Search Results - "PATRICK AEBISCHER" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

by Ryu, Dongryeol, Mouchiroud, Laurent, Andreux, Pénélope A, Katsyuba, Elena, Moullan, Norman, Nicolet-dit-Félix, Amandine A, Williams, Evan G, Jha, Pooja, Lo Sasso, Giuseppe, Huzard, Damien, Aebischer, Patrick, Sandi, Carmen, Rinsch, Chris, Auwerx, Johan
Published in Nature medicine (01.08.2016)

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Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

by Oueslati, Abid, Schneider, Bernard L, Aebischer, Patrick, Lashuel, Hilal A
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2013)

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The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

by Andreux, Pénélope A, Blanco-Bose, William, Ryu, Dongryeol, Burdet, Frédéric, Ibberson, Mark, Aebischer, Patrick, Auwerx, Johan, Singh, Anurag, Rinsch, Chris
Published in Nature metabolism (01.06.2019)

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Use of viral vectors to create animal models for Parkinson's disease

Use of viral vectors to create animal models for Parkinson's disease

by Löw, Karin, Aebischer, Patrick
Published in Neurobiology of disease (01.11.2012)

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In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

by Mächler, Philipp, Wyss, Matthias T., Elsayed, Maha, Stobart, Jillian, Gutierrez, Robin, von Faber-Castell, Alexandra, Kaelin, Vincens, Zuend, Marc, San Martín, Alejandro, Romero-Gómez, Ignacio, Baeza-Lehnert, Felipe, Lengacher, Sylvain, Schneider, Bernard L., Aebischer, Patrick, Magistretti, Pierre J., Barros, L. Felipe, Weber, Bruno
Published in Cell metabolism (12.01.2016)

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Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

by Kaplan, Artem, Spiller, Krista J, Towne, Christopher, Kanning, Kevin C, Choe, Ginn T, Geber, Adam, Akay, Turgay, Aebischer, Patrick, Henderson, Christopher E
Published in Neuron (Cambridge, Mass.) (22.01.2014)

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Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

by Chu, Yaping, Dodiya, Hemraj, Aebischer, Patrick, Olanow, C. Warren, Kordower, Jeffrey H
Published in Neurobiology of disease (01.09.2009)

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Channel-mediated lactate release by K⁺-stimulated astrocytes

Channel-mediated lactate release by K⁺-stimulated astrocytes

by Sotelo-Hitschfeld, Tamara, Niemeyer, María I, Mächler, Philipp, Ruminot, Iván, Lerchundi, Rodrigo, Wyss, Matthias T, Stobart, Jillian, Fernández-Moncada, Ignacio, Valdebenito, Rocío, Garrido-Gerter, Pamela, Contreras-Baeza, Yasna, Schneider, Bernard L, Aebischer, Patrick, Lengacher, Sylvain, San Martín, Alejandro, Le Douce, Juliette, Bonvento, Gilles, Magistretti, Pierre J, Sepúlveda, Francisco V, Weber, Bruno, Barros, L Felipe
Published in The Journal of neuroscience (11.03.2015)

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Synergistic Effects of GDNF and VEGF on Lifespan and Disease Progression in a Familial ALS Rat Model

Synergistic Effects of GDNF and VEGF on Lifespan and Disease Progression in a Familial ALS Rat Model

by Krakora, Dan, Mulcrone, Patrick, Meyer, Michael, Lewis, Christina, Bernau, Ksenija, Gowing, Genevieve, Zimprich, Chad, Aebischer, Patrick, Svendsen, Clive N, Suzuki, Masatoshi
Published in Molecular therapy (01.08.2013)

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Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

by Lei, Hongxia, Dirren, Elisabeth, Poitry-Yamate, Carole, Schneider, Bernard L, Gruetter, Rolf, Aebischer, Patrick
Published in Journal of cerebral blood flow and metabolism (01.07.2019)

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Recombinant Adeno-Associated Virus Serotype 6 (rAAV2/6)-Mediated Gene Transfer to Nociceptive Neurons through Different Routes of Delivery

Recombinant Adeno-Associated Virus Serotype 6 (rAAV2/6)-Mediated Gene Transfer to Nociceptive Neurons through Different Routes of Delivery

by Towne, Chris, Pertin, Marie, Beggah, Ahmed T, Aebischer, Patrick, Decosterd, Isabelle
Published in Molecular pain (08.09.2009)

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A versatile tool for conditional gene expression and knockdown

A versatile tool for conditional gene expression and knockdown

by Trono, Didier, Aebischer, Patrick, Szulc, Jolanta, Wiznerowicz, Maciej, Sauvain, Marc-Olivier
Published in Nature methods (01.02.2006)

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Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity

Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity

by Bobela, Wojciech, Nazeeruddin, Sameer, Knott, Graham, Aebischer, Patrick, Schneider, Bernard L
Published in Molecular neurodegeneration (03.11.2017)

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A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2

A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2

by Dusonchet, Julien, Kochubey, Olexiy, Stafa, Klodjan, Young, Jr, Samuel M, Zufferey, Romain, Moore, Darren J, Schneider, Bernard L, Aebischer, Patrick
Published in The Journal of neuroscience (19.01.2011)

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GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS

GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS

by Suzuki, Masatoshi, McHugh, Jacalyn, Tork, Craig, Shelley, Brandon, Klein, Sandra M, Aebischer, Patrick, Svendsen, Clive N
Published in PloS one (01.08.2007)

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Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS

by Aebischer, Patrick, Raoul, Cédric, Abbas-Terki, Toufik, Bensadoun, Jean-Charles, Guillot, Sandrine, Haase, Georg, Szulc, Jolanta, Henderson, Christopher E
Published in Nature Medicine (01.04.2005)

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Intracerebroventricular injection of adeno-associated virus 6 and 9 vectors for cell type-specific transgene expression in the spinal cord

Intracerebroventricular injection of adeno-associated virus 6 and 9 vectors for cell type-specific transgene expression in the spinal cord

by Dirren, Elisabeth, Towne, Christopher L, Setola, Veronica, Redmond, Jr, Donald E, Schneider, Bernard L, Aebischer, Patrick
Published in Human gene therapy (01.02.2014)

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Lentiviral Vector Delivery of Parkin Prevents Dopaminergic Degeneration in an α-Synuclein Rat Model of Parkinson's Disease

Lentiviral Vector Delivery of Parkin Prevents Dopaminergic Degeneration in an α-Synuclein Rat Model of Parkinson's Disease

by Lo Bianco, Christophe, Schneider, Bernard L., Bauer, Matthias, Sajadi, Ali, Brice, Alexis, Iwatsubo, Takeshi, Aebischer, Patrick, Gage, Fred H.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2004)

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Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons

Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons

by Ulusoy, Ayse, Sahin, Gurdal, Björklund, Tomas, Aebischer, Patrick, Kirik, Deniz
Published in Molecular therapy (01.09.2009)

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The Krüppel-associated Box Repressor Domain Can Trigger de Novo Promoter Methylation during Mouse Early Embryogenesis

The Krüppel-associated Box Repressor Domain Can Trigger de Novo Promoter Methylation during Mouse Early Embryogenesis

by Wiznerowicz, Maciej, Jakobsson, Johan, Szulc, Jolanta, Liao, Shunyao, Quazzola, Alexandra, Beermann, Friedrich, Aebischer, Patrick, Trono, Didier
Published in The Journal of biological chemistry (23.11.2007)

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