Ibrutinib in Previously Treated Waldenström’s Macroglobulinemia
Treon, Steven P, Tripsas, Christina K, Meid, Kirsten, Warren, Diane, Varma, Gaurav, Green, Rebecca, Argyropoulos, Kimon V, Yang, Guang, Cao, Yang, Xu, Lian, Patterson, Christopher J, Rodig, Scott, Zehnder, James L, Aster, Jon C, Harris, Nancy Lee, Kanan, Sandra, Ghobrial, Irene, Castillo, Jorge J, Laubach, Jacob P, Hunter, Zachary R, Salman, Zeena, Li, Jianling, Cheng, Mei, Clow, Fong, Graef, Thorsten, Palomba, M. Lia, Advani, Ranjana H
Published in The New England journal of medicine (09.04.2015)
Published in The New England journal of medicine (09.04.2015)
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Journal Article
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Treon, Steven P, Xu, Lian, Yang, Guang, Zhou, Yangsheng, Liu, Xia, Cao, Yang, Sheehy, Patricia, Manning, Robert J, Patterson, Christopher J, Tripsas, Christina, Arcaini, Luca, Pinkus, Geraldine S, Rodig, Scott J, Sohani, Aliyah R, Harris, Nancy Lee, Laramie, Jason M, Skifter, Donald A, Lincoln, Stephen E, Hunter, Zachary R
Published in The New England journal of medicine (30.08.2012)
Published in The New England journal of medicine (30.08.2012)
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Journal Article
A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia
Yang, Guang, Zhou, Yangsheng, Liu, Xia, Xu, Lian, Cao, Yang, Manning, Robert J., Patterson, Christopher J., Buhrlage, Sara J., Gray, Nathanael, Tai, Yu-Tzu, Anderson, Kenneth C., Hunter, Zachary R., Treon, Steven P.
Published in Blood (15.08.2013)
Published in Blood (15.08.2013)
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Treatment recommendations from the Eighth International Workshop on Waldenström's Macroglobulinemia
Leblond, Véronique, Kastritis, Efstathios, Advani, Ranjana, Ansell, Stephen M., Buske, Christian, Castillo, Jorge J., García-Sanz, Ramón, Gertz, Morie, Kimby, Eva, Kyriakou, Charalampia, Merlini, Giampaolo, Minnema, Monique C., Morel, Pierre, Morra, Enrica, Rummel, Mathias, Wechalekar, Ashutosh, Patterson, Christopher J., Treon, Steven P., Dimopoulos, Meletios A.
Published in Blood (08.09.2016)
Published in Blood (08.09.2016)
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MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction
Xu, Lian, Hunter, Zachary R., Yang, Guang, Zhou, Yangsheng, Cao, Yang, Liu, Xia, Morra, Enrica, Trojani, Alessandra, Greco, Antonino, Arcaini, Luca, Varettoni, Marzia, Brown, Jennifer R., Tai, Yu-Tzu, Anderson, Kenneth C., Munshi, Nikhil C., Patterson, Christopher J., Manning, Robert J., Tripsas, Christina K., Lindeman, Neal I., Treon, Steven P.
Published in Blood (14.03.2013)
Published in Blood (14.03.2013)
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Primary Therapy of Waldenström Macroglobulinemia With Bortezomib, Dexamethasone, and Rituximab: WMCTG Clinical Trial 05-180
TREON, Steven P, LOAKIMIDIS, Leukothea, KEOGH, George P, MYERS, Thomas J, BORAL, Andy, BIRNER, Ann, ESSELTINE, Dixie L, GHOBRIAL, Irene M, SOUMERAI, Jacob D, PATTERSON, Christopher J. J, SHEEHY, Patricia, NELSON, Marybeth, WILLEN, Michael, MATOUS, Jeffrey, MATTERN, John, DIENER, Jakow G
Published in Journal of clinical oncology (10.08.2009)
Published in Journal of clinical oncology (10.08.2009)
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Journal Article
HCK is a survival determinant transactivated by mutated MYD88, and a direct target of ibrutinib
Yang, Guang, Buhrlage, Sara J., Tan, Li, Liu, Xia, Chen, Jie, Xu, Lian, Tsakmaklis, Nicholas, Chen, Jiaji G., Patterson, Christopher J., Brown, Jennifer R., Castillo, Jorge J., Zhang, Wei, Zhang, Xiaofeng, Liu, Shuai, Cohen, Philip, Hunter, Zachary R., Gray, Nathanael, Treon, Steven P.
