Direct α-Functionalization of Saturated Cyclic Amines
Mitchell, Emily A., Peschiulli, Aldo, Lefevre, Nicolas, Meerpoel, Lieven, Maes, Bert U. W.
Published in Chemistry : a European journal (13.08.2012)
Published in Chemistry : a European journal (13.08.2012)
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Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ‑Fluoroamines
Roagna, Giulia, Ascough, David M. H, Ibba, Francesco, Vicini, Anna Chiara, Fontana, Alberto, Christensen, Kirsten E, Peschiulli, Aldo, Oehlrich, Daniel, Misale, Antonio, Trabanco, Andrés A, Paton, Robert S, Pupo, Gabriele, Gouverneur, Véronique
Published in Journal of the American Chemical Society (19.08.2020)
Published in Journal of the American Chemical Society (19.08.2020)
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The immobilisation of chiral organocatalysts on magnetic nanoparticles: the support particle cannot always be considered inert
Gleeson, Oliver, Davies, Gemma-Louise, Peschiulli, Aldo, Tekoriute, Renata, Gun'ko, Yurii K., Connon, Stephen J.
Published in Organic & biomolecular chemistry (26.10.2011)
Published in Organic & biomolecular chemistry (26.10.2011)
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Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid
Meyer, Claudio F., Hell, Sandrine M., Sap, Jeroen B.I., Misale, Antonio, Peschiulli, Aldo, Oehlrich, Daniel, Trabanco, Andrés A., Gouverneur, Véronique
Published in Tetrahedron (22.11.2019)
Published in Tetrahedron (22.11.2019)
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Ruthenium-Catalyzed α-(Hetero)Arylation of Saturated Cyclic Amines: Reaction Scope and Mechanism
Peschiulli, Aldo, Smout, Veerle, Storr, Thomas E., Mitchell, Emily A., Eliáš, Zdeněk, Herrebout, Wouter, Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W.
Published in Chemistry : a European journal (29.07.2013)
Published in Chemistry : a European journal (29.07.2013)
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Modulating physicochemical properties of tetrahydropyridine-2-amine BACE1 inhibitors with electron-withdrawing groups: A systematic study
Rombouts, Frederik J.R., Hsiao, Chien-Chi, Bache, Solène, De Cleyn, Michel, Heckmann, Pauline, Leenaerts, Jos, Martinéz-Lamenca, Carolina, Van Brandt, Sven, Peschiulli, Aldo, Vos, Ann, Gijsen, Harrie J.M.
Published in European journal of medicinal chemistry (15.01.2022)
Published in European journal of medicinal chemistry (15.01.2022)
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Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL‑1
Demin, Samuël, Peschiulli, Aldo, Velter, Adriana I., Vos, Ann, De Boeck, Benoît, Miller, Bradley, Rombouts, Frederik J. R., Reuillon, Tristan, Lento, William, Blanco, Maria Dominguez, Jouffroy, Matthieu, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Attar, Ricardo, Philippar, Ulrike
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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Removal of the Pyridine Directing Group from α‑Substituted N‑(Pyridin-2-yl)piperidines Obtained via Directed Ru-Catalyzed sp3 C–H Functionalization
Smout, Veerle, Peschiulli, Aldo, Verbeeck, Stefan, Mitchell, Emily A, Herrebout, Wouter, Bultinck, Patrick, Vande Velde, Christophe M. L, Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W
Published in Journal of organic chemistry (04.10.2013)
Published in Journal of organic chemistry (04.10.2013)
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MCL-1의 억제제로서의 거대환식 인돌 유도체
ROMBOUTS FREDERIK JAN RITA, VELTER ADRIANA INGRID, VOS ANN MARLEEN, REUILLON TRISTAN, PESCHIULLI ALDO
Year of Publication 25.10.2022
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Year of Publication 25.10.2022
Patent
MCL-1의 억제제로서의 N-연결된 마크로사이클릭 7--인돌 유도체
ROMBOUTS FREDERIK JAN RITA, DE BOECK BENOIT CHRISTIAN ALBERT GHISLAIN, VELTER ADRIANA INGRID, PESCHIULLI ALDO
Year of Publication 24.02.2023
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Year of Publication 24.02.2023
Patent
Evaluation of a Series of β‑Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads
Oehlrich, Daniel, Peschiulli, Aldo, Tresadern, Gary, Van Gool, Michiel, Vega, Juan Antonio, De Lucas, Ana Isabel, Alonso de Diego, Sergio A, Prokopcova, Hana, Austin, Nigel, Van Brandt, Sven, Surkyn, Michel, De Cleyn, Michel, Vos, Ann, Rombouts, Frederik J. R, Macdonald, Gregor, Moechars, Dieder, Gijsen, Harrie J. M, Trabanco, Andrés A
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo
Peschiulli, Aldo, Oehlrich, Daniel, Van Gool, Michiel, Austin, Nigel, Van Brandt, Sven, Surkyn, Michel, De Cleyn, Michel, Vos, Ann, Tresadern, Gary, Rombouts, Frederik J. R, Macdonald, Gregor J, Moechars, Diederik, Trabanco, Andrés A, Gijsen, Harrie J. M
Published in ACS medicinal chemistry letters (13.01.2022)
Published in ACS medicinal chemistry letters (13.01.2022)
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Journal Article
Direct [alpha]-Functionalization of Saturated Cyclic Amines
Mitchell, Emily A, Peschiulli, Aldo, Lefevre, Nicolas, Meerpoel, Lieven, Maes, Bert U W
Published in Chemistry : a European journal (13.08.2012)
Published in Chemistry : a European journal (13.08.2012)
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Journal Article
Abstract 2133: In pursuit of MCL-1 inhibitors with improved therapeutic window for the treatment of hematological malignancies: Discovery of JNJ-4355
Rombouts, Frederik J., William, Lento, Velter, Ingrid, Vos, Ann, Peschiulli, Aldo, Tristan, Reuillon, Blanco, Maria Dominguez, Jouffroy, Matthieu, McQueen, Lisa, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Walker, David, Packman, Kathryn, Bueters, Ruud, Vinken, Petra, Johnson, Amy, Attar, Ricardo, Philippar, Ulrike
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Removal of the Pyridine Directing Group from α-Substituted N -(Pyridin-2-yl)piperidines Obtained via Directed Ru-Catalyzed sp 3 C–H Functionalization
Smout, Veerle, Peschiulli, Aldo, Verbeeck, Stefan, Mitchell, Emily A., Herrebout, Wouter, Bultinck, Patrick, Vande Velde, Christophe M. L., Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W.
Published in Journal of organic chemistry (04.10.2013)
Published in Journal of organic chemistry (04.10.2013)
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Journal Article