Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene
Doffe, Flora, Carbonnier, Vincent, Tissier, Manon, Leroy, Bernard, Martins, Isabelle, Mattsson, Johanna S. M., Micke, Patrick, Pavlova, Sarka, Pospisilova, Sarka, Smardova, Jana, Joerger, Andreas C., Wiman, Klas G., Kroemer, Guido, Soussi, Thierry
Published in Cell death and differentiation (01.05.2021)
Published in Cell death and differentiation (01.05.2021)
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Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia
Plešingerová, Hana, Janovská, Pavlína, Mishra, Archana, Smyčková, Lucie, Poppová, Lucie, Libra, Antonín, Plevová, Karla, Ovesná, Petra, Radová, Lenka, Doubek, Michael, Pavlová, Šárka, Pospíšilová, Šárka, Bryja, Vítězslav
Published in Haematologica (Roma) (01.02.2018)
Published in Haematologica (Roma) (01.02.2018)
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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing
Kurucova, Terezia, Reblova, Kamila, Janovska, Pavlina, Porc, Jakub Pawel, Navrkalova, Veronika, Pavlova, Sarka, Malcikova, Jitka, Plevova, Karla, Tichy, Boris, Doubek, Michael, Bryja, Vitezslav, Kotaskova, Jana, Pospisilova, Sarka
Published in Molecular oncology (01.10.2024)
Published in Molecular oncology (01.10.2024)
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Journal Article
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene
Poppova, Lucie, Pavlova, Sarka, Gonzalez, Beatriz, Kotaskova, Jana, Plevova, Karla, Dumbovic, Gabrijela, Janovska, Pavlina, Bystry, Vojtech, Panovska, Anna, Bezdekova, Lucie, Maslejova, Stanislava, Brychtova, Yvona, Doubek, Michael, Krzyzankova, Marcela, Borsky, Marek, Mayer, Jiri, Bryja, Vitezslav, Alonso, Sergio, Pospisilova, Sarka
Published in Epigenetics (01.12.2022)
Published in Epigenetics (01.12.2022)
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Journal Article
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Olbertova, Helena, Plevova, Karla, Pavlova, Sarka, Malcikova, Jitka, Kotaskova, Jana, Stranska, Kamila, Spunarova, Michaela, Trbusek, Martin, Navrkalova, Veronika, Dvorackova, Barbara, Tom, Nikola, Pal, Karol, Jarosova, Marie, Brychtova, Yvona, Panovska, Anna, Doubek, Michael, Pospisilova, Sarka
Published in BMC cancer (03.02.2022)
Published in BMC cancer (03.02.2022)
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Journal Article
Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage
Mancikova, Veronika, Pesova, Michaela, Pavlova, Sarka, Helma, Robert, Zavacka, Kristyna, Hejret, Vaclav, Taus, Petr, Hynst, Jakub, Plevova, Karla, Malcikova, Jitka, Pospisilova, Sarka
Published in Molecular oncology (01.01.2023)
Published in Molecular oncology (01.01.2023)
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The Absence of Retroelement Activity Is Characteristic for Childhood Acute Leukemias and Adult Acute Lymphoblastic Leukemia
Urazbakhtin, Shamil, Smirnova, Anastasia, Volakhava, Anastasiya, Zerkalenkova, Elena, Salyutina, Maria, Doubek, Michael, Jelinkova, Hana, Khudainazarova, Nelly, Volchkov, Egor, Belyaeva, Laima, Komech, Ekaterina, Pavlova, Sarka, Lebedev, Yuri, Plevova, Karla, Olshanskaya, Yulia, Komkov, Alexander, Mamedov, Ilgar
Published in International journal of molecular sciences (03.02.2022)
Published in International journal of molecular sciences (03.02.2022)
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Journal Article
ROR1‐based immunomagnetic protocol allows efficient separation of CLL and healthy B cells
Kotašková, Jana, Pavlová, Šárka, Greif, Igor, Stehlíková, Olga, Plevová, Karla, Janovská, Pavlína, Brychtová, Yvona, Doubek, Michael, Pospíšilová, Šárka, Bryja, Vítězslav
Published in British journal of haematology (01.10.2016)
Published in British journal of haematology (01.10.2016)
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Journal Article
ToTem: a tool for variant calling pipeline optimization
Tom, Nikola, Tom, Ondrej, Malcikova, Jitka, Pavlova, Sarka, Kubesova, Blanka, Rausch, Tobias, Kolarik, Miroslav, Benes, Vladimir, Bystry, Vojtech, Pospisilova, Sarka
Published in BMC bioinformatics (26.06.2018)
Published in BMC bioinformatics (26.06.2018)
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Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells
