Pharmacodynamics of selective inhibition of γ-secretase by avagacestat
Albright, Charles F, Dockens, Randy C, Meredith, Jr, Jere E, Olson, Richard E, Slemmon, Randy, Lentz, Kimberley A, Wang, Jun-Sheng, Denton, R Rex, Pilcher, Gary, Rhyne, Paul W, Raybon, Joseph J, Barten, Donna M, Burton, Catherine, Toyn, Jeremy H, Sankaranarayanan, Sethu, Polson, Craig, Guss, Valerie, White, Randy, Simutis, Frank, Sanderson, Thomas, Gillman, Kevin W, Starrett, Jr, John E, Bronson, Joanne, Sverdlov, Oleksandr, Huang, Shu-Pang, Castaneda, Lorna, Feldman, Howard, Coric, Vlad, Zaczek, Robert, Macor, John E, Houston, John, Berman, Robert M, Tong, Gary
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
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Pharmacokinetic equivalence, comparable safety, and immunogenicity of an adalimumab biosimilar product (M923) to Humira in healthy subjects
Hillson, Jan, Mant, Tim, Rosano, Molly, Huntenburg, Carolyn, Alai‐Safar, Mehrshid, Darne, Siddhesh, Palmer, Donna, Pavlova, Borislava G., Doralt, Jennifer, Reeve, Russell, Goel, Niti, Weilert, Doris, Rhyne, Paul W., Chance, Kamali, Caminis, John, Roach, James, Ganguly, Tanmoy
Published in Pharmacology research & perspectives (01.02.2018)
Published in Pharmacology research & perspectives (01.02.2018)
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Immunoassay-based measurement of clinical biomarkers for monitoring changes in nasal cavity
Zhang, Yan J., Luroe, Sherri, Schieber, Frank, Kelsey, Joan, Nabbie, Fizal, Rizzi, Giovanni, Richards, Penny, Weiner, Russell, Rhyne, Paul W.
Published in Journal of pharmaceutical and biomedical analysis (05.12.2009)
Published in Journal of pharmaceutical and biomedical analysis (05.12.2009)
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Characterization and development of a Luminex(®)-based assay for the detection of human IL-23
Rizzi, Giovanni, Zhang, Yan J, Latek, Robert, Weiner, Russell, Rhyne, Paul W
Published in Bioanalysis (01.09.2010)
Published in Bioanalysis (01.09.2010)
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Journal Article
Multiplex Analysis of Intracellular Signaling Pathways in Lymphoid Cells by Microbead Suspension Arrays
Khan, Imran H., Mendoza, Sara, Rhyne, Paul, Ziman, Melanie, Tuscano, Joseph, Eisinger, Dominic, Kung, Hsing-Jien, Luciw, Paul A.
Published in Molecular & cellular proteomics (01.04.2006)
Published in Molecular & cellular proteomics (01.04.2006)
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Epstein-Barr Virus Small RNAs Potentiate Tumorigenicity of Burkitt Lymphoma Cells Independently of an Effect on Apoptosis
Ruf, I K, Rhyne, P W, Yang, C, Cleveland, J L, Sample, J T
Published in Journal of Virology (01.11.2000)
Published in Journal of Virology (01.11.2000)
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Analysis of apoptotic cells using Beadlyte® suspension arrays
RHYNE, Paul W, SCULL, Jason D, STILES, Lynn M, EISINGER, Dominic P
Published in BioTechniques (01.09.2003)
Published in BioTechniques (01.09.2003)
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Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira
Alleyn, Matthew, Closson, Kristin, Gentile, Adam, Gulbis, Nathan, Taylor, Christopher, Rhyne, Paul
Published in The AAPS journal (03.08.2020)
Published in The AAPS journal (03.08.2020)
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Journal Article
Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development
Jani, Darshana, Allinson, John, Berisha, Flora, Cowan, Kyra J., Devanarayan, Viswanath, Gleason, Carol, Jeromin, Andreas, Keller, Steve, Khan, Masood U., Nowatzke, Bill, Rhyne, Paul, Stephen, Laurie
Published in The AAPS journal (01.01.2016)
Published in The AAPS journal (01.01.2016)
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Recommendations for Selection and Characterization of Protein Biomarker Assay Calibrator Material
