Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40
Yang, Haijuan, Jiang, Xiaolu, Li, Buren, Yang, Hyo J., Miller, Meredith, Yang, Angela, Dhar, Ankita, Pavletich, Nikola P.
Published in Nature (London) (21.12.2017)
Published in Nature (London) (21.12.2017)
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Structure of the FA core ubiquitin ligase closing the ID clamp on DNA
Wang, Shengliu, Wang, Renjing, Peralta, Christopher, Yaseen, Ayat, Pavletich, Nikola P.
Published in Nature structural & molecular biology (01.03.2021)
Published in Nature structural & molecular biology (01.03.2021)
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Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes
Takai, Hiroyuki, Xie, Yihu, de Lange, Titia, Pavletich, Nikola P
Published in Genes & development (15.09.2010)
Published in Genes & development (15.09.2010)
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Structural Basis of UV DNA-Damage Recognition by the DDB1–DDB2 Complex
Scrima, Andrea, Koníčková, Renata, Czyzewski, Bryan K., Kawasaki, Yusuke, Jeffrey, Philip D., Groisman, Regina, Nakatani, Yoshihiro, Iwai, Shigenori, Pavletich, Nikola P., Thomä, Nicolas H.
Published in Cell (26.12.2008)
Published in Cell (26.12.2008)
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Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression
Trotman, Lloyd C., Wang, Xinjiang, Alimonti, Andrea, Chen, Zhenbang, Teruya-Feldstein, Julie, Yang, Haijuan, Pavletich, Nikola P., Carver, Brett S., Cordon-Cardo, Carlos, Erdjument-Bromage, Hediye, Tempst, Paul, Chi, Sung-Gil, Kim, Hyo-Jong, Misteli, Tom, Jiang, Xuejun, Pandolfi, Pier Paolo
Published in Cell (12.01.2007)
Published in Cell (12.01.2007)
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Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1
Wang, Renjing, Persky, Nicole S., Yoo, Barney, Ouerfelli, Ouathek, Smogorzewska, Agata, Elledge, Stephen J., Pavletich, Nikola P.
Published in Science (American Association for the Advancement of Science) (28.11.2014)
Published in Science (American Association for the Advancement of Science) (28.11.2014)
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The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
Pavletich, Nikola P, Yang, Haijuan, Li, Qiubai, Fan, Jie, Holloman, William K
Published in Nature (10.02.2005)
Published in Nature (10.02.2005)
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BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure
Yang, Haijuan, Jeffrey, Philip D., Miller, Julie, Kinnucan, Elspeth, Sun, Yutong, Thomä, Nicolas H., Zheng, Ning, Chen, Phang-Lang, Lee, Wen-Hwa, Pavletich, Nikola P.
Published in Science (American Association for the Advancement of Science) (13.09.2002)
Published in Science (American Association for the Advancement of Science) (13.09.2002)
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DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex
Wang, Renjing, Wang, Shengliu, Dhar, Ankita, Peralta, Christopher, Pavletich, Nikola P.
Published in Nature (London) (01.04.2020)
Published in Nature (London) (01.04.2020)
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Journal Article
mTOR kinase structure, mechanism and regulation
Yang, Haijuan, Rudge, Derek G., Koos, Joseph D., Vaidialingam, Bhamini, Yang, Hyo J., Pavletich, Nikola P.
Published in Nature (London) (09.05.2013)
Published in Nature (London) (09.05.2013)
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