Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
Leibowitz, Mitchell L., Papathanasiou, Stamatis, Doerfler, Phillip A., Blaine, Logan J., Sun, Lili, Yao, Yu, Zhang, Cheng-Zhong, Weiss, Mitchell J., Pellman, David
Published in Nature genetics (01.06.2021)
Published in Nature genetics (01.06.2021)
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Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds
Kwon, Mijung, Bagonis, Maria, Danuser, Gaudenz, Pellman, David
Published in Developmental cell (10.08.2015)
Published in Developmental cell (10.08.2015)
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Chromothripsis from DNA damage in micronuclei
Zhang, Cheng-Zhong, Spektor, Alexander, Cornils, Hauke, Francis, Joshua M., Jackson, Emily K., Liu, Shiwei, Meyerson, Matthew, Pellman, David
Published in Nature (London) (11.06.2015)
Published in Nature (London) (11.06.2015)
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Mechanisms generating cancer genome complexity from a single cell division error
Umbreit, Neil T, Zhang, Cheng-Zhong, Lynch, Luke D, Blaine, Logan J, Cheng, Anna M, Tourdot, Richard, Sun, Lili, Almubarak, Hannah F, Judge, Kim, Mitchell, Thomas J, Spektor, Alexander, Pellman, David
Published in Science (American Association for the Advancement of Science) (17.04.2020)
Published in Science (American Association for the Advancement of Science) (17.04.2020)
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The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome
Wu, R. Alex, Pellman, David S., Walter, Johannes C.
Published in Trends in cell biology (01.02.2021)
Published in Trends in cell biology (01.02.2021)
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Chromothripsis: A New Mechanism for Rapid Karyotype Evolution
Leibowitz, Mitchell L, Zhang, Cheng-Zhong, Pellman, David
Published in Annual review of genetics (23.11.2015)
Published in Annual review of genetics (23.11.2015)
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Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
Zhang, Cheng-Zhong, Leibowitz, Mitchell L, Pellman, David
Published in Genes & development (01.12.2013)
Published in Genes & development (01.12.2013)
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DNA breaks and chromosome pulverization from errors in mitosis
Crasta, Karen, Ganem, Neil J., Dagher, Regina, Lantermann, Alexandra B., Ivanova, Elena V., Pan, Yunfeng, Nezi, Luigi, Protopopov, Alexei, Chowdhury, Dipanjan, Pellman, David
Published in Nature (London) (02.02.2012)
Published in Nature (London) (02.02.2012)
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Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
Papathanasiou, Stamatis, Markoulaki, Styliani, Blaine, Logan J., Leibowitz, Mitchell L., Zhang, Cheng-Zhong, Jaenisch, Rudolf, Pellman, David
Published in Nature communications (06.10.2021)
Published in Nature communications (06.10.2021)
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Oncogene-like induction of cellular invasion from centrosome amplification
Godinho, Susana A., Picone, Remigio, Burute, Mithila, Dagher, Regina, Su, Ying, Leung, Cheuk T., Polyak, Kornelia, Brugge, Joan S., Théry, Manuel, Pellman, David
Published in Nature (London) (05.06.2014)
Published in Nature (London) (05.06.2014)
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Polyploidy can drive rapid adaptation in yeast
Selmecki, Anna M., Maruvka, Yosef E., Richmond, Phillip A., Guillet, Marie, Shoresh, Noam, Sorenson, Amber L., De, Subhajyoti, Kishony, Roy, Michor, Franziska, Dowell, Robin, Pellman, David
Published in Nature (London) (19.03.2015)
Published in Nature (London) (19.03.2015)
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Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements
Deng, Lin, Wu, R. Alex, Sonneville, Remi, Kochenova, Olga V., Labib, Karim, Pellman, David, Walter, Johannes C.
Published in Molecular cell (07.03.2019)
Published in Molecular cell (07.03.2019)
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Absolute quantification of somatic DNA alterations in human cancer
Carter, Scott L, Cibulskis, Kristian, Helman, Elena, McKenna, Aaron, Shen, Hui, Zack, Travis, Laird, Peter W, Onofrio, Robert C, Winckler, Wendy, Weir, Barbara A, Beroukhim, Rameen, Pellman, David, Levine, Douglas A, Lander, Eric S, Meyerson, Matthew, Getz, Gad
Published in Nature biotechnology (01.05.2012)
Published in Nature biotechnology (01.05.2012)
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Proteasomal Degradation Resolves Competition between Cell Polarization and Cellular Wound Healing
Kono, Keiko, Saeki, Yasushi, Yoshida, Satoshi, Tanaka, Keiji, Pellman, David
Published in Cell (06.07.2012)
Published in Cell (06.07.2012)
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Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
Oser, Matthew G, Fonseca, Raquel, Chakraborty, Abhishek A, Brough, Rachel, Spektor, Alexander, Jennings, Rebecca B, Flaifel, Abdallah, Novak, Jesse S, Gulati, Aditi, Buss, Elizabeth, Younger, Scott T, McBrayer, Samuel K, Cowley, Glenn S, Bonal, Dennis M, Nguyen, Quang-De, Brulle-Soumare, Laura, Taylor, Paula, Cairo, Stefano, Ryan, Colm J, Pease, Elizabeth J, Maratea, Kim, Travers, Jon, Root, David E, Signoretti, Sabina, Pellman, David, Ashton, Susan, Lord, Christopher J, Barry, Simon T, Kaelin, Jr, William G
Published in Cancer discovery (01.02.2019)
Published in Cancer discovery (01.02.2019)
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