Cowan, Kyra J., Amaravadi, Lakshmi, Cameron, Mark J., Fink, Damien, Jani, Darshana, Kamat, Medha, King, Lindsay, Neely, Robert J., Ni, Yan, Rhyne, Paul, Riffon, Renee, Zhu, Yuda
Published in The AAPS journal (01.11.2017)
Published in The AAPS journal (01.11.2017)
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2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays)
Stevenson, Lauren, Richards, Susan, Pillutla, Renuka, Torri, Albert, Kamerud, John, Mehta, Devangi, Keller, Stephen, Purushothama, Shobha, Gorovits, Boris, Litwin, Virginia, Stebbins, Christopher, Marini, Joseph, Beaver, Chris, Sperinde, Gizette, Siguenza, Patricia, Staack, Roland F, Qiu, Yongchang, Amaravadi, Lakshmi, Amur, Shashi, Fleener, Catherine Aversa, Baltrukonis, Daniel, Catlett, Ian, Cherry, Elana, Chung, Shan, Cludts, Isabelle, Donato, Lorella Di, Fischer, Saloumeh, Fraser, Stephanie, Garofolo, Fabio, Green, Cherie, Gunn, George, Haidar, Sam, Haulenbeek, Jonathan, Henderson, Neil, Hopper, Shirley, Ishii-Watabe, Akiko, Islam, Rafiq, Janelsins, Brian, Jawa, Vibha, Kakkanaiah, Vellalore, Kamondi, Szilard, Kolaitis, Gerry, Kubiak, Robert J, Kumar, Seema, Kurki, Pekka, Liang, Meina, Liu, Patrick, Maxfield, Kimberly, Myler, Heather, Palackal, Nisha, Palmer, Rachel, Pedras-Vasconcelos, João, Piccoli, Steven, Rhyne, Paul, Saito, Yoshiro, Savoie, Natasha, Schick, Eginhard, Schweighardt, Becky, Shih, Judy, Song, An, Sriraman, Priya, Staelens, Ludovicus, Sumner, Giane, Sun, Yongliang, Ullmann, Martin, Verthelyi, Daniela, Wadhwa, Meenu, Wang, Yow-Ming, Xu, Yuanxin, Yan, Haoheng, Yang, Tong-yuan, Zeng, Rong
Published in Bioanalysis (01.12.2018)
Published in Bioanalysis (01.12.2018)
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Journal Article
Isolation of Antibody to Human Placental Alkaline Phosphatase (PLAP) from Extracts of Human Placentae
Freeman, Jennifer L., Rhyne, Paul W., Dean, Deyrick O., Beard, G. Alan, Doellgast, George J.
Published in American journal of reproductive immunology (1989) (01.08.2001)
Published in American journal of reproductive immunology (1989) (01.08.2001)
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Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development
Khan, Masood U, Bowsher, Ronald R, Cameron, Mark, Devanarayan, Viswanath, Keller, Steve, King, Lindsay, Lee, Jean, Morimoto, Alyssa, Rhyne, Paul, Stephen, Laurie, Wu, Yuling, Wyant, Timothy, Lachno, D Richard
Published in Bioanalysis (2015)
Published in Bioanalysis (2015)
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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity)
Richards, Susan, Amaravadi, Lakshmi, Pillutla, Renuka, Birnboeck, Herbert, Torri, Albert, Cowan, Kyra J, Papadimitriou, Apollon, Garofolo, Fabio, Satterwhite, Christina, Piccoli, Steven, Wu, Bonnie, Krinos-Fiorotti, Corinna, Allinson, John, Berisha, Flora, Cocea, Laurent, Croft, Stephanie, Fraser, Stephanie, Galliccia, Fabrizio, Gorovits, Boris, Gupta, Swati, Gupta, Vinita, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jani, Darshana, Kadavil, John, Kamerud, John, Kramer, Daniel, Litwin, Virginia, Lima Santos, Gustavo Mendes, Nelson, Robert, Ni, Yan, Pedras-Vasconcelos, João, Qiu, Yongchang, Rhyne, Paul, Safavi, Afshin, Saito, Yoshiro, Savoie, Natasha, Scheibner, Kara, Schick, Eginhard, Siguenza, Patricia Y, Smeraglia, John, Staack, Roland F, Subramanyam, Meena, Sumner, Giane, Thway, Theingi, Uhlinger, David, Ullmann, Martin, Vitaliti, Alessandra, Welink, Jan, Whiting, Chan C, Xue, Li, Zeng, Rong
Published in Bioanalysis (01.12.2016)
Published in Bioanalysis (01.12.2016)
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GCC Consolidated Feedback to ICH on the 2019 ICH M10 Bioanalytical Method Validation Draft Guideline
