Oncolytic Adenoviruses for the Treatment of Human Cancer: Focus on Translational and Clinical Data
Pesonen, Sari, Kangasniemi, Lotta, Hemminki, Akseli
Published in Molecular pharmaceutics (07.02.2011)
Published in Molecular pharmaceutics (07.02.2011)
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Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 - Support for clinical studies on advanced cancer treatment
Kuryk, Lukasz, Vassilev, Lotta, Ranki, Tuuli, Hemminki, Akseli, Karioja-Kallio, Aila, Levälampi, Onerva, Vuolanto, Antti, Cerullo, Vincenzo, Pesonen, Sari
Published in PloS one (10.08.2017)
Published in PloS one (10.08.2017)
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Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity
Strauss, Robert, Li, Zong-Yi, Liu, Ying, Beyer, Ines, Persson, Jonas, Sova, Pavel, Möller, Thomas, Pesonen, Sari, Hemminki, Akseli, Hamerlik, Petra, Drescher, Charles, Urban, Nicole, Bartek, Jiri, Lieber, André
Published in PloS one (14.01.2011)
Published in PloS one (14.01.2011)
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Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
DIACONU, Lulia, CERULLO, Vincenzo, ELIOPOULOS, Aristides G, PESONEN, Sari, HEMMINKI, Akseli, HIRVINEN, Mari L. M, ESCUTENAIRE, Sophie, UGOLINI, Matteo, PESONEN, Saila K, BRAMANTE, Simona, PARVIAINEN, Suvi, KANERVA, Anna, LOSKOG, Angelica S. I
Published in Cancer research (Chicago, Ill.) (01.05.2012)
Published in Cancer research (Chicago, Ill.) (01.05.2012)
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Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients
CERULLO, Vincenzo, PESONEN, Sari, RAJECKI, Maria, KANGASNIEMI, Lotta, GUSE, Kilian, HELMINEN, Andreas, AHTIAINEN, Laura, RISTIMÄKI, Ari, RÄISÄNEN-SOKOLOWSKI, Anne, HAAVISTO, Elina, OKSANEN, Minna, KARLI, Eerika, DIACONU, Lulia, KARIOJA-KALLIO, Aila, HOLM, Sirkka-Liisa, KOURI, Mauri, JOENSUU, Timo, KANERVA, Anna, HEMMINKI, Akseli, ESCUTENAIRE, Sophie, ARSTILA, Petteri T, UGOLINI, Matteo, NOKISALMI, Petri, RAKI, Mari, LAASONEN, Leena, SÄRKIOJA, Merja
Published in Cancer research (Chicago, Ill.) (01.06.2010)
Published in Cancer research (Chicago, Ill.) (01.06.2010)
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A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines
Feola, Sara, Chiaro, Jacopo, Martins, Beatriz, Russo, Salvatore, Fusciello, Manlio, Ylösmäki, Erkko, Bonini, Chiara, Ruggiero, Eliana, Hamdan, Firas, Feodoroff, Michaela, Antignani, Gabriella, Viitala, Tapani, Pesonen, Sari, Grönholm, Mikaela, Branca, Rui M M, Lehtiö, Janne, Cerullo, Vincenzo
Published in eLife (22.03.2022)
Published in eLife (22.03.2022)
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Journal Article
Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks
Kuryk, Lukasz, Møller, Anne-Sophie W, Vuolanto, Antti, Pesonen, Sari, Garofalo, Mariangela, Cerullo, Vincenzo, Jaderberg, Magnus
Published in International journal of molecular sciences (31.01.2019)
Published in International journal of molecular sciences (31.01.2019)
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Peptides-Coated Oncolytic Vaccines for Cancer Personalized Medicine
Feola, Sara, Russo, Salvatore, Martins, Beatriz, Lopes, Alessandra, Vandermeulen, Gaëlle, Fluhler, Vinciane, De Giorgi, Camilla, Fusciello, Manlio, Pesonen, Sari, Ylösmäki, Erkko, Antignani, Gabriella, Chiaro, Jacopo, Hamdan, Firas, Feodoroff, Michaela, Grönholm, Mikaela, Cerullo, Vincenzo
Published in Frontiers in immunology (14.04.2022)
Published in Frontiers in immunology (14.04.2022)
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Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors
Feola, Sara, Hamdan, Firas, Russo, Salvatore, Chiaro, Jacopo, Fusciello, Manlio, Feodoroff, Michaela, Antignani, Gabriella, D'Alessio, Federica, Mölsä, Riikka, Stigzelius, Virpi, Bottega, Paolo, Pesonen, Sari, Leusen, Jeanette, Grönholm, Mikaela, Cerullo, Vincenzo
Published in Journal for immunotherapy of cancer (08.03.2024)
Published in Journal for immunotherapy of cancer (08.03.2024)
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Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform
Ylösmäki, Erkko, Ylösmäki, Leena, Fusciello, Manlio, Martins, Beatriz, Ahokas, Petra, Cojoc, Hanne, Uoti, Arttu, Feola, Sara, Kreutzman, Anna, Ranki, Tuuli, Karbach, Julia, Viitala, Tapani, Priha, Petri, Jäger, Elke, Pesonen, Sari, Cerullo, Vincenzo
Published in Molecular therapy. Oncolytics (26.03.2021)
Published in Molecular therapy. Oncolytics (26.03.2021)
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Serotype chimeric oncolytic adenovirus coding for GM‐CSF for treatment of sarcoma in rodents and humans
