Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation
Taylor, Stephanie N, Morris, David H, Avery, Ann K, Workowski, Kimberly A, Batteiger, Byron E, Tiffany, Courtney A, Perry, Caroline R, Raychaudhuri, Aparna, Scangarella-Oman, Nicole E, Hossain, Mohammad, Dumont, Etienne F
Published in Clinical infectious diseases (01.08.2018)
Published in Clinical infectious diseases (01.08.2018)
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Dose Selection for Phase III Clinical Evaluation of Gepotidacin (GSK2140944) in the Treatment of Uncomplicated Urinary Tract Infections
Scangarella-Oman, Nicole E, Hossain, Mohammad, Hoover, Jennifer L, Perry, Caroline R, Tiffany, Courtney, Barth, Aline, Dumont, Etienne F
Published in Antimicrobial agents and chemotherapy (15.03.2022)
Published in Antimicrobial agents and chemotherapy (15.03.2022)
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Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials
Wagenlehner, Florian, Perry, Caroline R, Hooton, Thomas M, Scangarella-Oman, Nicole E, Millns, Helen, Powell, Marcy, Jarvis, Emily, Dennison, Jeremy, Sheets, Amanda, Butler, Deborah, Breton, John, Janmohamed, Salim
Published in The Lancet (British edition) (24.02.2024)
Published in The Lancet (British edition) (24.02.2024)
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Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis
Zou, Yongkang, Watters, Andrea, Cheng, Nan, Perry, Caroline E, Xu, Ke, Alicea, Gretchen M, Parris, Joshua L D, Baraban, Ezra, Ray, Pulak, Nayak, Anupma, Xu, Xiaowei, Herlyn, Meenhard, Murphy, Maureen E, Weeraratna, Ashani T, Schug, Zachary T, Chen, Qing
Published in Cancer discovery (01.12.2019)
Published in Cancer discovery (01.12.2019)
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Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy
Kopinski, Piotr K., Janssen, Kevin A., Schaefer, Patrick M., Trefely, Sophie, Perry, Caroline E., Potluri, Prasanth, Tintos-Hernandez, Jesus A., Singh, Larry N., Karch, Kelly R., Campbell, Sydney L., Doan, Mary T., Jiang, Helen, Nissim, Itzhak, Nakamaru-Ogiso, Eiko, Wellen, Kathryn E., Snyder, Nathaniel W., Garcia, Benjamin A., Wallace, Douglas C.
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2019)
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Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants With Uncomplicated Urinary Tract Infection (Acute Uncomplicated Cystitis)
Overcash, J Scott, Tiffany, Courtney A, Scangarella-Oman, Nicole E, Perry, Caroline R, Tao, Yu, Hossain, Mohammad, Barth, Aline, Dumont, Etienne F
Published in Antimicrobial agents and chemotherapy (23.06.2020)
Published in Antimicrobial agents and chemotherapy (23.06.2020)
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Lactate Limits T Cell Proliferation via the NAD(H) Redox State
Quinn, William J., Jiao, Jing, TeSlaa, Tara, Stadanlick, Jason, Wang, Zhonglin, Wang, Liqing, Akimova, Tatiana, Angelin, Alessia, Schäfer, Patrick M., Cully, Michelle D., Perry, Caroline, Kopinski, Piotr K., Guo, Lili, Blair, Ian A., Ghanem, Louis R., Leibowitz, Michael S., Hancock, Wayne W., Moon, Edmund K., Levine, Matthew H., Eruslanov, Evgeniy B., Wallace, Douglas C., Baur, Joseph A., Beier, Ulf H.
Published in Cell reports (Cambridge) (15.12.2020)
Published in Cell reports (Cambridge) (15.12.2020)
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Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria gonorrhoeae
Scangarella-Oman, Nicole E, Hossain, Mohammad, Dixon, Paula B, Ingraham, Karen, Min, Sharon, Tiffany, Courtney A, Perry, Caroline R, Raychaudhuri, Aparna, Dumont, Etienne F, Huang, Jianzhong, Hook, 3rd, Edward W, Miller, Linda A
Published in Antimicrobial agents and chemotherapy (01.12.2018)
Published in Antimicrobial agents and chemotherapy (01.12.2018)
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Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth
Miller, Katelyn D, Pniewski, Katherine, Perry, Caroline E, Papp, Sara B, Shaffer, Joshua D, Velasco-Silva, Jesse N, Casciano, Jessica C, Aramburu, Tomas M, Srikanth, Yellamelli V V, Cassel, Joel, Skordalakes, Emmanuel, Kossenkov, Andrew V, Salvino, Joseph M, Schug, Zachary T
Published in Cancer research (Chicago, Ill.) (01.03.2021)
Published in Cancer research (Chicago, Ill.) (01.03.2021)
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Pharmacokinetics of Oral Formulations of Gepotidacin (GSK2140944), a Triazaacenaphthylene Bacterial Type II Topoisomerase Inhibitor, in Healthy Adult and Adolescent Participants
Barth, Aline, Hossain, Mohammad, Brimhall, Darin B, Perry, Caroline R, Tiffany, Courtney A, Xu, Sherry, Dumont, Etienne F
Published in Antimicrobial agents and chemotherapy (18.01.2022)
Published in Antimicrobial agents and chemotherapy (18.01.2022)
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Dose selection for a phase III study evaluating gepotidacin (GSK2140944) in the treatment of uncomplicated urogenital gonorrhoea
Scangarella-Oman, Nicole E, Hossain, Mohammad, Perry, Caroline R, Tiffany, Courtney, Powell, Marcy, Swift, Brandon, Dumont, Etienne F
Published in Sexually transmitted infections (01.02.2023)
Published in Sexually transmitted infections (01.02.2023)
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