Advancements in mammalian display technology for therapeutic antibody development and beyond: current landscape, challenges, and future prospects
Slavny, Peter, Hegde, Manjunath, Doerner, Achim, Parthiban, Kothai, McCafferty, John, Zielonka, Stefan, Hoet, Rene
Published in Frontiers in immunology (24.09.2024)
Published in Frontiers in immunology (24.09.2024)
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Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries
Dyson, Michael R, Masters, Edward, Pazeraitis, Deividas, Perera, Rajika L, Syrjanen, Johanna L, Surade, Sachin, Thorsteinson, Nels, Parthiban, Kothai, Jones, Philip C, Sattar, Maheen, Wozniak-Knopp, Gordana, Rueker, Florian, Leah, Rachael, McCafferty, John
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing
Parthiban, Kothai, Perera, Rajika L, Sattar, Maheen, Huang, Yanchao, Mayle, Sophie, Masters, Edward, Griffiths, Daniel, Surade, Sachin, Leah, Rachael, Dyson, Michael R, McCafferty, John
Published in mAbs (04.07.2019)
Published in mAbs (04.07.2019)
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Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Aungier, Susan R, Cartwright, Alison J, Schwenzer, Anja, Marshall, Jennifer L, Dyson, Michael R, Slavny, Peter, Parthiban, Kothai, Karatt-Vellatt, Aneesh, Sahbudin, Ilfita, Culbert, Eric, Hextall, Patrick, Clanchy, Felix IL, Williams, Richard, Marsden, Brian D, Raza, Karim, Filer, Andrew, Buckley, Christopher Dominic, McCafferty, John, Midwood, Kim S
Published in Annals of the rheumatic diseases (01.02.2019)
Published in Annals of the rheumatic diseases (01.02.2019)
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Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain
DiCara, Danielle M., Chirgadze, Dimitri Y., Pope, Anthony R., Karatt-Vellatt, Aneesh, Winter, Anja, Slavny, Peter, van den Heuvel, Joop, Parthiban, Kothai, Holland, Jane, Packman, Len C., Mavria, Georgia, Hoffmann, Jens, Birchmeier, Walter, Gherardi, Ermanno, McCafferty, John
Published in Scientific reports (21.08.2017)
Published in Scientific reports (21.08.2017)
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Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells
Falk, Ronny, Falk, Anna, Dyson, Michael R., Melidoni, Anna N., Parthiban, Kothai, Young, Joyce L., Roake, Wendy, McCafferty, John
Published in Methods (San Diego, Calif.) (01.09.2012)
Published in Methods (San Diego, Calif.) (01.09.2012)
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Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses
Bullen, Georgia, Galson, Jacob D, Hall, Gareth, Villar, Pedro, Moreels, Lien, Ledsgaard, Line, Mattiuzzo, Giada, Bentley, Emma M, Masters, Edward W, Tang, David, Millett, Sophie, Tongue, Danielle, Brown, Richard, Diamantopoulos, Ioannis, Parthiban, Kothai, Tebbutt, Claire, Leah, Rachael, Chaitanya, Krishna, Ergueta-Carballo, Sandra, Pazeraitis, Deividas, Surade, Sachin B, Ashiru, Omodele, Crippa, Lucia, Cowan, Richard, Bowler, Matthew W, Campbell, Jamie I, Lee, Wing-Yiu Jason, Carr, Mark D, Matthews, David, Pfeffer, Paul, Hufton, Simon E, Sawmynaden, Kovilen, Osbourn, Jane, McCafferty, John, Karatt-Vellatt, Aneesh
Published in Frontiers in immunology (15.06.2021)
Published in Frontiers in immunology (15.06.2021)
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Response to: ‘Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis’ by Cutolo et al
Aungier, Susan, Cartwright, Alison J, Schwenzer, Anja, Marshall, Jennifer, Dyson, Mike R, Slavny, Peter, Parthiban, Kothai, Karatt-Vellatt, Aneesh, Sahbudin, Ilfita, Culbert, Eric, Hextall, Patrick, Clanchy, Felix IL, Williams, Richard, Marsden, Brian D, Raza, Karim, Filer, Andrew, Buckley, Christopher D, McCafferty, John, Midwood, Kim S
Published in Annals of the rheumatic diseases (01.04.2020)
Published in Annals of the rheumatic diseases (01.04.2020)
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