Published in Blood (23.06.2016)
Published in Blood (23.06.2016)
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MYD88 wild‐type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival
Treon, Steven P., Gustine, Joshua, Xu, Lian, Manning, Robert J., Tsakmaklis, Nicholas, Demos, Maria, Meid, Kirsten, Guerrera, Maria L., Munshi, Manit, Chan, Gloria, Chen, Jiaji, Kofides, Amanda, Patterson, Christopher J., Yang, Guang, Liu, Xia, Severns, Patricia, Dubeau, Toni, Hunter, Zachary R., Castillo, Jorge J.
Published in British journal of haematology (01.02.2018)
Published in British journal of haematology (01.02.2018)
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Natural history of Waldenström macroglobulinemia following acquired resistance to ibrutinib monotherapy
Gustine, Joshua N, Sarosiek, Shayna, Flynn, Catherine A, Meid, Kirsten, Leventoff, Carly, White, Timothy, Guerrera, Maria Luisa, Xu, Lian, Kofides, Amanda, Tsakmaklis, Nicholas, Munshi, Manit, Demos, Maria, Patterson, Christopher J, Liu, Xia, Yang, Guang, Hunter, Zachary R, Branagan, Andrew R, Treon, Steven P, Castillo, Jorge J
Published in Haematologica (Roma) (01.05.2022)
Published in Haematologica (Roma) (01.05.2022)
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MYD88 mutated and wild-type Waldenström's Macroglobulinemia: characterization of chromosome 6q gene losses and their mutual exclusivity with mutations in CXCR4
Guerrera, Maria Luisa, Tsakmaklis, Nickolas, Xu, Lian, Yang, Guang, Demos, Maria, Kofides, Amanda, Chan, Gloria G, Manning, Robert J, Liu, Xia, Chen, Jiaji G, Munshi, Manit, Patterson, Christopher J, Castillo, Jorge J, Dubeau, Toni, Gustine, Joshua, Carrasco, Ruben D, Arcaini, Luca, Varettoni, Marzia, Cazzola, Mario, Treon, Steven P, Hunter, Zachary R
Published in Haematologica (Roma) (01.09.2018)
Published in Haematologica (Roma) (01.09.2018)
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Increased Incidence of Transformation and Myelodysplasia/Acute Leukemia in Patients With Waldenström Macroglobulinemia Treated With Nucleoside Analogs
LELEU, Xavier, SOUMERAI, Jacob, MOREAU, Anne-Sophie, PATTERSON, Christopher J, GHOBRIAL, Irene M, TREON, Steven P, ROCCARO, Aldo, HATJIHARISSI, Evdoxia, HUNTER, Zachary R, MANNING, Robert, CICCARELLI, Bryan T, SACCO, Antonio, IOAKIMIDIS, Leukothea, ADAMIA, Sophia
Published in Journal of clinical oncology (10.01.2009)
Published in Journal of clinical oncology (10.01.2009)
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Journal Article
CXCL13 levels are elevated in patients with Waldenström macroglobulinemia, and are predictive of major response to ibrutinib
Vos, Josephine M, Tsakmaklis, Nickolas, Patterson, Christopher J, Meid, Kirsten, Castillo, Jorge J, Brodsky, Philip, Ganz, Tomas, Pals, Steven T, Kersten, Marie José, Xu, Lian, Yang, Guang, Treon, Steven P, Hunter, Zachary R
Published in Haematologica (Roma) (01.11.2017)
Published in Haematologica (Roma) (01.11.2017)
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Thalidomide and rituximab in Waldenstrom macroglobulinemia
Treon, Steven P., Soumerai, Jacob D., Branagan, Andrew R., Hunter, Zachary R., Patterson, Christopher J., Ioakimidis, Leukothea, Briccetti, Frederick M., Pasmantier, Mark, Zimbler, Harvey, Cooper, Robert B., Moore, Maria, Hill, John, Rauch, Alan, Garbo, Lawrence, Chu, Luis, Chua, Cynthia, Nantel, Stephen H., Lovett, David R., Boedeker, Hans, Sonneborn, Henry, Howard, John, Musto, Paul, Ciccarelli, Bryan T., Hatjiharissi, Evdoxia, Anderson, Kenneth C.
