CDK inhibitors in cancer therapy: what is next?
Malumbres, Marcos, Pevarello, Paolo, Barbacid, Mariano, Bischoff, James R
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2008)
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2008)
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Journal Article
Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model
Apolloni, Savina, Fabbrizio, Paola, Amadio, Susanna, Napoli, Giulia, Freschi, Mattia, Sironi, Francesca, Pevarello, Paolo, Tarroni, Paola, Liberati, Chiara, Bendotti, Caterina, Volonté, Cinzia
Published in International journal of molecular sciences (01.10.2021)
Published in International journal of molecular sciences (01.10.2021)
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Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases
Link, Wolfgang, Oyarzabal, Julen, Serelde, Beatriz G., Albarran, Maria Isabel, Rabal, Obdulia, Cebriá, Antonio, Alfonso, Patricia, Fominaya, Jesus, Renner, Oliver, Peregrina, Sandra, Soilán, David, Ceballos, Plácido A., Hernández, Ana-Isabel, Lorenzo, Milagros, Pevarello, Paolo, Granda, Teresa G., Kurz, Guido, Carnero, Amancio, Bischoff, James R.
Published in The Journal of biological chemistry (09.10.2009)
Published in The Journal of biological chemistry (09.10.2009)
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Journal Article
Optimization of 6,6-dimethyl pyrrolo[3,4- c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing
Brasca, Maria Gabriella, Albanese, Clara, Alzani, Rachele, Amici, Raffaella, Avanzi, Nilla, Ballinari, Dario, Bischoff, James, Borghi, Daniela, Casale, Elena, Croci, Valter, Fiorentini, Francesco, Isacchi, Antonella, Mercurio, Ciro, Nesi, Marcella, Orsini, Paolo, Pastori, Wilma, Pesenti, Enrico, Pevarello, Paolo, Roussel, Patrick, Varasi, Mario, Volpi, Daniele, Vulpetti, Anna, Ciomei, Marina
Published in Bioorganic & medicinal chemistry (01.03.2010)
Published in Bioorganic & medicinal chemistry (01.03.2010)
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Journal Article
Fragment-hopping-based discovery of a novel chemical series of proto-oncogene PIM-1 kinase inhibitors
Saluste, Gustavo, Albarran, Maria I, Alvarez, Rosa M, Rabal, Obdulia, Ortega, Miguel Angel, Blanco, Carmen, Kurz, Guido, Salgado, Antonio, Pevarello, Paolo, Bischoff, James R, Pastor, Joaquin, Oyarzabal, Julen
Published in PloS one (24.10.2012)
Published in PloS one (24.10.2012)
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Journal Article
3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization
Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro
Published in Journal of medicinal chemistry (21.04.2005)
Published in Journal of medicinal chemistry (21.04.2005)
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Journal Article
Synthesis and Anticonvulsant Activity of a New Class of 2-[(Arylalkyl)amino]alkanamide Derivatives
Pevarello, Paolo, Bonsignori, Alberto, Dostert, Philippe, Heidempergher, Franco, Pinciroli, Vittorio, Colombo, Maristella, McArthur, Robert A, Salvati, Patricia, Post, Claes, Fariello, Ruggero G, Varasi, Mario
Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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PNU-151774E protects against kainate-induced status epilepticus and hippocampal lesions in the rat
Maj, Roberto, Fariello, Ruggero G, Ukmar, Giorgio, Varasi, Mario, Pevarello, Paolo, McArthur, Robert A, Salvati, Patricia
Published in European journal of pharmacology (16.10.1998)
Published in European journal of pharmacology (16.10.1998)
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Journal Article
P2X7 antagonists for CNS indications: recent patent disclosures
Pevarello, Paolo, Bovolenta, Silvia, Tarroni, Paola, Za, Lorena, Severi, Elda, Torino, Domenica, Vitalone, Rocco
Published in Pharmaceutical patent analyst (01.03.2017)
Published in Pharmaceutical patent analyst (01.03.2017)
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Journal Article
Identification of N,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor
Brasca, Maria Gabriella, Amboldi, Nadia, Ballinari, Dario, Cameron, Alexander, Casale, Elena, Cervi, Giovanni, Colombo, Maristella, Colotta, Francesco, Croci, Valter, D’Alessio, Roberto, Fiorentini, Francesco, Isacchi, Antonella, Mercurio, Ciro, Moretti, Walter, Panzeri, Achille, Pastori, Wilma, Pevarello, Paolo, Quartieri, Francesca, Roletto, Fulvia, Traquandi, Gabriella, Vianello, Paola, Vulpetti, Anna, Ciomei, Marina
Published in Journal of medicinal chemistry (27.08.2009)
Published in Journal of medicinal chemistry (27.08.2009)
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Journal Article
바이시클릭 CX3CR1 수용체 작용제
LIGHTFOOT YAIMA LUZARDO, TORINO DOMENICA, PISCITELLI FRANCESCO, BOVOLENTA SILVIA, CUSANO VALENTINA, PEVARELLO PAOLO, RAY WILLIAM, JONES PHILIP, HAMBY MARY, LIBERATI CHIARA, THOMAS RUSSELL, YOUSIF ALI
Year of Publication 29.06.2022
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Year of Publication 29.06.2022
Patent
Differentiation between [1,2,4]triazolo[1,5-a] pyrimidine and [1,2,4]triazolo[4,3-a]- pyrimidine regioisomers by 1H15N HMBC experiments
Salgado, Antonio, Varela, Carmen, García Collazo, Ana María, Pevarello, Paolo
Published in Magnetic resonance in chemistry (01.08.2010)
Published in Magnetic resonance in chemistry (01.08.2010)
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Journal Article
Identification of Potent Pyrazolo[4,3-h]quinazoline-3-carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors
Traquandi, Gabriella, Ciomei, Marina, Ballinari, Dario, Casale, Elena, Colombo, Nicoletta, Croci, Valter, Fiorentini, Francesco, Isacchi, Antonella, Longo, Antonio, Mercurio, Ciro, Panzeri, Achille, Pastori, Wilma, Pevarello, Paolo, Volpi, Daniele, Roussel, Patrick, Vulpetti, Anna, Brasca, Maria Gabriella
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Journal Article
Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition
Blanco-Aparicio, Carmen, Collazo, Ana María García, Oyarzabal, Julen, Leal, Juan F, Albarán, María Isabel, Lima, Francisco Ramos, Pequeño, Belén, Ajenjo, Nuria, Becerra, Mercedes, Alfonso, Patricia, Reymundo, María Isabel, Palacios, Irene, Mateos, Genoveva, Quiñones, Helena, Corrionero, Ana, Carnero, Amancio, Pevarello, Paolo, Lopez, Ana Rodríguez, Fominaya, Jesús, Pastor, Joaquín, Bischoff, James R
Published in Cancer letters (28.01.2011)
Published in Cancer letters (28.01.2011)
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Journal Article
Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water
Dalvit, C, Pevarello, P, Tatò, M, Veronesi, M, Vulpetti, A, Sundström, M
Published in Journal of biomolecular NMR (01.09.2000)
Published in Journal of biomolecular NMR (01.09.2000)
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Journal Article
Kinase inhibitors for CNS diseases: an analysis of the recent patent literature
Amigoni, Federica, Legnaghi, Elena, Pevarello, Paolo
Published in Pharmaceutical patent analyst (01.05.2012)
Published in Pharmaceutical patent analyst (01.05.2012)
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