The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor
Perzborn, Elisabeth, Roehrig, Susanne, Straub, Alexander, Kubitza, Dagmar, Misselwitz, Frank
Published in Nature reviews. Drug discovery (01.01.2011)
Published in Nature reviews. Drug discovery (01.01.2011)
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Rivaroxaban: A New Oral Factor Xa Inhibitor
Perzborn, Elisabeth, Roehrig, Susanne, Straub, Alexander, Kubitza, Dagmar, Mueck, Wolfgang, Laux, Volker
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
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Assessment of laboratory assays to measure rivaroxaban--an oral, direct factor Xa inhibitor
Samama, Meyer Michel, Martinoli, Jean-Luc, LeFlem, Léna, Guinet, Céline, Plu-Bureau, Geneviève, Depasse, François, Perzborn, Elisabeth
Published in Thrombosis and haemostasis (01.04.2010)
Published in Thrombosis and haemostasis (01.04.2010)
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Expression of pro-inflammatory genes in human endothelial cells: Comparison of rivaroxaban and dabigatran
Ellinghaus, Peter, Perzborn, Elisabeth, Hauenschild, Peter, Gerdes, Christoph, Heitmeier, Stefan, Visser, Mayken, Summer, Holger, Laux, Volker
Published in Thrombosis research (01.06.2016)
Published in Thrombosis research (01.06.2016)
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Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls
Samama, Meyer Michel, Contant, Genevieve, Spiro, Theodore E, Perzborn, Elisabeth, Guinet, Céline, Gourmelin, Yves, Le Flem, Léna, Rohde, Gabriele, Martinoli, Jean Luc
Published in Thrombosis and haemostasis (01.02.2012)
Published in Thrombosis and haemostasis (01.02.2012)
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Reversal of rivaroxaban anticoagulation by haemostatic agents in rats and primates
Perzborn, Elisabeth, Gruber, András, Tinel, Hanna, Marzec, Ulla M, Buetehorn, Ulf, Buchmueller, Anja, Heitmeier, Stefan, Laux, Volker
Published in Thrombosis and haemostasis (2013)
Published in Thrombosis and haemostasis (2013)
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Discovery of the Novel Antithrombotic Agent 5-Chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): An Oral, Direct Factor Xa Inhibitor
Roehrig, Susanne, Straub, Alexander, Pohlmann, Jens, Lampe, Thomas, Pernerstorfer, Josef, Schlemmer, Karl-Heinz, Reinemer, Peter, Perzborn, Elisabeth
Published in Journal of medicinal chemistry (22.09.2005)
Published in Journal of medicinal chemistry (22.09.2005)
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Laboratory assessment of rivaroxaban: a review
Samama, Meyer Michel, Contant, Geneviève, Spiro, Theodore E, Perzborn, Elisabeth, Le Flem, Lena, Guinet, Céline, Gourmelin, Yves, Rohde, Gabriele, Martinoli, Jean-Luc
Published in Thrombosis journal (03.07.2013)
Published in Thrombosis journal (03.07.2013)
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Journal Article
Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban
Varin, Rémi, Mirshahi, ShahSultan, Mirshahi, Pezhman, Klein, Christophe, Jamshedov, Jovid, Chidiac, Jean, Perzborn, Elisabeth, Mirshahi, Massoud, Soria, Claudine, Soria, Jeannette
Published in Thrombosis research (01.03.2013)
Published in Thrombosis research (01.03.2013)
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Direct inhibitors of coagulation proteins - the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy?
Laux, Volker, Perzborn, Elisabeth, Heitmeier, Stefan, von Degenfeld, Georges, Dittrich-Wengenroth, Elke, Buchmüller, Anja, Gerdes, Christoph, Misselwitz, Frank
Published in Thrombosis and haemostasis (01.11.2009)
Published in Thrombosis and haemostasis (01.11.2009)
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A role for coagulation factor Xa in experimental pulmonary arterial hypertension
Delbeck, Martina, Nickel, Katrin F., Perzborn, Elisabeth, Ellinghaus, Peter, Strassburger, Julia, Kast, Raimund, Laux, Volker, Schäfer, Stefan, Schermuly, Ralph T., von Degenfeld, Georges
Published in Cardiovascular research (01.10.2011)
Published in Cardiovascular research (01.10.2011)
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Rivaroxaban: a novel oral anticoagulant for the prevention and treatment of several thrombosis-mediated conditions
Sarich, Troy C., Peters, Gary, Berkowitz, Scott D., Misselwitz, Frank, Nessel, Christopher C., Burton, Paul, Cook-Bruns, Nancy, Lensing, Anthonie W.A., Haskell, Lloyd, Perzborn, Elisabeth, Kubitza, Dagmar, Moore, Kenneth T., Jalota, Sanjay, Weber, Juergen, Pan, Guohua, Sun, Xiang, Westermeier, Torsten, Nadel, Andrea, Oppenheimer, Leonard, DiBattiste, Peter M.
Published in Annals of the New York Academy of Sciences (01.07.2013)
Published in Annals of the New York Academy of Sciences (01.07.2013)
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Prevention and treatment of experimental thrombosis in rabbits with rivaroxaban (BAY 597939)--an oral, direct factor Xa inhibitor
Biemond, Bart J, Perzborn, Elisabeth, Friederich, Philip W, Levi, Marcel, Buetehorn, Ulf, Büller, Harry R
Published in Thrombosis and haemostasis (01.03.2007)
Published in Thrombosis and haemostasis (01.03.2007)
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Arterial antithrombotic activity of rivaroxaban, an orally active factor Xa inhibitor, in a rat electrolytic carotid artery injury model of thrombosis
Parry, Tom J, Huang, Zhihong, Chen, Cailin, Connelly, Margery A, Perzborn, Elisabeth, Andrade-Gordon, Patricia, Damiano, Bruce P
Published in Blood coagulation & fibrinolysis (01.12.2011)
Published in Blood coagulation & fibrinolysis (01.12.2011)
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Evaluation of the Prothrombin Time for Measuring Rivaroxaban Plasma Concentrations Using Calibrators and Controls
Samama Meyer Michel, Contant Genevieve, Spiro, Theodore E, Perzborn Elisabeth, Flem Lena Le, Guinet Céline, Gourmelin Yves, Martinoli, Jean Luc
Published in Clinical and applied thrombosis/hemostasis (01.04.2012)
Published in Clinical and applied thrombosis/hemostasis (01.04.2012)
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Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro
Perzborn, Elisabeth, Heitmeier, Stefan, Laux, Volker, Buchmüller, Anja
Published in Thrombosis research (01.04.2014)
Published in Thrombosis research (01.04.2014)
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Journal Article
Hemostatic Therapy in Experimental Intracerebral Hemorrhage Associated With Rivaroxaban
WEI ZHOU, ZORN, Markus, NAWROTH, Peter, BÜTEHORN, Ulf, PERZBORN, Elisabeth, HEITMEIER, Stefan, VELTKAMP, Roland
Published in Stroke (1970) (01.03.2013)
Published in Stroke (1970) (01.03.2013)
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Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR‐1 and PAR‐2
Morihara, Ryuta, Yamashita, Toru, Kono, Syoichiro, Shang, Jingwei, Nakano, Yumiko, Sato, Kota, Hishikawa, Nozomi, Ohta, Yasuyuki, Heitmeier, Stefan, Perzborn, Elisabeth, Abe, Koji
Published in Journal of neuroscience research (01.09.2017)
Published in Journal of neuroscience research (01.09.2017)
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