Published in Blood (01.12.2008)
Published in Blood (01.12.2008)
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Journal Article
Lenalidomide and Rituximab in Waldenstrom's Macroglobulinemia
Treon, Steven P, Soumerai, Jacob D, Branagan, Andrew R, Hunter, Zachary R, Patterson, Christopher J, Ioakimidis, Leukothea, Chu, Luis, Musto, Paul, Baron, Ari D, Nunnink, Johannes C, Kash, Joseph J, Terjanian, Terenig O, Hyman, Paul M, Nawfel, Elena L, Sharon, David J, Munshi, Nikhil C, Anderson, Kenneth C
Published in Clinical cancer research (01.01.2009)
Published in Clinical cancer research (01.01.2009)
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CD27-CD70 interactions in the pathogenesis of Waldenström macroglobulinemia
Ho, Allen W., Hatjiharissi, Evdoxia, Ciccarelli, Bryan T., Branagan, Andrew R., Hunter, Zachary R., Leleu, Xavier, Tournilhac, Olivier, Xu, Lian, O'Connor, Kelly, Manning, Robert J., Santos, Daniel Ditzel, Chemaly, Mariana, Patterson, Christopher J., Soumerai, Jacob D., Munshi, Nikhil C., McEarchern, Julie A., Law, Che-Leung, Grewal, Iqbal S., Treon, Steven P.
Published in Blood (01.12.2008)
Published in Blood (01.12.2008)
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Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas
Liu, Xia, Chen, Jiaji G., Munshi, Manit, Hunter, Zachary R., Xu, Lian, Kofides, Amanda, Tsakmaklis, Nickolas, Demos, Maria G., Guerrera, Maria Luisa, Chan, Gloria G., Jimenez, Cristina, Patterson, Christopher J., Meid, Kirsten, Keezer, Andrew, Castillo, Jorge J., Treon, Steven P., Yang, Guang
Published in Blood advances (14.01.2020)
Published in Blood advances (14.01.2020)
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Journal Article
Response and Survival Outcomes to Ibrutinib Monotherapy for Patients With Waldenström Macroglobulinemia on and off Clinical Trials
Castillo, Jorge J., Gustine, Joshua N., Meid, Kirsten, Flynn, Catherine A., Demos, Maria G., Guerrera, Maria L., Jimenez, Cristina, Kofides, Amanda, Liu, Xia, Munshi, Manit, Tsakmaklis, Nicholas, Patterson, Christopher J., Xu, Lian, Yang, Guang, Hunter, Zachary R., Treon, Steven P.
Published in HemaSphere (01.06.2020)
Published in HemaSphere (01.06.2020)
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Journal Article
The genomic landscape of Waldenström macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis
Hunter, Zachary R., Xu, Lian, Yang, Guang, Zhou, Yangsheng, Liu, Xia, Cao, Yang, Manning, Robert J., Tripsas, Christina, Patterson, Christopher J., Sheehy, Patricia, Treon, Steven P.
Published in Blood (13.03.2014)
Published in Blood (13.03.2014)
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Resveratrol Exerts Antiproliferative Activity and Induces Apoptosis in Waldenström's Macroglobulinemia
ROCCARO, Aldo M, LELEU, Xavier, RUSSO, Domenico, VACCA, Angelo, DAMMACCO, Franco, ANDERSON, Kenneth C, GHOBRIAL, Irene M, TREON, Steven P, SACCO, Antonio, MOREAU, Anne-Sophie, HATJIHARISSI, Evdoxia, XIAOYING JIA, LIAN XU, CICCARELLI, Bryan, PATTERSON, Christopher J, NGO, Hait
Published in Clinical cancer research (15.03.2008)
Published in Clinical cancer research (15.03.2008)
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Journal Article
Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia
Treon, Steven P, Meid, Kirsten, Gustine, Joshua, Yang, Guang, Xu, Lian, Liu, Xia, Patterson, Christopher J, Hunter, Zachary R, Branagan, Andrew R, Laubach, Jacob P, Ghobrial, Irene M, Palomba, M Lia, Advani, Ranjana, Castillo, Jorge J
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
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