PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, GREY, Jr., Ronald Lee, HURLEY, Dennis James, BOUCHER, Diane Marie, FIMOGNARI, Jr., Robert Francis, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JOHNSON, Jr., Mac Arthur, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, NUHANT, Philippe Marcel
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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MODULATORS OF ALPHA-1 ANTITRYPSIN
GAGNON, Kevin James, COTTRELL, Kevin Michael, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, FANNING, Lev Tyler Dewey, JOHNSON, JR., Mac Arthur, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, GREY, JR., Ronald Lee, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, Jones, Peter, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 10.10.2024
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Year of Publication 10.10.2024
Patent
Modulators of alpha-1 antitrypsin
Gagnon, Kevin James, Overhoff, Kirk Alan, Damagnez, Veronique, Hood, Sarah Carol, Johnson, Jr., Mac Arthur, Ronkin, Steven M, Garcia Barrantes, Pedro Manuel, Bligh, Cavan McKeon, Fleming, Gabrielle Simone, Giroux, Simon, Thomson, Stephen, Giacometti, Robert Daniel, Grey, Jr., Ronald Lee, Liu, Siying, Sposato, Marisa, Zaky, Mariam, Cottrell, Kevin Michael, Tang, Qing, Lai, Mei-Hsiu, Sawant, Rupa, Fanning, Lev Tyler Dewey, Kesavan, Sarathy, Stavropoulos, Kathy, Medek, Ales, Maxwell, Brad, Shi, Yi, Brodney, Michael Aaron, Maxwell, John Patrick, Nuhant, Philippe Marcel, Tapley, Timothy Lewis, Hurley, Dennis James, Boyd, Michael John, Hall, Amy Beth, Roday, Setu, Fimognari, Robert Francis, Xu, Jinwang, Clark, Michael Philip, Looker, Adam, Boucher, Diane, Guido, Samantha, Jones, Peter, Bandarage, Upul Keerthi, Shrestha, Muna, Swett, Rebecca Jane, Roeper, Stefanie
Year of Publication 30.01.2024
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Year of Publication 30.01.2024
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1H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
ZHANG, Hu, HALL, Amy B, COTTRELL, Kevin Michael, GARCIA BARRANTES, Pedro Manuel, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KARNS, Alexander S, BANDARAGE, Upul Keerthi, JOHNSON, Jr., Mac Arthur, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, ALLEN, Emily Elizabeth, NUHANT, Philippe Marcel, LIAO, Yusheng, TANG, Qing
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
Patent
Pyrrolo(2,3-f)indazole and 2,4,5,10-tetrazatricyclo(7.3.0.03,7)dodeca-1,3(7),5,8,11-pentaene derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, GREY Jr., Ronald Lee, HURLEY, Dennis James, BOUCHER, Diane Marie, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, JOHNSON, Jr, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, FANNING, Lev T. D, NUHANT, Philippe Marcel, FIMOGNARI Jr., Robert Francis
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
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PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, HURLEY, Dennis James, BOUCHER, Diane Marie, MAXWELL, John Patrick, FIMOGNARI, JR., Robert Francis, XU, Jinwang, JOHNSON, JR., Mac Arthur, DAMAGNEZ, Veronique, KESAVAN, Sarathy, GREY, JR., Ronald Lee, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, FANNING, Lev T., D, SWETT, Rebecca Jane, GIROUX, Simon, NUHANT, Philippe Marcel
Year of Publication 08.02.2023
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Year of Publication 08.02.2023
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1 H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1 H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)
ZHANG, Hu, HALL, Amy B, COTTRELL, Kevin Michael, GARCIA BARRANTES, Pedro Manuel, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, JOHNSON, JR., Mac Arthur, DAMAGNEZ, Veronique, KARNS, Alexander S, BANDARAGE, Upul Keerthi, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, ALLEN, Emily Elizabeth, NUHANT, Philippe Marcel, LIAO, Yusheng, TANG, Qing
Year of Publication 08.02.2023
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Year of Publication 08.02.2023
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1 H-pyrazolo(4,3-g)isoquinoline and 1 H-pyrazolo(4,3-g)quinoline derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (AATD)
ZHANG, Hu, HALL, Amy B, COTTRELL, Kevin Michael, GARCIA BARRANTES, Pedro Manuel, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KARNS, Alexander S, BANDARAGE, Upul Keerthi, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, JOHNSON Jr., Mac Arthur, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, ALLEN, Emily Elizabeth, NUHANT, Philippe Marcel, LIAO, Yusheng, TANG, Qing
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
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PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, JOHNSON, JR, HURLEY, Dennis James, BOUCHER, Diane Marie, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, FIMOGNARI, JR, GREY, JR, THOMSON, Stephen A, FANNING, Lev T, SWETT, Rebecca Jane, GIROUX, Simon, NUHANT, Philippe Marcel
Year of Publication 07.10.2021
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Year of Publication 07.10.2021
Patent
MODULATORS OF ALPHA-1 ANTITRYPSIN
JONES, PETER, MAXWELL, JOHN PATRICK, GARCIA BARRANTES, PEDRO MANUEL, HALL, AMY B, GIROUX, SIMON, XU, JINWANG, FANNING, LEV T. D, HURLEY, DENNIS JAMES, JOHNSON, JR, COTTRELL, KEVIN MICHAEL, TAPLEY, TIMOTHY LEWIS, ZAKY, MARIAM, SWETT, REBECCA JANE, THOMSON, STEPHEN A, DAMAGNEZ, VERONIQUE, BOYD, MICHAEL JOHN, FIMOGNARI, JR, GREY, JR, KESAVAN, SARATHY, NUHANT, PHILIPPE MARCEL, BRODNEY, MICHAEL AARON, BOUCHER, DIANE MARIE
