Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness
Acland, Gregory M, Aguirre, Gustavo D, Bennett, Jean, Aleman, Tomas S, Cideciyan, Artur V, Bennicelli, Jeannette, Dejneka, Nadine S, Pearce-Kelling, Susan E, Maguire, Albert M, Palczewski, Krzysztof, Hauswirth, William W, Jacobson, Samuel G
Published in Molecular therapy (01.12.2005)
Published in Molecular therapy (01.12.2005)
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Gene therapy restores vision in a canine model of childhood blindness
Bennett, Jean, Acland, Gregory M, Aguirre, Gustavo D, Ray, Jharna, Zhang, Qi, Aleman, Tomas S, Cideciyan, Artur V, Pearce-Kelling, Susan E, Anand, Vibha, Zeng, Yong, Maguire, Albert M, Jacobson, Samuel G, Hauswirth, William W
Published in Nature genetics (01.05.2001)
Published in Nature genetics (01.05.2001)
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In vivo Dynamics of Retinal Injury and Repair in the rhodopsin Mutant Dog Model of Human Retinitis Pigmentosa
Cideciyan, Artur V., Jacobson, Samuel G., Aleman, Tomas S., Gu, Danian, Pearce-Kelling, Susan E., Sumaroka, Alexander, Acland, Gregory M., Aguirre, Gustavo D., Nathans, Jeremy
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2005)
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COL9A2 and COL9A3 mutations in canine autosomal recessive oculoskeletal dysplasia
Goldstein, Orly, Guyon, Richard, Kukekova, Anna, Kuznetsova, Tatyana N, Pearce-Kelling, Susan E, Johnson, Jennifer, Aguirre, Gustavo D, Acland, Gregory M
Published in Mammalian genome (01.08.2010)
Published in Mammalian genome (01.08.2010)
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Canine RD3 mutation establishes rod-cone dysplasia type 2 (rcd2) as ortholog of human and murine rd3
Kukekova, Anna V, Goldstein, Orly, Johnson, Jennifer L, Richardson, Malcolm A, Pearce-Kelling, Susan E, Swaroop, Anand, Friedman, James S, Aguirre, Gustavo D, Acland, Gregory M
Published in Mammalian genome (01.02.2009)
Published in Mammalian genome (01.02.2009)
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Naturally Occurring rhodopsin Mutation in the Dog Causes Retinal Dysfunction and Degeneration Mimicking Human Dominant Retinitis Pigmentosa
Kijas, James W., Cideciyan, Artur V., Aleman, Tomas S., Pianta, Michael J., Pearce-Kelling, Susan E., Miller, Brian J., Jacobson, Samuel G., Aguirre, Gustavo D., Acland, Gregory M.
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2002)
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A Naturally Occurring Mutation of the Opsin Gene (T4R) in Dogs Affects Glycosylation and Stability of the G Protein-coupled Receptor
Zhu, Li, Jang, Geeng-Fu, Jastrzebska, Beata, Filipek, Slawomir, Pearce-Kelling, Susan E., Aguirre, Gustavo D., Stenkamp, Ronald E., Acland, Gregory M., Palczewski, Krzysztof
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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Genetic analysis of the modern Australian labradoodle dog breed reveals an excess of the poodle genome
Ali, Muhammad Basil, Evans, Jacquelyn M, Parker, Heidi G, Kim, Jaemin, Pearce-Kelling, Susan, Whitaker, D Thad, Plassais, Jocelyn, Khan, Qaiser M, Ostrander, Elaine A
Published in PLoS genetics (10.09.2020)
Published in PLoS genetics (10.09.2020)
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Global Frequency Analyses of Canine Progressive Rod-Cone Degeneration-Progressive Retinal Atrophy and Collie Eye Anomaly Using Commercial Genetic Testing Data
Clark, Jessica A, Anderson, Heidi, Donner, Jonas, Pearce-Kelling, Susan, Ekenstedt, Kari J
Published in Genes (01.11.2023)
Published in Genes (01.11.2023)
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Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection
Jacobson, Samuel G, Acland, Gregory M, Aguirre, Gustavo D, Aleman, Tomas S, Schwartz, Sharon B, Cideciyan, Artur V, Zeiss, Caroline J, Komaromy, Andras M, Kaushal, Shalesh, Roman, Alejandro J, Windsor, Elizabeth A M, Sumaroka, Alexander, Pearce-Kelling, Susan E, Conlon, Thomas J, Chiodo, Vincent A, Boye, Sanford L, Flotte, Terence R, Maguire, Albert M, Bennett, Jean, Hauswirth, William W
Published in Molecular therapy (01.06.2006)
Published in Molecular therapy (01.06.2006)
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Identical mutation in a novel retinal gene causes progressive rod–cone degeneration in dogs and retinitis pigmentosa in humans
Zangerl, Barbara, Goldstein, Orly, Philp, Alisdair R., Lindauer, Sarah J.P., Pearce-Kelling, Susan E., Mullins, Robert F., Graphodatsky, Alexander S., Ripoll, Daniel, Felix, Jeanette S., Stone, Edwin M., Acland, Gregory M., Aguirre, Gustavo D.
