Abstract CT039: INDUCE-1: a phase I open-label study of GSK3359609, an ICOS agonist antibody, administered alone and in combination with pembrolizumab in patients with selected, advanced solid tumors
Angevin, Eric, Bauer, Todd M., Ellis, Catherine E., Gan, Hui, Hall, Rigel, Hansen, Aaron, Hoos, Axel, Jewell, Roxanne C., Katz, Jessica, Martin-Liberal, Juan, Maio, Michele, Mayes, Patrick A., Mazumdar, Jolly, Millward, Michael, Rischin, Danny, Schellens, Jan H., Yadavilli, Sapna, Zhou, Helen
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 1637: ICOS agonism induces potent immune activation and anti-tumor response in non-clinical models
Yadavilli, Sapna, Zhang, Tianqian, Hahn, Ashleigh, Seestaller-Wehr, Laura M., Shi, Hong, Liu, Yao-Bin, DeYoung, M.Phillip, Kilian, David J., Bi, Meixia, Adam, Michael P., Zhang, Shu-Yun, Bhattacharya, Sabyasachi, Katlinskaya, Yuliya, Blackwell, Christina, Hopson, Christopher B., Yanamandra, Niranjan, Srinivasan, Roopa, Mayes, Patrick A., Hoos, Axel
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
INDUCE-1: A phase I open-label study of GSK3359609, an ICOS agonist antibody, administered alone and in combination with pembrolizumab in patients with advanced solid tumors
Angevin, Eric, Barnette, Mary S., Bauer, Todd Michael, Cho, Daniel C., Ellis, Catherine Elizabeth, Gan, Hui Kong, Hansen, Aaron Richard, Hoos, Axel, Jewell, Roxanne C, Katz, Jessica, Martin-Liberal, Juan, Maio, Michele, Mayes, Patrick A., Millward, Michael, Moreno, Victor, Olszanski, Anthony J., Rischin, Danny, Schellens, Jan H. M., Yadavilli, Sapna, Zhou, Helen
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Abstract 2936: INCA33890, a novel PD-1×TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1
Wang, Liang-Chuan S., Klooster, Rinse, Kulkarni, Ashwini, de Vinuesa, Amaya Garcia, Soloviev, Maxim, Hendriks, Linda JA, Huo, Lu, Weber, Michael, Mondal, Arpita, Zhao, Yonghong, Harvey, Shane, He, Xin, Chang, Hong, Horsey, April, Volgina, Alla, Zhang, Yue, Pandey, Veethika, Yang, Yan-Ou, Rios-Doria, Jonathan, Eruslanov, Evgeniy, Powell, Daniel J., Albelda, Steven M., de Kruif, John, Nastri, Horacio, Geuijen, Cecile, Mayes, Patrick A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 5031: Effects of BRAF and MEK inhibitors, dabrafenib and trametinib, on the immune system and in combination with immunomodulatory antibodies targeting PD1, PD-L1 and CTLA-4
Liu, Li, Mayes, Patrick, Eastman, Stephen, Shi, Hong, Yadavilli, Sapna, Pan, Xiaoyu, Yang, Jingsong, Seestaller-Wehr, Laura, Zhang, Shu-Yun, Hopson, Chris, Tsvetkov, Lyuben, Jing, Junping, Smothers, James, Pardoll, Drew M., Hoos, Axel
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
Abstract 644: Novel anti-B cell maturation antigen-monomethyl auristatin F antibody-drug conjugate (GSK2857916) induces potent and selective anti-multiple myeloma activity via enhanced effector function and direct tumor cell killing
Tai, Yu-Tzu, Acharya, Chirag, Zhong, Mike Y., Cea, Michele, Cagnetta, Antonia, Mayes, Patrick A., Craigen, Jenny, Gliddon, Louise, Smothers, James, Christie, Amanda L., Kung, Andrew L., Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
Evaluation Of Bcma As a Therapeutic Target In Multiple Myeloma Using An Antibody-Drug Conjugate
