Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer
Matossian, Margarite D, Hoang, Van T, Burks, Hope E, La, Jacqueline, Elliott, Steven, Brock, Courtney, Rusch, Douglas B, Buechlein, Aaron, Nephew, Kenneth P, Bhatt, Akshita, Cavanaugh, Jane E, Flaherty, Patrick T, Collins-Burow, Bridgette M, Burow, Matthew E
Published in Oncoscience (18.05.2021)
Published in Oncoscience (18.05.2021)
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Structure–activity relationships of benzimidazole-based selective inhibitors of the mitogen activated kinase-5 signaling pathway
Flaherty, Patrick T., Chopra, Ishveen, Jain, Prashi, Monlish, Darlene, Cavanaugh, Jane
Published in Bioorganic & medicinal chemistry (15.11.2010)
Published in Bioorganic & medicinal chemistry (15.11.2010)
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Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket
Yuan, Jing, Simpson, Robert D., Zhao, Wei, Tice, Colin M., Xu, Zhenrong, Cacatian, Salvacion, Jia, Lanqi, Flaherty, Patrick T., Guo, Joan, Ishchenko, Alexey, Wu, Zhongren, McKeever, Brian M., Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Panemangalore, Reshma, Bentley, Ross, Doe, Christopher P., Harrison, Richard K., McGeehan, Gerard M., Singh, Suresh B., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
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Design and optimization of renin inhibitors: Orally bioavailable alkyl amines
Tice, Colin M., Xu, Zhenrong, Yuan, Jing, Simpson, Robert D., Cacatian, Salvacion T., Flaherty, Patrick T., Zhao, Wei, Guo, Joan, Ishchenko, Alexey, Singh, Suresh B., Wu, Zhongren, Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Mason, Jennifer, Panemangalore, Reshma, Cappiello, Maria Grazia, Müller, Dominik, Harrison, Richard K., McGeehan, Gerard M., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.
Published in Bioorganic & medicinal chemistry (01.07.2009)
Published in Bioorganic & medicinal chemistry (01.07.2009)
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Abstract B078: Inhibition of the MAPK pathways enhances the sensitivity of triple negative breast cancer cells to chemotherapeutic drugs
Bhatt, Akshita B., Wright, Thomas D., Patel, Saloni, Chakrabarty, Suravi, Barnes, Van, Burow, Matthew, Flaherty, Patrick T., Cavanaugh, Jane
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Abstract 1879: Novel diphenylamine analogs induce mesenchymal to epithelial transition and enhance the sensitivity of breast cancer cells to conventional chemotherapeutic agents
Bhatt, Akshita B., Wright, Thomas D., Anna, Katie, Gupta, Mohit, Chakrabarty, Suravi, Hoang, Van, Burow, Matthew, Flaherty, Patrick T., Cavanaugh, Jane E.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 2392: Evaluation of synergistic PI3K/Akt and MEK5/ERK5 inhibition in triple-negative breast cancer
Wright, Thomas D., Raybuck, Christopher, Gartland, Nathan, Wendekier, Katy, Monlish, Darlene, Chakrabarty, Suravi, Flaherty, Patrick T., Burow, Matthew E., Cavanaugh, Jane E.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Flexible Work Arrangements and Employee Work Attitudes: A Case-Based Inquiry of a Small Non-Profit Response to Crisis
Seal, Craig R, Rawls, Krystal Miguel, Flaherty, Patrick T, Fan, Di, Sanchez, Selina, Guzman, Maria Garcia
Published in Journal of organizational psychology (07.09.2021)
Published in Journal of organizational psychology (07.09.2021)
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Abstract 1963: Analysis of aryl substitution and intramolecular ligand H-bonding in selective inhibitors of the MEK5/ERK5 cascade
Flaherty, Patrick T., Cavanaugh, Jane C., Gupta, Mohit, Vechery, Colin, Chakrabarty, Suravi, Monlish, Darlene, Wright, Thomas
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Compatibility of Various Carbanion Nucleophiles with Heteroaromatic Nucleophilic Substitution by the SRN1 Mechanism
Wong, Jim-Wah, Natalie, Kenneth J, Nwokogu, Godson C, Pisipati, Jyothi S, Flaherty, Patrick T, Greenwood, Thomas D, Wolfe, James F
Published in Journal of organic chemistry (05.09.1997)
Published in Journal of organic chemistry (05.09.1997)
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Abstract 1596: Induction of mesenchymal-to-epithelial transition through pan-MEK inhibition in triple-negative breast cancer
Hoang, Van T., Elliott, Steven, Martin, Elizabeth C., Rhodes, Lyndsay V., Burks, Hope E., Matossian, Margarite, Chakrabarty, Suravi, Monlish, Darlene, Phamduy, Theresa B., Curley, Lowry, Anbalagan, Muralidharan, Rowan, Brian G., Chrisey, Doug, Cavanaugh, Jane E., Flaherty, Patrick T., Collins-Burow, Bridgette M., Burow, Matthew E.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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1-Isopropyl-4-nitro-6-meth-oxy-1H-benzimidazole
Moore, Michael D, Jain, Prashi, Flaherty, Patrick T, Wildfong, Peter L D
Published in Acta crystallographica. Section E, Structure reports online (25.06.2008)
Published in Acta crystallographica. Section E, Structure reports online (25.06.2008)
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Journal Article
1-Isopropyl-4-nitro-6-methoxy-1H-benzimidazole
Michael D. Moore, Prashi Jain, Patrick T. Flaherty, Peter L. D. Wildfong
Published in Acta crystallographica. Section E, Structure reports online (01.07.2008)
Published in Acta crystallographica. Section E, Structure reports online (01.07.2008)
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