.06.2016)
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Synthesis of N‑Substituted 3‑Amino-2-pyridones
Bolduc, Philippe N., Pfaffenbach, Magnus, Blasczak, Vanna D., Mathieu, Steven R., Peterson, Emily A.
Published in Organic letters (26.08.2022)
Published in Organic letters (26.08.2022)
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Total Syntheses of Xiamycins A, C, F, H and Oridamycin A and Preliminary Evaluation of their Anti‐Fungal Properties
Pfaffenbach, Magnus, Bakanas, Ian, O'Connor, Nicholas R., Herrick, Jessica L., Sarpong, Richmond
Published in Angewandte Chemie International Edition (21.10.2019)
Published in Angewandte Chemie International Edition (21.10.2019)
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The Discovery of 7‑Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)‑N‑(6-methylpyrazolo[1,5‑a]pyrimidin-3-yl)imidazo[1,2‑a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke
Evans, Ryan, Bolduc, Philippe N., Pfaffenbach, Magnus, Gao, Fang, May-Dracka, Tricia, Fang, Terry, Hopkins, Brian T., Chodaparambil, Jayanth V, Henry, Kate L., Li, Pei, Metrick, Claire, Nelson, Ashley, Trapa, Patrick, Thomas, Ankur, Burkly, Linda, Peterson, Emily A.
Published in Journal of medicinal chemistry (28.03.2024)
Published in Journal of medicinal chemistry (28.03.2024)
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Discovery of BIO-8169A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation
Pfaffenbach, Magnus, Bolduc, Philippe N., Xin, Zhili, Gao, Fang, Evans, Ryan, Fang, Terry, Chodaparambil, Jayanth V., Henry, Kate L., Li, Pei, Mathieu, Steven, Metrick, Claire, Vera Rebollar, Jorge A., Gu, Rong-Fang, Mccarl, Christie-Ann, Silbereis, John, Peterson, Emily A.
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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Journal Article
Propargyltrimethylsilanes as Allene Equivalents in Transition Metal-Catalyzed [5 + 2] Cycloadditions
Wender, Paul A, Inagaki, Fuyuhiko, Pfaffenbach, Magnus, Stevens, Matthew C
Published in Organic letters (06.06.2014)
Published in Organic letters (06.06.2014)
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Journal Article
IRAK4 억제제로서의 2H-인다졸 유도체 및 질환의 치료에서의그의 용도
PETERSON EMILY ANNE, EVANS RYAN, PFAFFENBACH MAGNUS, XIN ZHILI, BOLDUC PHILIPPE, GAO FANG
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent
IRAK4 억제제로서의 이미다조[1,2-A]피리딘 유도체및 질환의 치료에서의 그의 용도
PETERSON EMILY ANNE, EVANS RYAN, PFAFFENBACH MAGNUS, XIN ZHILI, BOLDUC PHILIPPE, GAO FANG
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent
The Witkop Cyclization: A Photoinduced CH Activation of the Indole System
Gritsch, Philipp J, Leitner, Christian, Pfaffenbach, Magnus, Gaich, Tanja
Published in Angewandte Chemie International Edition (27.01.2014)
Published in Angewandte Chemie International Edition (27.01.2014)
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Journal Article
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors
Bolduc, Philippe N., Pfaffenbach, Magnus, Evans, Ryan, Xin, Zhili, Henry, Kate L., Gao, Fang, Fang, Terry, Silbereis, John, Vera Rebollar, Jorge, Li, Pei, Chodaparambil, Jayanth V, Metrick, Claire, Peterson, Emily A.
Published in ACS medicinal chemistry letters (09.05.2024)
Published in ACS medicinal chemistry letters (09.05.2024)
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Journal Article
2H-이미다졸 유도체 및 질환 치료에서 그의 용도
PETERSON EMILY ANNE, EVANS RYAN, PFAFFENBACH MAGNUS, XIN ZHILI, BOLDUC PHILIPPE, GAO FANG
Year of Publication 04.04.2022
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Year of Publication 04.04.2022
Patent
이미다조[1,2-a]피리디닐 유도체 및 질병의 치료에서 이것들의 용도
PETERSON EMILY ANNE, EVANS RYAN, PFAFFENBACH MAGNUS, XIN ZHILI, BOLDUC PHILIPPE, GAO FANG, MAY DRACKA TRICIA
Year of Publication 07.03.2022
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Year of Publication 07.03.2022
Patent
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Rong, Jiawei, Pellegrini, Tilde, Harutyunyan, Syuzanna R., Šponer, Judit E., Šponer, Jiří, Nováková, Olga, Brabec, Viktor, Šedo, Ondrej, Zdráhal, Zbyněk, Costanzo, Giovanna, Pino, Samanta, Saladino, Raffaele, Di Mauro, Ernesto, Kamalov, Meder, Kaur, Harveen, Brimble, Margaret A., Papadimitriou, Sofia A., Salinas, Yolanda, Resmini, Marina, Xie, Junfeng, Xie, Yi, Sazonov, Petr K., Beletskaya, Irina P., Pfaffenbach, Magnus, Gaich, Tanja, Meninno, Sara, Lattanzi, Alessandra
Published in Chemistry : a European journal (07.03.2016)
Published in Chemistry : a European journal (07.03.2016)
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