Dave, Zankruti, Vondálová Blanářová, Olga, Čada, Štěpán, Janovská, Pavlína, Zezula, Nikodém, Běhal, Martin, Hanáková, Kateřina, Ganji, Sri Ranjani, Krejci, Pavel, Gömöryová, Kristína, Peschelová, Helena, Šmída, Michal, Zdráhal, Zbyněk, Pavlová, Šárka, Kotašková, Jana, Pospíšilová, Šárka, Bryja, Vítězslav
Published in Frontiers in cell and developmental biology (28.02.2022)
Published in Frontiers in cell and developmental biology (28.02.2022)
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Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones
Plevova, Karla, Francova, Hana Skuhrova, Burckova, Katerina, Brychtova, Yvona, Doubek, Michael, Pavlova, Sarka, Malcikova, Jitka, Mayer, Jiri, Tichy, Boris, Pospisilova, Sarka
Published in Haematologica (Roma) (01.02.2014)
Published in Haematologica (Roma) (01.02.2014)
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Realizing precision medicine in chronic lymphocytic leukemia: Remaining challenges and potential opportunities
Stamatopoulos, Kostas, Pavlova, Sarka, Al‐Sawaf, Othman, Chatzikonstantinou, Thomas, Karamanidou, Christina, Gaidano, Gianluca, Cymbalista, Florence, Kater, Arnon P., Rawstron, Andy, Scarfò, Lydia, Ghia, Paolo, Rosenquist, Richard
Published in HemaSphere (01.07.2024)
Published in HemaSphere (01.07.2024)
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ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin
Navrkalova, Veronika, Sebejova, Ludmila, Zemanova, Jana, Kminkova, Jana, Kubesova, Blanka, Malcikova, Jitka, Mraz, Marek, Smardova, Jana, Pavlova, Sarka, Doubek, Michael, Brychtova, Yvona, Potesil, David, Nemethova, Veronika, Mayer, Jiri, Pospisilova, Sarka, Trbusek, Martin
Published in Haematologica (Roma) (01.07.2013)
Published in Haematologica (Roma) (01.07.2013)
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TP53 Mutation Analysis in Clinical Practice: Lessons From Chronic Lymphocytic Leukemia
Malcikova, Jitka, Pavlova, Sarka, Kozubik, Katerina Stano, Pospisilova, Sarka
Published in Human mutation (01.06.2014)
Published in Human mutation (01.06.2014)
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Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients
Navrkalova, Veronika, Plevova, Karla, Radova, Lenka, Porc, Jakub, Pal, Karol, Malcikova, Jitka, Pavlova, Sarka, Doubek, Michael, Panovska, Anna, Kotaskova, Jana, Pospisilova, Sarka
Published in British journal of haematology (01.01.2024)
Published in British journal of haematology (01.01.2024)
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Journal Article
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options
Malcikova, Jitka, Pavlova, Sarka, Kunt Vonkova, Barbara, Radova, Lenka, Plevova, Karla, Kotaskova, Jana, Pal, Karol, Dvorackova, Barbara, Zenatova, Marcela, Hynst, Jakub, Ondrouskova, Eva, Panovska, Anna, Brychtova, Yvona, Zavacka, Kristyna, Tichy, Boris, Tom, Nikola, Mayer, Jiri, Doubek, Michael, Pospisilova, Sarka
Published in Blood (23.12.2021)
Published in Blood (23.12.2021)
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Detection and Functional Analysis of TP53 Mutations in CLL
Pavlova, Sarka, Smardova, Jana, Tom, Nikola, Trbusek, Martin
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Journal Article
Casein kinase 1 is a therapeutic target in chronic lymphocytic leukemia
Janovska, Pavlina, Verner, Jan, Kohoutek, Jiri, Bryjova, Lenka, Gregorova, Michaela, Dzimkova, Marta, Skabrahova, Hana, Radaszkiewicz, Tomasz, Ovesna, Petra, Vondalova Blanarova, Olga, Nemcova, Tereza, Hoferova, Zuzana, Vasickova, Katerina, Smyckova, Lucie, Egle, Alexander, Pavlova, Sarka, Poppova, Lucie, Plevova, Karla, Pospisilova, Sarka, Bryja, Vitezslav
Published in Blood (15.03.2018)
Published in Blood (15.03.2018)
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Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)
Mihalyova, Jana, Panovska, Anna, Simkovic, Martin, Turcsanyi, Peter, Spacek, Martin, Brejcha, Martin, Lysak, Daniel, Mocikova, Heidi, Pavlova, Sarka, Chrapava, Marika, Zuchnicka, Jana, Brychtova, Yvona, Vodarek, Pavel, Urbanova, Renata, Likarova, Tereza, Malcikova, Jitka, Jurkova, Tereza, Lancova, Klara, Bezdekova, Lucie, Papajik, Tomas, Baranova, Jana, Arpas, Tomas, Pospisilova, Sarka, Smolej, Lukas, Doubek, Michael
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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