Nehls, Corey, Buonarati, Michael, Cape, Stephanie, Islam, Rafiq, Satterwhite, Christina, Briscoe, Chad, Hayes, Roger, Dinan, Andrew, Sales, Kurt, Anderson, Shelby, Vance, Jennifer, Lindsay, John, Zimmer, Jennifer, Couerbe, Philippe, Khadang, Ardeshir, Maasjo, Sarah, Bravo, Orlando, Lindley, Kathie, Moran, Liam, Sangster, Timothy, Vija, Jenifer, Stamatopoulos, John, Lin, Jenny, Reuschel, Scott, Underberg, Angie, MacNeill, Robert, Matassa, Luca, Spytko, Adriane, Garofolo, Wei, Savoie, Natasha, Rhyne, Paul, Ambrosius, Jason, Barra, Valentine, Dufield, Dawn, Luna, Marsha, Spriggs, Franklin, Fedorov, Evgueni, Ritzén, Hanna, Fatmi, Saadya, Kane, Cheikh, Bouhajib, Mohammed, DiMarco, Chantal, Iordachescu, Adriana, Tudoroniu, Ariana, Farley, Esme, Stouffer, Bruce, Tabler, Edward, McCown, Stacie, Bower, Joseph, Harrison, Travis, Karnik, Shane, Brown, Michael, Joyce, Philip, DuBey, Ira, Hoffpauir, Brian, Boudreau, Nadine, Bergeron, Jerome, Wang, Hao, Feng, Hao, Zhou, Shaolian, Wells, Edward, Pirro, John, Fang, Xinping, Shi, Jing, Yang, Changming
Published in Bioanalysis (01.09.2019)
Published in Bioanalysis (01.09.2019)
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12th GCC Closed Forum: critical reagents; oligonucleotides; CoA; method transfer; HRMS; flow cytometry; regulatory findings; stability and immunogenicity
Briscoe, Chad, Hughes, Nicola, Hayes, Roger, Islam, Rafiq, Bennett, Patrick, Stouffer, Bruce, Cape, Stephanie, Rhyne, Paul, Beaver, Chris, Charles, Jessica St, Kakkanaiah, Vellalore, Xu, Allan, Caturla, Maria Cruz, Spriggs, Franklin, Tayyem, Rabab, Barry, Colin, Keyhani, Anahita, Zimmer, Jennifer, Couerbe, Philippe, Warren, Mark, Khadang, Ardeshir, Bourdage, James, Lindley, Kathie, Williams, Dave, Sheldon, Curtis, Satterwhite, Christina, Vija, Jenifer, Yu, Mathilde, Boulay, Iohann, Stamatopoulos, John, Lin, Jenny, Estdale, Sian, Thomas, Eric, Dinan, Andrew, MacNeill, Robert, Xiao, Yi Qun, Matassa, Luca, Garofolo, Wei, Savoie, Natasha, Hristopoulos, George, Xu, Arron, Goodwin, Lawrence, Awaiye, Kayode, Ritzén, Hanna, Bouhajib, Mohammed, Marco, Chantal Di, Savu, Simona Rizea, Nehls, Corey, Tabler, Edward, Hays, Amanda, Karnik, Shane, Brown, Michael, Lowes, Steve, DuBey, Ira, Kulagina, Nadia, Lindsay, John, Williard, Clark, Wang, Hao, Malone, Michele, Wells, Edward, Fang, Xinping, Moussallie, Marc
Published in Bioanalysis (01.06.2019)
Published in Bioanalysis (01.06.2019)
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Recommendations for classification of commercial LBA kits for biomarkers in drug development from the GCC for bioanalysis
Islam, Rafiq, Kar, Sumit, Ritzén, Hanna, Hays, Amanda, Tayyem, Rabab, Barry, Colin, Keyhani, Anahita, Zimmer, Jennifer, Caturla, Maria Cruz, Couerbe, Philippe, Warren, Mark, Khadang, Ardeshir, Bourdage, James, Lindley, Kathie, Williams, Dave, Hughes, Nicola, Sheldon, Curtis, Satterwhite, Christina, Vija, Jenifer, Yu, Mathilde, Boulay, Iohann, Stamatopoulos, John, Lin, Jenny, Cape, Stephanie, Estdale, Sian, Thomas, Eric, Dinan, Andrew, MacNeill, Robert, Xiao, Yi Qun, Garofolo, Wei, Savoie, Natasha, Brown, Michael, Rhyne, Paul, Hristopoulos, George, Xu, Arron, Goodwin, Lawrence, Spriggs, Franklin, Xu, Allan, Awaiye, Kayode, Hayes, Roger, Charles, Jessica St, Bouhajib, Mohammed, Silvestro, Luigi, Savu, Simona Rizea, Bennett, Patrick, Kakkanaiah, Vellalore, Nehls, Corey, Stouffer, Bruce, Tabler, Edward, Briscoe, Chad, Karnik, Shane, DuBey, Ira, Kulagina, Nadia, Lindsay, John, Beaver, Chris, Williard, Clark, Wang, Hao, Feng, Hao, Malone, Michele, Wells, Edward, Fang, Xinping, Moussallie, Marc
Published in Bioanalysis (01.04.2019)
Published in Bioanalysis (01.04.2019)
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Journal Article
Fully automated BETA-AMYLOID 42 and tau assays on the enhanced chemiluminescent VITROS® ECiQ Immunodiagnostic System
Baburina, Irina, Contestable, Paul, Courtney, Jodi, Green, George, Jackson, Sherry, Rhyne, Paul, Simon, Adam, Salamone, Salvatore
Published in Alzheimer's & dementia (2013)
Published in Alzheimer's & dementia (2013)
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