Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Cohen, Jonathan C, Hobbs, Helen H, Romeo, Stefano, Kozlitina, Julia, Xing, Chao, Pertsemlidis, Alexander, Cox, David, Pennacchio, Len A, Boerwinkle, Eric
Published in Nature genetics (01.12.2008)
Published in Nature genetics (01.12.2008)
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Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation
Preissl, Sebastian, Fang, Rongxin, Huang, Hui, Zhao, Yuan, Raviram, Ramya, Gorkin, David U., Zhang, Yanxiao, Sos, Brandon C., Afzal, Veena, Dickel, Diane E., Kuan, Samantha, Visel, Axel, Pennacchio, Len A., Zhang, Kun, Ren, Bing
Published in Nature neuroscience (01.03.2018)
Published in Nature neuroscience (01.03.2018)
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Genomic Patterns of De Novo Mutation in Simplex Autism
Turner, Tychele N., Coe, Bradley P., Dickel, Diane E., Hoekzema, Kendra, Nelson, Bradley J., Zody, Michael C., Kronenberg, Zev N., Hormozdiari, Fereydoun, Raja, Archana, Pennacchio, Len A., Darnell, Robert B., Eichler, Evan E.
Published in Cell (19.10.2017)
Published in Cell (19.10.2017)
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ChIP-seq accurately predicts tissue-specific activity of enhancers
Visel, Axel, Blow, Matthew J., Li, Zirong, Zhang, Tao, Akiyama, Jennifer A., Holt, Amy, Plajzer-Frick, Ingrid, Shoukry, Malak, Wright, Crystal, Chen, Feng, Afzal, Veena, Ren, Bing, Rubin, Edward M., Pennacchio, Len A.
Published in Nature (12.02.2009)
Published in Nature (12.02.2009)
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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
Romeo, Stefano, Yin, Wu, Kozlitina, Julia, Pennacchio, Len A, Boerwinkle, Eric, Hobbs, Helen H, Cohen, Jonathan C
Published in The Journal of clinical investigation (01.01.2009)
Published in The Journal of clinical investigation (01.01.2009)
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The changing mouse embryo transcriptome at whole tissue and single-cell resolution
He, Peng, Williams, Brian A., Trout, Diane, Marinov, Georgi K., Amrhein, Henry, Berghella, Libera, Goh, Say-Tar, Plajzer-Frick, Ingrid, Afzal, Veena, Pennacchio, Len A., Dickel, Diane E., Visel, Axel, Ren, Bing, Hardison, Ross C., Zhang, Yu, Wold, Barbara J.
Published in Nature (London) (30.07.2020)
Published in Nature (London) (30.07.2020)
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Dlx1&2-Dependent Expression of Zfhx1b (Sip1, Zeb2) Regulates the Fate Switch between Cortical and Striatal Interneurons
McKinsey, Gabriel L., Lindtner, Susan, Trzcinski, Brett, Visel, Axel, Pennacchio, Len A., Huylebroeck, Danny, Higashi, Yujiro, Rubenstein, John L.R.
Published in Neuron (Cambridge, Mass.) (09.01.2013)
Published in Neuron (Cambridge, Mass.) (09.01.2013)
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Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
Cohen, Jonathan C, May, Dalit, Afzal, Veena, Gong, Elaine, Pennacchio, Len A, Zhu, Yiwen, Rubin, Edward M, Attanasio, Catia, Blow, Matthew J, Visel, Axel
Published in Nature (London) (18.03.2010)
Published in Nature (London) (18.03.2010)
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Progressive Loss of Function in a Limb Enhancer during Snake Evolution
Kvon, Evgeny Z., Kamneva, Olga K., Melo, Uirá S., Barozzi, Iros, Osterwalder, Marco, Mannion, Brandon J., Tissières, Virginie, Pickle, Catherine S., Plajzer-Frick, Ingrid, Lee, Elizabeth A., Kato, Momoe, Garvin, Tyler H., Akiyama, Jennifer A., Afzal, Veena, Lopez-Rios, Javier, Rubin, Edward M., Dickel, Diane E., Pennacchio, Len A., Visel, Axel
Published in Cell (20.10.2016)
Published in Cell (20.10.2016)
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The Epigenomic Landscape of Prokaryotes
Blow, Matthew J, Clark, Tyson A, Daum, Chris G, Deutschbauer, Adam M, Fomenkov, Alexey, Fries, Roxanne, Froula, Jeff, Kang, Dongwan D, Malmstrom, Rex R, Morgan, Richard D, Posfai, Janos, Singh, Kanwar, Visel, Axel, Wetmore, Kelly, Zhao, Zhiying, Rubin, Edward M, Korlach, Jonas, Pennacchio, Len A, Roberts, Richard J
Published in PLoS genetics (12.02.2016)
Published in PLoS genetics (12.02.2016)
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Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease
Chatterjee, Sumantra, Kapoor, Ashish, Akiyama, Jennifer A., Auer, Dallas R., Lee, Dongwon, Gabriel, Stacey, Berrios, Courtney, Pennacchio, Len A., Chakravarti, Aravinda
Published in Cell (06.10.2016)
Published in Cell (06.10.2016)
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Germline Chd8 haploinsufficiency alters brain development in mouse
Gompers, Andrea L, Su-Feher, Linda, Ellegood, Jacob, Copping, Nycole A, Riyadh, M Asrafuzzaman, Stradleigh, Tyler W, Pride, Michael C, Schaffler, Melanie D, Wade, A Ayanna, Catta-Preta, Rinaldo, Zdilar, Iva, Louis, Shreya, Kaushik, Gaurav, Mannion, Brandon J, Plajzer-Frick, Ingrid, Afzal, Veena, Visel, Axel, Pennacchio, Len A, Dickel, Diane E, Lerch, Jason P, Crawley, Jacqueline N, Zarbalis, Konstantinos S, Silverman, Jill L, Nord, Alex S
Published in Nature neuroscience (01.08.2017)
Published in Nature neuroscience (01.08.2017)
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Ultraconserved Enhancers Are Required for Normal Development
Dickel, Diane E., Ypsilanti, Athena R., Pla, Ramón, Zhu, Yiwen, Barozzi, Iros, Mannion, Brandon J., Khin, Yupar S., Fukuda-Yuzawa, Yoko, Plajzer-Frick, Ingrid, Pickle, Catherine S., Lee, Elizabeth A., Harrington, Anne N., Pham, Quan T., Garvin, Tyler H., Kato, Momoe, Osterwalder, Marco, Akiyama, Jennifer A., Afzal, Veena, Rubenstein, John L.R., Pennacchio, Len A., Visel, Axel
Published in Cell (25.01.2018)
Published in Cell (25.01.2018)
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Tissue-specific RNA expression marks distant-acting developmental enhancers
Wu, Han, Nord, Alex S, Akiyama, Jennifer A, Shoukry, Malak, Afzal, Veena, Rubin, Edward M, Pennacchio, Len A, Visel, Axel
Published in PLoS genetics (01.09.2014)
Published in PLoS genetics (01.09.2014)
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Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen
Hess, Matthias, Sczyrba, Alexander, Egan, Rob, Kim, Tae-Wan, Chokhawala, Harshal, Schroth, Gary, Luo, Shujun, Clark, Douglas S., Chen, Feng, Zhang, Tao, Mackie, Roderick I., Pennacchio, Len A., Tringe, Susannah G., Visel, Axel, Woyke, Tanja, Wang, Zhong, Rubin, Edward M.
Published in Science (American Association for the Advancement of Science) (28.01.2011)
Published in Science (American Association for the Advancement of Science) (28.01.2011)
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Massively parallel functional dissection of mammalian enhancers in vivo
Patwardhan, Rupali P, Hiatt, Joseph B, Witten, Daniela M, Kim, Mee J, Smith, Robin P, May, Dalit, Lee, Choli, Andrie, Jennifer M, Lee, Su-In, Cooper, Gregory M, Ahituv, Nadav, Pennacchio, Len A, Shendure, Jay
Published in Nature biotechnology (01.03.2012)
Published in Nature biotechnology (01.03.2012)
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Transcriptional Regulation of Enhancers Active in Protodomains of the Developing Cerebral Cortex
Pattabiraman, Kartik, Golonzhka, Olga, Lindtner, Susan, Nord, Alex S., Taher, Leila, Hoch, Renee, Silberberg, Shanni N., Zhang, Dongji, Chen, Bin, Zeng, HongKui, Pennacchio, Len A., Puelles, Luis, Visel, Axel, Rubenstein, John L.R.
Published in Neuron (Cambridge, Mass.) (04.06.2014)
Published in Neuron (Cambridge, Mass.) (04.06.2014)
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Spatiotemporal DNA methylome dynamics of the developing mouse fetus
He, Yupeng, Hariharan, Manoj, Gorkin, David U., Dickel, Diane E., Luo, Chongyuan, Castanon, Rosa G., Nery, Joseph R., Lee, Ah Young, Zhao, Yuan, Huang, Hui, Williams, Brian A., Trout, Diane, Amrhein, Henry, Fang, Rongxin, Chen, Huaming, Li, Bin, Visel, Axel, Pennacchio, Len A., Ren, Bing, Ecker, Joseph R.
Published in Nature (London) (30.07.2020)
Published in Nature (London) (30.07.2020)
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Journal Article
Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease
He, Aibin, Gu, Fei, Hu, Yong, Ma, Qing, Yi Ye, Lillian, Akiyama, Jennifer A., Visel, Axel, Pennacchio, Len A., Pu, William T.
Published in Nature communications (24.09.2014)
Published in Nature communications (24.09.2014)
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