A framework for deriving analytic steady states of biochemical reaction networks
Hernandez, Bryan S, Lubenia, Patrick Vincent N, Johnston, Matthew D, Kim, Jae Kyoung
Published in PLoS computational biology (01.04.2023)
Published in PLoS computational biology (01.04.2023)
Get full text
Journal Article
Reaction Network Analysis of Metabolic Insulin Signaling
Lubenia, Patrick Vincent N., Mendoza, Eduardo R., Lao, Angelyn R.
Published in Bulletin of mathematical biology (01.11.2022)
Published in Bulletin of mathematical biology (01.11.2022)
Get full text
Journal Article
Comparative analysis of kinetic realizations of insulin signaling
Lubenia, Patrick Vincent N., Mendoza, Eduardo R., Lao, Angelyn R.
Published in Journal of theoretical biology (21.01.2024)
Published in Journal of theoretical biology (21.01.2024)
Get full text
Journal Article
Machine learning and hypothesis driven optimization of bull semen cryopreservation media
Tu, Frankie, Bhat, Maajid, Blondin, Patrick, Vincent, Patrick, Sharafi, Mohsen, Benson, James D.
Published in Scientific reports (25.12.2022)
Published in Scientific reports (25.12.2022)
Get full text
Journal Article
PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib
ENGELMAN, Jeffrey A, ZEJNULLAHU, Kreshnik, ALTHAUS, Irene W, GANDHI, Leena, SHAPIRO, Geoffrey I, NELSON, James M, HEYMACH, John V, MEYERSON, Matthew, WONG, Kwok-Kin, JÄNNE, Pasi A, GALE, Christopher-Michael, LIFSHITS, Eugene, GONZALES, Andrea J, SHIMAMURA, Takeshi, FENG ZHAO, VINCENT, Patrick W, NAUMOV, George N, BRADNER, James E
Published in Cancer research (Chicago, Ill.) (15.12.2007)
Published in Cancer research (Chicago, Ill.) (15.12.2007)
Get full text
Journal Article
Extracting atomic numbers and electron densities from a dual source dual energy CT scanner: Experiments and a simulation model
Landry, Guillaume, Reniers, Brigitte, Granton, Patrick Vincent, van Rooijen, Bart, Beaulieu, Luc, Wildberger, Joachim E, Verhaegen, Frank
Published in Radiotherapy and oncology (01.09.2011)
Published in Radiotherapy and oncology (01.09.2011)
Get full text
Journal Article
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
WILHELM, Scott M, CARTER, Christopher, CAO, Yichen, SHUJATH, Jaleel, GAWLAK, Susan, EVELEIGH, Deepa, ROWLEY, Bruce, LI LIU, ADNANE, Lila, LYNCH, Mark, AUCLAIR, Daniel, TAYLOR, Ian, TANG, Liya, GEDRICH, Rich, VOZNESENSKY, Andrei, RIEDL, Bernd, POST, Leonard E, BOLLAG, Gideon, TRAIL, Pamela A, WILKIE, Dean, MCNABOLA, Angela, HONG RONG, CHEN, Charles, XIAOMEI ZHANG, VINCENT, Patrick, MCHUGH, Mark
Published in Cancer research (Chicago, Ill.) (01.10.2004)
Published in Cancer research (Chicago, Ill.) (01.10.2004)
Get full text
Journal Article
Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor
Gonzales, Andrea J, Hook, Kenneth E, Althaus, Irene W, Ellis, Paul A, Trachet, Erin, Delaney, Amy M, Harvey, Patricia J, Ellis, Teresa A, Amato, Danielle M, Nelson, James M, Fry, David W, Zhu, Tong, Loi, Cho-Ming, Fakhoury, Stephen A, Schlosser, Kevin M, Sexton, Karen E, Winters, R Thomas, Reed, Jessica E, Bridges, Alex J, Lettiere, Daniel J, Baker, Deborah A, Yang, Jianxin, Lee, Helen T, Tecle, Haile, Vincent, Patrick W
Published in Molecular cancer therapeutics (01.07.2008)
Published in Molecular cancer therapeutics (01.07.2008)
Get full text
Journal Article
Optimization of mTOR Inhibitors Using Property-Based Drug Design and Free-Wilson Analysis for Improved In Vivo Efficacy
Murphy, Sean T., Atienza, Joy, Brown, Jason W., Cheruvallath, Zacharia S., Cukierski, Matthew J., Fabrey, Robyn, Keung, Walter, Kwok, Lily, O'Connell, Shawn, Tang, Mingnam, Vanderpool, Darin L., Vincent, Patrick W., Zhang, Lilly, Marx, Matthew A.