Year of Publication 07.10.2021
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Year of Publication 07.10.2021
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MODULATORS OF ALPHA-1 ANTITRYPSIN
KARNS, ALEXANDER S, GALE-DAY, ZACHARY, MAXWELL, JOHN PATRICK, GARCIA BARRANTES, PEDRO MANUEL, HALL, AMY B, JOHNSON, MAC ARTHUR, BANDARAGE, UPUL KEERTHI, GIROUX, SIMON, XU, JINWANG, HURLEY, DENNIS JAMES, COTTRELL, KEVIN MICHAEL, TAPLEY, TIMOTHY LEWIS, SWETT, REBECCA JANE, TANG, QING, GU, WENXIN, ALLEN, EMILY ELIZABETH, FANNING, LEV T.D, THOMSON, STEPHEN A, LIAO, YUSHENG, ZHANG, HU, DAMAGNEZ, VERONIQUE, DENINNO, MICHAEL PAUL, NUHANT, PHILIPPE MARCEL, BOUCHER, DIANE MARIE
Year of Publication 07.10.2021
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Year of Publication 07.10.2021
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1 H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1 H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)
ZHANG, Hu, HALL, Amy B, COTTRELL, Kevin Michael, GARCIA BARRANTES, Pedro Manuel, JOHNSON, JR, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KARNS, Alexander S, BANDARAGE, Upul Keerthi, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, ALLEN, Emily Elizabeth, NUHANT, Philippe Marcel, LIAO, Yusheng, TANG, Qing
Year of Publication 07.10.2021
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Year of Publication 07.10.2021
Patent
CONDENSED TRICYCLIC PYRROLES AS ALPHA-1 ANTITRYPSIN MODULATORS
GAGNON, Kevin James, COTTRELL, Kevin Michael, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, FANNING, Lev Tyler Dewey, JOHNSON, JR., Mac Arthur, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, JONES, Peter, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, GREY JR., Ronald Lee, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 23.03.2022
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Year of Publication 23.03.2022
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PYRROLES TRICYCLIQUES CONDENSÉS UTILISÉS COMME MODULATEURS DE L'ALPHA-1 ANTITRYPSINE
COTTRELL, Kevin Michael, GAGNON, Kevin James, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, FANNING, Lev Tyler Dewey, JOHNSON, JR., Mac Arthur, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, JONES, Peter, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, GREY JR., Ronald Lee, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 23.03.2022
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Year of Publication 23.03.2022
Patent
Condensed tryciclic pyrroles as alpha-1 antitrypsin modulators
GAGNON, Kevin James, COTTRELL, Kevin Michael, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, GREY Jr., Ronald Lee, RODAY, Setu, GIACOMETTI, Robert Daniel, FANNING, Lev Tyler Dewey, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, JONES, Peter, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, JOHNSON Jr., Mac Arthur, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
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CONDENSED TRICYCLIC PYRROLES AS ALPHA-1 ANTITRYPSIN MODULATORS
GAGNON, Kevin James, COTTRELL, Kevin Michael, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, JOHNSON, JR, FANNING, Lev Tyler Dewey, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, JONES, Peter, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, GREY JR., Ronald Lee, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 30.12.2021
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Year of Publication 30.12.2021
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CONDENSED TRYCICLIC PYRROLES AS ALPHA-1 ANTITRYPSIN MODULATORS
GAGNON, Kevin James, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, JOHNSON, JR, FANNING, Lev Tyler Dewey, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, JONES, Peter, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, GREY JR., Ronald Lee, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 10.12.2020
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Year of Publication 10.12.2020
Patent
MODULATORS OF ALPHA-1 ANTITRYPSIN
GAGNON, Kevin James, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, GREY, Jr., Ronald Lee, FANNING, Lev Tyler Dewey, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, JOHNSON, Jr., Mac Arthur, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, Jones, Peter, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 19.11.2020
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Year of Publication 19.11.2020
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CONDENSED TRYCICLIC PYRROLES AS ALPHA-1 ANTITRYPSIN MODULATORS
JONES, PETER, MAXWELL, JOHN PATRICK, LIU, SIYING, FANNING, LEV TYLER DEWEY, XU, JINWANG, HURLEY, DENNIS JAMES, JOHNSON, JR, LAI, MEI-HSIU, TAPLEY, TIMOTHY LEWIS, HOOD, SARAH CAROL, ZAKY, MARIAM, RODAY, SETU, SWETT, REBECCA JANE, GREY JR., RONALD LEE, SHI, YI, SHRESTHA, MUNA, DAMAGNEZ, VERONIQUE, GIACOMETTI, ROBERT DANIEL, BOYD, MICHAEL JOHN, GUIDO, SAMANTHA, SAWANT, RUPA, STAVROPOULOS, KATHY, MAXWELL, BRAD, CLARK, MICHAEL PHILIP, GARCIA BARRANTES, PEDRO MANUEL, BANDARAGE, UPUL KEERTHI, RONKIN, STEVEN M, GIROUX, SIMON, OVERHOFF, KIRK ALAN, SPOSATO, MARISA, COTTRELL, KEVIN MICHAEL, THOMSON, STEPHEN, BLIGH, CAVAN MCKEON, ROEPER, STEFANIE, TANG, QING, FIMOGNARI, ROBERT FRANCIS, GAGNON, KEVIN JAMES, BOUCHER, DIANE, LOOKER, ADAM, KESAVAN, SARATHY, FLEMING, GABRIELLE SIMONE, MEDEK, ALES, NUHANT, PHILIPPE MARCEL, BRODNEY, MICHAEL AARON, HALL, AMY BETH
Year of Publication 10.12.2020
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Year of Publication 10.12.2020
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