Bramante, Simona, Koski, Anniina, Kipar, Anja, Diaconu, Iulia, Liikanen, Ilkka, Hemminki, Otto, Vassilev, Lotta, Parviainen, Suvi, Cerullo, Vincenzo, Pesonen, Saila K, Oksanen, Minna, Heiskanen, Raita, Rouvinen‐Lagerström, Noora, Merisalo‐Soikkeli, Maiju, Hakonen, Tiina, Joensuu, Timo, Kanerva, Anna, Pesonen, Sari, Hemminki, Akseli
Published in International journal of cancer (01.08.2014)
Published in International journal of cancer (01.08.2014)
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Antiangiogenic Arming of an Oncolytic Vaccinia Virus Enhances Antitumor Efficacy in Renal Cell Cancer Models
Guse, Kilian, Sloniecka, Marta, Diaconu, Iulia, Ottolino-Perry, Kathryn, Tang, Nan, Ng, Calvin, Le Boeuf, Fabrice, Bell, John C, McCart, J Andrea, Ristimäki, Ari, Pesonen, Sari, Cerullo, Vincenzo, Hemminki, Akseli
Published in Journal of Virology (01.01.2010)
Published in Journal of Virology (01.01.2010)
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Incomplete but infectious vaccinia virions are produced in the absence of oncolysis in feline SCCF1 cells
Parviainen, Suvi, Autio, Karoliina, Vähä-Koskela, Markus, Guse, Kilian, Pesonen, Sari, Rosol, Thomas J, Zhao, Fang, Hemminki, Akseli
Published in PloS one (23.03.2015)
Published in PloS one (23.03.2015)
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Optimized mouse model for the imaging of tumor metastasis upon experimental therapy
Lavilla-Alonso, Sergio, Abo-Ramadan, Usama, Halavaara, Juha, Escutenaire, Sophie, Tatlisumak, Turgut, Saksela, Kalle, Kanerva, Anna, Hemminki, Akseli, Pesonen, Sari
Published in PloS one (03.11.2011)
Published in PloS one (03.11.2011)
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Journal Article
Switching the fiber knob of oncolytic adenoviruses to avoid neutralizing antibodies in human cancer patients
Raki, Mari, Sarkioja, Merja, Escutenaire, Sophie, Kangasniemi, Lotta, Haavisto, Elina, Kanerva, Anna, Cerullo, Vincenzo, Joensuu, Timo, Oksanen, Minna, Pesonen, Sari, Hemminki, Akseli
Published in The journal of gene medicine (01.05.2011)
Published in The journal of gene medicine (01.05.2011)
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A Phase I/II Trial of Gefitinib Given Concurrently With Radiotherapy in Patients With Nonmetastatic Prostate Cancer
Joensuu, Greetta, B.M, Joensuu, Timo, M.D., Ph.D, Nokisalmi, Petri, M.Sc., B.M, Reddy, Chandana, M.Sc, Isola, Jorma, M.D., Ph.D, Ruutu, Mirja, M.D., Ph.D, Kouri, Mauri, M.D., Ph.D, Kupelian, Patrick A., M.D, Collan, Juhani, M.D, Pesonen, Sari, Ph.D, Hemminki, Akseli, M.D., Ph.D
Published in International journal of radiation oncology, biology, physics (01.09.2010)
Published in International journal of radiation oncology, biology, physics (01.09.2010)
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Radiation-Induced Upregulation of Gene Expression From Adenoviral Vectors Mediated by DNA Damage Repair and Regulation
Nokisalmi, Petri, M.D., M.Sc, Rajecki, Maria, M.D., Ph.D, Pesonen, Sari, Ph.D, Escutenaire, Sophie, D.V.M., Ph.D, Soliymani, Rabah, M.Sc, Tenhunen, Mikko, Ph.D, Ahtiainen, Laura, Ph.D, Hemminki, Akseli, M.D., Ph.D
Published in International journal of radiation oncology, biology, physics (01.05.2012)
Published in International journal of radiation oncology, biology, physics (01.05.2012)
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Effects of in utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) on rat follicular steroidogenesis
Pesonen, Sari A., Haavisto, Tapio E., Viluksela, Matti, Toppari, Jorma, Paranko, Jorma
Published in Reproductive toxicology (Elmsford, N.Y.) (01.10.2006)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.10.2006)
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Journal Article
Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5
Ahonen, Marko T, Diaconu, Iulia, Pesonen, Sari, Kanerva, Anna, Baumann, Marc, Parviainen, Suvi T, Spiller, Brad, Cerullo, Vincenzo, Hemminki, Akseli
Published in PloS one (30.09.2010)
Published in PloS one (30.09.2010)
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Adenoviral E4orf3 and E4orf6 Proteins, But Not E1B55K, Increase Killing of Cancer Cells by Radiotherapy in vivo
Liikanen, Ilkka, B.M, Dias, João D., M.Sc, Nokisalmi, Petri, B.M., M.Sc, Sloniecka, Marta, M.Sc, Kangasniemi, Lotta, Ph.D, Rajecki, Maria, M.D, Dobner, Thomas, Ph.D, Tenhunen, Mikko, Ph.D, Kanerva, Anna, M.D., Ph.D, Pesonen, Sari, Ph.D, Ahtiainen, Laura, Ph.D, Hemminki, Akseli, M.D., Ph.D
Published in International journal of radiation oncology, biology, physics (15.11.2010)
Published in International journal of radiation oncology, biology, physics (15.11.2010)
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