Published in ACS medicinal chemistry letters (09.11.2023)
Published in ACS medicinal chemistry letters (09.11.2023)
Get full text
Journal Article
Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants
Micel, Lindsey N, Tentler, John J, Tan, Aik-Choon, Selby, Heather M, Brunkow, Kelsey L, Robertson, Kelli M, Davis, S Lindsey, Klauck, Peter J, Pitts, Todd M, Gangolli, Esha, Fabrey, Robyn, O'Connell, Shawn M, Vincent, Patrick W, Eckhardt, S Gail
Published in Molecular cancer therapeutics (01.02.2015)
Published in Molecular cancer therapeutics (01.02.2015)
Get full text
Journal Article
Treatment outcome and predictors of poor clinical response in extensively drug-resistant gram-negative urinary tract infection among children: A single-institution experience
Batalla-Bocaling, Carren Anne P, Tanseco, Patrick Vincent P, Chua, Michael E
Published in Canadian Urological Association journal (01.03.2021)
Published in Canadian Urological Association journal (01.03.2021)
Get full text
Journal Article
Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs
Vincent, Patrick, Chua, Michael, Nogue, Fabien, Fairbrother, Ashley, Mekeel, Hal, Xu, Yue, Allen, Nina, Bibikova, Tatiana N, Gilroy, Simon, Bankaitis, Vytas A
Published in European journal of cell biology (28.02.2005)
Published in European journal of cell biology (28.02.2005)
Get full text
Journal Article
Evaluation of the therapeutic efficacy of a MEK inhibitor (TAK-733) using 18F-fluorodeoxyglucose-positron emission tomography in the human lung xenograft model A549
Ishino, Seigo, Miyake, Hiroshi, Vincent, Patrick, Mori, Ikuo
Published in Annals of nuclear medicine (01.08.2015)
Published in Annals of nuclear medicine (01.08.2015)
Get full text
Journal Article
Synthesis and structure based optimization of novel Akt inhibitors
Lippa, Blaise, Pan, Gonghua, Corbett, Matthew, Li, Chao, Kauffman, Goss S., Pandit, Jayvardhan, Robinson, Shaughnessy, Wei, Liuqing, Kozina, Ekaterina, Marr, Eric S., Borzillo, Gary, Knauth, Elisabeth, Barbacci-Tobin, Elsa G., Vincent, Patrick, Troutman, Merin, Baker, Deborah, Rajamohan, Francis, Kakar, Shefali, Clark, Tracey, Morris, Joel
Published in Bioorganic & medicinal chemistry (01.06.2008)
Published in Bioorganic & medicinal chemistry (01.06.2008)
Get full text
Journal Article
Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions
Smaill, Jeff B, Rewcastle, Gordon W, Loo, Joseph A, Greis, Kenneth D, Chan, O. Helen, Reyner, Eric L, Lipka, Elke, Showalter, H. D. Hollis, Vincent, Patrick W, Elliott, William L, Denny, William A
Published in Journal of medicinal chemistry (06.04.2000)
Published in Journal of medicinal chemistry (06.04.2000)
Get full text
Journal Article
Trophoblast stem cell marker gene expression in inner cell mass-derived cells from parthenogenetic equine embryos
Desmarais, Joëlle A, Demers, Simon-Pierre, Suzuki, Joao, Laflamme, Simon, Vincent, Patrick, Laverty, Sheila, Smith, Lawrence C
Published in Reproduction (Cambridge, England) (01.03.2011)
Published in Reproduction (Cambridge, England) (01.03.2011)
Get full text
Journal Article