Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation
Peviani, Marco, Salvaneschi, Eleonora, Bontempi, Leonardo, Petese, Alessandro, Manzo, Antonio, Rossi, Daniela, Salmona, Mario, Collina, Simona, Bigini, Paolo, Curti, Daniela
Published in Neurobiology of disease (01.02.2014)
Published in Neurobiology of disease (01.02.2014)
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Journal Article
Therapeutic efficacy of intracerebral hematopoietic stem cell gene therapy in an Alzheimer’s disease mouse model
Milazzo, Rita, Montepeloso, Annita, Kumar, Rajesh, Ferro, Francesca, Cavalca, Eleonora, Rigoni, Pietro, Cabras, Paolo, Ciervo, Yuri, Das, Sabyasachi, Capotondo, Alessia, Pellin, Danilo, Peviani, Marco, Biffi, Alessandra
Published in Nature communications (13.09.2024)
Published in Nature communications (13.09.2024)
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Journal Article
Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma
Peviani, Marco, Spano, Giorgia, Pagani, Antonella, Brugnara, Gianluca, Covino, Cesare, Galli, Rossella, Biffi, Alessandra, Politi, Letterio S.
Published in Scientific reports (21.10.2020)
Published in Scientific reports (21.10.2020)
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Journal Article
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
Peviani, Marco, Das, Sabyasachi, Patel, Janki, Jno‐Charles, Odella, Kumar, Rajesh, Zguro, Ana, Mathews, Tyler D, Cabras, Paolo, Milazzo, Rita, Cavalca, Eleonora, Poletti, Valentina, Biffi, Alessandra
Published in EMBO molecular medicine (11.04.2023)
Published in EMBO molecular medicine (11.04.2023)
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Journal Article
Heterogeneity of Neuroinflammatory Responses in Amyotrophic Lateral Sclerosis: A Challenge or an Opportunity?
Cipollina, Giada, Davari Serej, Arash, Di Nolfi, Gianluca, Gazzano, Andrea, Marsala, Andrea, Spatafora, Mauro G, Peviani, Marco
Published in International journal of molecular sciences (25.10.2020)
Published in International journal of molecular sciences (25.10.2020)
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Journal Article
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System
Meneghini, Vasco, Peviani, Marco, Luciani, Marco, Zambonini, Giada, Gritti, Angela
Published in Frontiers in genome editing (03.03.2021)
Published in Frontiers in genome editing (03.03.2021)
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Journal Article
Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration
De Paola, Massimiliano, Mariani, Alessandro, Bigini, Paolo, Peviani, Marco, Ferrara, Giovanni, Molteni, Monica, Gemma, Sabrina, Veglianese, Pietro, Castellaneta, Valeria, Boldrin, Valentina, Rossetti, Carlo, Chiabrando, Chiara, Forloni, Gianluigi, Mennini, Tiziana, Fanelli, Roberto
Published in Molecular medicine (Cambridge, Mass.) (01.06.2012)
Published in Molecular medicine (Cambridge, Mass.) (01.06.2012)
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Journal Article
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain
Rossino, Giacomo, Marra, Annamaria, Listro, Roberta, Peviani, Marco, Poggio, Elena, Curti, Daniela, Pellavio, Giorgia, Laforenza, Umberto, Dondio, Giulio, Schepmann, Dirk, Wünsch, Bernhard, Bedeschi, Martina, Marino, Noemi, Tesei, Anna, Ha, Hee-Jin, Kim, Young-Ho, Ann, Jihyae, Lee, Jeewoo, Linciano, Pasquale, Di Giacomo, Marcello, Rossi, Daniela, Collina, Simona
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
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Journal Article
Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-Scale synthesis, physicochemical characterization and in vitro metabolic stability
Rossi, Daniela, Marra, Annamaria, Picconi, Pietro, Serra, Massimo, Catenacci, Laura, Sorrenti, Milena, Laurini, Erik, Fermeglia, Maurizio, Pricl, Sabrina, Brambilla, Stefania, Almirante, Nicoletta, Peviani, Marco, Curti, Daniela, Collina, Simona
Published in Bioorganic & medicinal chemistry (01.05.2013)
Published in Bioorganic & medicinal chemistry (01.05.2013)
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Journal Article
Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC-33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists
Rossi, Daniela, Pedrali, Alice, Gaggeri, Raffaella, Marra, Annamaria, Pignataro, Luca, Laurini, Erik, Dal Col, Valentina, Fermeglia, Maurizio, Pricl, Sabrina, Schepmann, Dirk, Wünsch, Bernhard, Peviani, Marco, Curti, Daniela, Collina, Simona
Published in ChemMedChem (01.09.2013)
Published in ChemMedChem (01.09.2013)
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Journal Article
Synthesis and Characterization of a “Clickable” PBR28 TSPO-Selective Ligand Derivative Suitable for the Functionalization of Biodegradable Polymer Nanoparticles
Auriemma, Renato, Sponchioni, Mattia, Capasso Palmiero, Umberto, Rossino, Giacomo, Rossetti, Arianna, Marsala, Andrea, Collina, Simona, Sacchetti, Alessandro, Moscatelli, Davide, Peviani, Marco
Published in Nanomaterials (Basel, Switzerland) (28.06.2021)
Published in Nanomaterials (Basel, Switzerland) (28.06.2021)
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Journal Article
Increased axonal ribosome numbers is an early event in the pathogenesis of amyotrophic lateral sclerosis
Verheijen, Mark H G, Peviani, Marco, Hendricusdottir, Rita, Bell, Erin M, Lammens, Martin, Smit, August B, Bendotti, Caterina, van Minnen, Jan
Published in PloS one (30.01.2014)
Published in PloS one (30.01.2014)
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Journal Article
Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells
Rossi, Daniela, Pedrali, Alice, Urbano, Mariangela, Gaggeri, Raffaella, Serra, Massimo, Fernández, Leyden, Fernández, Michael, Caballero, Julio, Ronsisvalle, Simone, Prezzavento, Orazio, Schepmann, Dirk, Wuensch, Bernhard, Peviani, Marco, Curti, Daniela, Azzolina, Ornella, Collina, Simona
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
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Journal Article
Biodegradable polymeric nanoparticles administered in the cerebrospinal fluid: Brain biodistribution, preferential internalization in microglia and implications for cell-selective drug release
Peviani, Marco, Capasso Palmiero, Umberto, Cecere, Francesca, Milazzo, Rita, Moscatelli, Davide, Biffi, Alessandra
Published in Biomaterials (01.07.2019)
Published in Biomaterials (01.07.2019)
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Journal Article
Selective Nanovector Mediated Treatment of Activated Proinflammatory Microglia/Macrophages in Spinal Cord Injury
Papa, Simonetta, Rossi, Filippo, Ferrari, Raffaele, Mariani, Alessandro, De Paola, Massimiliano, Caron, Ilaria, Fiordaliso, Fabio, Bisighini, Cinzia, Sammali, Eliana, Colombo, Claudio, Gobbi, Marco, Canovi, Mara, Lucchetti, Jacopo, Peviani, Marco, Morbidelli, Massimo, Forloni, Gianluigi, Perale, Giuseppe, Moscatelli, Davide, Veglianese, Pietro
Published in ACS nano (26.11.2013)
Published in ACS nano (26.11.2013)
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Journal Article
Hydrazone linked doxorubicin-PLA prodrug nanoparticles with high drug loading
Gatti, Simone, Agostini, Azzurra, Palmiero, Umberto Capasso, Colombo, Claudio, Peviani, Marco, Biffi, Alessandra, Moscatelli, Davide
Published in Nanotechnology (27.07.2018)
Published in Nanotechnology (27.07.2018)
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Journal Article
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents
Linciano, Pasquale, Sorbi, Claudia, Rossino, Giacomo, Rossi, Daniela, Marsala, Andrea, Denora, Nunzio, Bedeschi, Martina, Marino, Noemi, Miserocchi, Giacomo, Dondio, Giulio, Peviani, Marco, Tesei, Anna, Collina, Simona, Franchini, Silvia
Published in European journal of medicinal chemistry (05.03.2023)
Published in European journal of medicinal chemistry (05.03.2023)
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Journal Article
Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury
Papa, Simonetta, Ferrari, Raffaele, De Paola, Massimiliano, Rossi, Filippo, Mariani, Alessandro, Caron, Ilaria, Sammali, Eliana, Peviani, Marco, Dell'Oro, Valentina, Colombo, Claudio, Morbidelli, Massimo, Forloni, Gianluigi, Perale, Giuseppe, Moscatelli, Davide, Veglianese, Pietro
Published in Journal of controlled release (28.01.2014)
Published in Journal of controlled release (28.01.2014)
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