Using human genetics to understand the disease impacts of testosterone in men and women
Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.
Published in Nature medicine (01.02.2020)
Published in Nature medicine (01.02.2020)
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Journal Article
Partitioning heritability by functional annotation using genome-wide association summary statistics
Finucane, Hilary K, Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R, Purcell, Shaun, Stahl, Eli, Lindstrom, Sara, Perry, John R B, Okada, Yukinori, Raychaudhuri, Soumya, Daly, Mark J, Patterson, Nick, Neale, Benjamin M, Price, Alkes L
Published in Nature genetics (01.11.2015)
Published in Nature genetics (01.11.2015)
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Journal Article
Causal associations between cardiorespiratory fitness and type 2 diabetes
Cai, Lina, Gonzales, Tomas, Wheeler, Eleanor, Kerrison, Nicola D., Day, Felix R., Langenberg, Claudia, Perry, John R. B., Brage, Soren, Wareham, Nicholas J.
Published in Nature communications (03.07.2023)
Published in Nature communications (03.07.2023)
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Journal Article
Identifying genetic variants that affect viability in large cohorts
Mostafavi, Hakhamanesh, Berisa, Tomaz, Day, Felix R, Perry, John R B, Przeworski, Molly, Pickrell, Joseph K
Published in PLoS biology (05.09.2017)
Published in PLoS biology (05.09.2017)
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Journal Article
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A E, Lee, Sang Hong, Robinson, Matthew R, Perry, John R B, Nolte, Ilja M, van Vliet-Ostaptchouk, Jana V, Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K E, Pedersen, Nancy L, Ingelsson, Erik, Soranzo, Nicole, Keller, Matthew C, Wray, Naomi R, Goddard, Michael E, Visscher, Peter M
Published in Nature genetics (01.10.2015)
Published in Nature genetics (01.10.2015)
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Journal Article
Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause
Yazdanpanah, Mojgan, Yazdanpanah, Nahid, Gamache, Isabel, Ong, Ken, Perry, John R B, Manousaki, Despoina
Published in Genome medicine (28.05.2024)
Published in Genome medicine (28.05.2024)
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Journal Article
QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
Maharaj, Avinaash V., Ishida, Miho, Rybak, Anna, Elfeky, Reem, Andrews, Afiya, Joshi, Aakash, Elmslie, Frances, Joensuu, Anni, Kantojärvi, Katri, Jia, Raina Y., Perry, John R. B., O’Toole, Edel A., McGuffin, Liam J., Hwa, Vivian, Storr, Helen L.
Published in Nature communications (28.09.2024)
Published in Nature communications (28.09.2024)
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Journal Article
GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health
Zhao, Yajie, Stankovic, Stasa, Koprulu, Mine, Wheeler, Eleanor, Day, Felix R., Lango Allen, Hana, Kerrison, Nicola D., Pietzner, Maik, Loh, Po-Ru, Wareham, Nicholas J., Langenberg, Claudia, Ong, Ken K., Perry, John R. B.
Published in Nature communications (07.07.2021)
Published in Nature communications (07.07.2021)
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Journal Article
Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation
Radford, Elizabeth J., Tan, Hong-Kee, Andersson, Malin H. L., Stephenson, James D., Gardner, Eugene J., Ironfield, Holly, Waters, Andrew J., Gitterman, Daniel, Lindsay, Sarah, Abascal, Federico, Martincorena, Iñigo, Kolesnik-Taylor, Anna, Ng-Cordell, Elise, Firth, Helen V., Baker, Kate, Perry, John R. B., Adams, David J., Gerety, Sebastian S., Hurles, Matthew E.
Published in Nature communications (06.12.2023)
Published in Nature communications (06.12.2023)
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Elucidating the genetic architecture of reproductive ageing in the Japanese population
Horikoshi, Momoko, Day, Felix R., Akiyama, Masato, Hirata, Makoto, Kamatani, Yoichiro, Matsuda, Koichi, Ishigaki, Kazuyoshi, Kanai, Masahiro, Wright, Hollis, Toro, Carlos A., Ojeda, Sergio R., Lomniczi, Alejandro, Kubo, Michiaki, Ong, Ken K., Perry, John. R. B.