Published in Genomics (San Diego, Calif.) (01.11.2006)
Published in Genomics (San Diego, Calif.) (01.11.2006)
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Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis
Jacobson, Samuel G, Boye, Sanford L, Aleman, Tomas S, Conlon, Thomas J, Zeiss, Caroline J, Roman, Alejandro J, Cideciyan, Artur V, Schwartz, Sharon B, Komaromy, Andras M, Doobrajh, Michelle, Cheung, Andy Y, Sumaroka, Alexander, Pearce-Kelling, Susan E, Aguirre, Gustavo D, Kaushal, Shalesh, Maguire, Albert M, Flotte, Terence R, Hauswirth, William W
Published in Human gene therapy (01.08.2006)
Published in Human gene therapy (01.08.2006)
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Altered expression of retinal molecular markers in the canine RPE65 model of Leber congenital amaurosis
Hernández, Maria, Pearce-Kelling, Susan E, Rodriguez, F David, Aguirre, Gustavo D, Vecino, Elena
Published in Investigative ophthalmology & visual science (01.12.2010)
Published in Investigative ophthalmology & visual science (01.12.2010)
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An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9
Goldstein, Orly, Mezey, Jason G, Boyko, Adam R, Gao, Chuan, Wang, Wei, Bustamante, Carlos D, Anguish, Lynne J, Jordan, Julie Ann, Pearce-Kelling, Susan E, Aguirre, Gustavo D, Acland, Gregory M
Published in Molecular vision (11.08.2010)
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Published in Molecular vision (11.08.2010)
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Analysis of six candidate genes as potential modifiers of disease expression in canine XLPRA1, a model for human X-linked retinitis pigmentosa 3
Guyon, Richard, Pearce-Kelling, Susan E, Zeiss, Caroline J, Acland, Gregory M, Aguirre, Gustavo D
Published in Molecular vision (11.07.2007)
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Published in Molecular vision (11.07.2007)
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881. Safety, Efficacy and Biodistribution of Recombinant AAV2-RPE65 Vector Delivered by Ocular Subretinal Injection
Jacobson, Samuel G., Acland, Gregory M., Aguirre, Gustavo D., Aleman, Tomas S., Boye, Sanford L., Schwartz, Sharon B., Cideciyan, Artur V., Zeiss, Caroline J., Komaromy, Andras M., Roman, Alejandro J., Windsor, Elizabeth A.M., Sumaroka, Alexander, Pearce-Kelling, Susan E., Conlon, Thomas J., Li, Quihong, Chiodo, Vincent A., Flotte, Terence R., Maguire, Albert M., Bennett, Jean, Hauswirth, William W.
Published in Molecular therapy (01.05.2006)
Published in Molecular therapy (01.05.2006)
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Canine distemper epizootic in lions, tigers, and leopards in North America
Appel, M.J.G, Yates, R.A, Foley, G.L, Bernstein, J.J, Santinelli, S, Spelman, L.H, Miller, L.D, Arp, L.H, Anderson, M, Barr, M
Published in Journal of veterinary diagnostic investigation (01.07.1994)
Published in Journal of veterinary diagnostic investigation (01.07.1994)
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Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia
Yeh, Connie Y, Goldstein, Orly, Kukekova, Anna V, Holley, Debbie, Knollinger, Amy M, Huson, Heather J, Pearce-Kelling, Susan E, Acland, Gregory M, Komáromy, András M
Published in BMC genetics (20.04.2013)
Published in BMC genetics (20.04.2013)
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Molecular cloning, characterization and mapping of the canine glucocorticoid receptor DNA binding factor 1 (GRLF1)
Zangerl, Barbara, Zhang, Qi, Pearce-Kelling, Susan E, Aguirre, Gustavo D
Published in Gene (10.07.2002)
Published in Gene (10.07.2002)
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Genetic analysis of the modern Australian labradoodle dog breed reveals an excess of the poodle genome
Muhammad Basil Ali, Jacquelyn M Evans, Heidi G Parker, Jaemin Kim, Susan Pearce-Kelling, D Thad Whitaker, Jocelyn Plassais, Qaiser M Khan, Elaine A Ostrander
Published in PLoS genetics (01.09.2020)
Published in PLoS genetics (01.09.2020)
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