Yong, Kwee L, Germaschewski, Fiona M, Rodriguez-Justo, Manuel, Bounds, Danton, Lee, Lydia, Mayes, Patrick A, Sully, Katherine, Seestaller-Wehr, Laura M, Fieles, William E, Tunstead, James R, McCahon, Lee, Paterson, Jennifer, Herledan, Gaelle, Craigen, Jenny L
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Novel Fc-Engineered Anti-B Cell Maturation Antigen-Monomethyl Auristatin F Antibody-Drug Conjugate (GSK2857916) Induces Potent and Selective Anti-Multiple Myeloma Activity Via Enhanced Effector Function and Direct Tumor Cell Killing
Tai, Yu-Tzu, Acharya, Chirag, Zhong, Mike Y, Cea, Michele, Cagnetta, Antonia, Mayes, Patrick A, Craigen, Jenny L, Gliddon, Louise, Smothers, James, Christie, Amanda L, Kung, Andrew L., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Abstract 4502: The small molecule TIC10 has potent anticancer efficacy mediated by induction of TRAIL production in normal and tumor cells
Allen, Joshua E., Krigsfeld, Gabriel, Mayes, Patrick A., Patel, Luv, Dicker, David T., Wu, Gen Sheng, El-Deiry, Wafik S.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Get full text
Journal Article
Abstract 5256: The identification of fatty acid synthase (FASN) as a candidate oncogene and therapeutic target in neuroblastoma
Mayes, Patrick A., Diskin, Sharon, Attiyeh, Edward F., Toporovskaya, Yana, Maris, John M.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Get full text
Journal Article
BCMA (CD269/TNFRSF17)-BINDING PROTEINS
STEPHANIE JANE CLEGG, TREVOR ANTHONY KENNETH WATTAM, ALAN PETER LEWIS, PAUL ALGATE, PATRICK MAYES, JENNIFER L CRAIGEN, PAUL ANDREW HAMBLIN, RADHA SHAH PARMAR
Year of Publication 05.09.2019
Get full text
Year of Publication 05.09.2019
Patent
Abstract C15: Combinatorial regulation of neuroblastoma tumor progression by HIF1α and N-myc transcriptional factors
Qing, Guoliang, Mayes, Patrick, Pawel, Bruce, Martinez, Daniel, Maris, John M., Simon, M. Celeste
Published in Cancer research (Chicago, Ill.) (01.12.2009)
Published in Cancer research (Chicago, Ill.) (01.12.2009)
Get full text
Journal Article
CXCR5 and ICOS expression identifies a CD8 T-cell subset with T FH features in Hodgkin lymphomas
Le, Kieu-Suong, Amé-Thomas, Patricia, Tarte, Karin, Gondois-Rey, Françoise, Granjeaud, Samuel, Orlanducci, Florence, Foucher, Etienne D, Broussais, Florence, Bouabdallah, Reda, Fest, Thierry, Leroux, Dominique, Yadavilli, Sapna, Mayes, Patrick A, Xerri, Luc, Olive, Daniel
Published in Blood advances (14.08.2018)
Get full text
Published in Blood advances (14.08.2018)
Journal Article
Abstract 5467: Breflate upregulates TRAIL gene transcription in Bax-null cells and induces TRAIL-mediated apoptosis independently of p53 in TRAIL-sensitive tumor lines
Allen, Joshua E., Patel, Luv, Krigsfeld, Gabriel, Mayes, Patrick A., Wu, Gen Sheng, El-Deiry, Wafik S.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Get full text
Journal Article
BCMA (CD269/TNFRSF17)-BINDING PROTEINS
STEPHANIE JANE CLEGG, TREVOR ANTHONY KENNETH WATTAM, ALAN PETER LEWIS, PAUL ALGATE, PATRICK MAYES, JENNIFER L CRAIGEN, PAUL ANDREW HAMBLIN, RADHA SHAH PARMAR
Year of Publication 07.06.2018
Get full text
Year of Publication 07.06.2018
Patent