Published in Nature communications (17.05.2018)
Published in Nature communications (17.05.2018)
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Journal Article
Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work
Anderson, Greg M, Hill, Jennifer W, Kaiser, Ursula B, Navarro, Victor M, Ong, Ken K, Perry, John R B, Prevot, Vincent, Tena-Sempere, Manuel, Elias, Carol F
Published in Nature reviews. Endocrinology (01.02.2024)
Published in Nature reviews. Endocrinology (01.02.2024)
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Journal Article
A genome-wide association study identifies protein quantitative trait loci (pQTLs)
Melzer, David, Perry, John R B, Hernandez, Dena, Corsi, Anna-Maria, Stevens, Kara, Rafferty, Ian, Lauretani, Fulvio, Murray, Anna, Gibbs, J Raphael, Paolisso, Giuseppe, Rafiq, Sajjad, Simon-Sanchez, Javier, Lango, Hana, Scholz, Sonja, Weedon, Michael N, Arepalli, Sampath, Rice, Neil, Washecka, Nicole, Hurst, Alison, Britton, Angela, Henley, William, van de Leemput, Joyce, Li, Rongling, Newman, Anne B, Tranah, Greg, Harris, Tamara, Panicker, Vijay, Dayan, Colin, Bennett, Amanda, McCarthy, Mark I, Ruokonen, Aimo, Jarvelin, Marjo-Riitta, Guralnik, Jack, Bandinelli, Stefania, Frayling, Timothy M, Singleton, Andrew, Ferrucci, Luigi
Published in PLoS genetics (01.05.2008)
Published in PLoS genetics (01.05.2008)
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Journal Article
Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
MENNI, Cristina, FAUMAN, Eric, WEI YUAN, MILBURN, Mike, PALMER, Colin N. A, FRAYLING, Timothy M, TRIMMER, Jeff, BELL, Jordana T, GIEGER, Christian, MOHNEY, Rob P, BROSNAN, Mary Julia, SUHRE, Karsten, ERTE, Idil, SORANZO, Nicole, SPECTOR, Tim D, PERRY, John R. B, KASTENMÜLLER, Gabi, SHIN, So-Youn, PETERSEN, Ann-Kristin, HYDE, Craig, PSATHA, Maria, WARD, Kirsten J
Published in Diabetes (New York, N.Y.) (01.12.2013)
Published in Diabetes (New York, N.Y.) (01.12.2013)
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Journal Article
Shared and distinct genetic etiologies for different types of clonal hematopoiesis
Brown, Derek W., Cato, Liam D., Zhao, Yajie, Nandakumar, Satish K., Bao, Erik L., Gardner, Eugene J., Hubbard, Aubrey K., DePaulis, Alexander, Rehling, Thomas, Song, Lei, Yu, Kai, Chanock, Stephen J., Perry, John R. B., Sankaran, Vijay G., Machiela, Mitchell J.
Published in Nature communications (08.09.2023)
Published in Nature communications (08.09.2023)
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Journal Article
Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food
Dearden, Laura, Furigo, Isadora C, Pantaleão, Lucas C, Wong, L W P, Fernandez-Twinn, Denise S, de Almeida-Faria, Juliana, Kentistou, Katherine A, Carreira, Maria V, Bidault, Guillaume, Vidal-Puig, Antonio, Ong, Ken K, Perry, John R B, Donato, Jr, Jose, Ozanne, Susan E
Published in PLoS biology (04.06.2024)
Published in PLoS biology (04.06.2024)
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Journal Article
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Finucane, Hilary K., Reshef, Yakir A., Anttila, Verneri, Slowikowski, Kamil, Gusev, Alexander, Byrnes, Andrea, Gazal, Steven, Loh, Po-Ru, Lareau, Caleb, Shoresh, Noam, Genovese, Giulio, Saunders, Arpiar, Macosko, Evan, Pollack, Samuela, Perry, John R. B., Buenrostro, Jason D., Bernstein, Bradley E., Raychaudhuri, Soumya, McCarroll, Steven, Neale, Benjamin M., Price, Alkes L.
Published in Nature genetics (01.04.2018)
Published in Nature genetics (01.04.2018)
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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation
Wood, Andrew R, Perry, John R B, Tanaka, Toshiko, Hernandez, Dena G, Zheng, Hou-Feng, Melzer, David, Gibbs, J Raphael, Nalls, Michael A, Weedon, Michael N, Spector, Tim D, Richards, J Brent, Bandinelli, Stefania, Ferrucci, Luigi, Singleton, Andrew B, Frayling, Timothy M
Published in PloS one (16.05.2013)
Published in PloS one (16.05.2013)
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Prepubertal Dietary and Plasma Phospholipid Fatty Acids Related to Puberty Timing: Longitudinal Cohort and Mendelian Randomization Analyses
Cheng, Tuck Seng, Day, Felix R, Perry, John R B, Luan, Jian'an, Langenberg, Claudia, Forouhi, Nita G, Wareham, Nicholas J, Ong, Ken K
Published in Nutrients (30.05.2021)
Published in Nutrients (30.05.2021)
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Journal Article
Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes
Yuan, Xin, Waterworth, Dawn, Perry, John R.B., Lim, Noha, Song, Kijoung, Chambers, John C., Zhang, Weihua, Vollenweider, Peter, Stirnadel, Heide, Johnson, Toby, Bergmann, Sven, Beckmann, Noam D., Li, Yun, Ferrucci, Luigi, Melzer, David, Hernandez, Dena, Singleton, Andrew, Scott, James, Elliott, Paul, Waeber, Gerard, Cardon, Lon, Frayling, Timothy M., Kooner, Jaspal S., Mooser, Vincent
Published in American journal of human genetics (01.10.2008)
Published in American journal of human genetics (01.10.2008)
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