Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial
Jäger, Ulrich, D'Sa, Shirley, Schörgenhofer, Christian, Bartko, Johann, Derhaschnig, Ulla, Sillaber, Christian, Jilma-Stohlawetz, Petra, Fillitz, Michael, Schenk, Thomas, Patou, Gary, Panicker, Sandip, Parry, Graham C., Gilbert, James C., Jilma, Bernd
Published in Blood (28.02.2019)
Published in Blood (28.02.2019)
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TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins
Shi, Ju, Rose, Eileen L., Singh, Andrew, Hussain, Sami, Stagliano, Nancy E., Parry, Graham C., Panicker, Sandip
Published in Blood (26.06.2014)
Published in Blood (26.06.2014)
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Human secreted tau increases amyloid-beta production
Bright, Jessica, Hussain, Sami, Dang, Vu, Wright, Sarah, Cooper, Bonnie, Byun, Tony, Ramos, Carla, Singh, Andrew, Parry, Graham, Stagliano, Nancy, Griswold-Prenner, Irene
Published in Neurobiology of aging (01.02.2015)
Published in Neurobiology of aging (01.02.2015)
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Specific Inhibition of the Classical Complement Pathway Prevents C3 Deposition along the Dermal-Epidermal Junction in Bullous Pemphigoid
Freire, Patricia Colchete, Muñoz, Cristina Herraez, Derhaschnig, Ulla, Schoergenhofer, Christian, Firbas, Christa, Parry, Graham C., Panicker, Sandip, Gilbert, James C., Stingl, Georg, Jilma, Bernd, Heil, Peter Maximilian
Published in Journal of investigative dermatology (01.12.2019)
Published in Journal of investigative dermatology (01.12.2019)
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Anti-C1s humanized monoclonal antibody SAR445088: A classical pathway complement inhibitor specific for the active form of C1s
Simmons, Ken T., Chan, Joanne, Hussain, Sami, Rose, Eileen L., Markham, Kate, Byun, Tony S., Panicker, Sandip, Parry, Graham C., Storek, Michael
Published in Clinical immunology (Orlando, Fla.) (01.06.2023)
Published in Clinical immunology (Orlando, Fla.) (01.06.2023)
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Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003
Valenzuela, Nicole M, Thomas, Kimberly A, Mulder, Arend, Parry, Graham C, Panicker, Sandip, Reed, Elaine F
Published in Transplantation (01.07.2017)
Published in Transplantation (01.07.2017)
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Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera From Subjects Dosed With the Anti-C1s Monoclonal Antibody TNT009-Results from a Randomized First-in-Human Phase 1 Trial
Mühlbacher, Jakob, Jilma, Bernd, Wahrmann, Markus, Bartko, Johann, Eskandary, Farsad, Schörgenhofer, Christian, Schwameis, Michael, Parry, Graham C, Gilbert, James C, Panicker, Sandip, Böhmig, Georg A
Published in Transplantation (01.10.2017)
Published in Transplantation (01.10.2017)
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Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera from Subjects Dosed with the Anti-C1s Monoclonal Antibody TNT009 - Results from a Randomized First-in-Human Phase 1 Trial
Mühlbacher, Jakob, Jilma, Bernd, Wahrmann, Markus, Bartko, Johann, Eskandary, Farsad, Schörgenhofer, Christian, Schwameis, Michael, Parry, Graham C, Gilbert, James C, Panicker, Sandip, Böhmig, Georg A
Published in Transplantation (01.10.2017)
Published in Transplantation (01.10.2017)
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A non–RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo
Khalili, Parisa, Arakelian, Ani, Chen, Gaoping, Plunkett, Marian L, Beck, Ivy, Parry, Graham C, Doñate, Fernando, Shaw, David E, Mazar, Andrew P, Rabbani, Shafaat A
Published in Molecular cancer therapeutics (01.09.2006)
Published in Molecular cancer therapeutics (01.09.2006)
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Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Huang, Mingdong, Huai, Qing, Zhou, Aiwu, Lin, Lin, Mazar, Andrew P, Parry, Graham C, Callahan, Jennifer, Shaw, David E, Furie, Bruce, Furie, Barbara C
Published in Nature structural & molecular biology (01.04.2008)
Published in Nature structural & molecular biology (01.04.2008)
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Structure of Human Urokinase Plasminogen Activator in Complex with Its Receptor
Huai, Qing, Mazar, Andrew P, Kuo, Alice, Parry, Graham C, Shaw, David E, Callahan, Jennifer, Li, Yongdong, Yuan, Cai, Bian, Chuanbing, Chen, Liqing, Furie, Bruce, Furie, Barbara C, Cines, Douglas B, Huang, Mingdong
Published in Science (American Association for the Advancement of Science) (03.02.2006)
Published in Science (American Association for the Advancement of Science) (03.02.2006)
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Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies
Rumsey, John W., Lorance, Case, Jackson, Max, Sasserath, Trevor, McAleer, Christopher W., Long, Christopher J., Goswami, Arindom, Russo, Melissa A., Raja, Shruti M., Gable, Karissa L., Emmett, Doug, Hobson‐Webb, Lisa D., Chopra, Manisha, Howard, James F., Guptill, Jeffrey T., Storek, Michael J., Alonso‐Alonso, Miguel, Atassi, Nazem, Panicker, Sandip, Parry, Graham, Hammond, Timothy, Hickman, James J.
Published in Advanced therapeutics (01.06.2022)
Published in Advanced therapeutics (01.06.2022)
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Pharmacology of the Novel Antiangiogenic Peptide ATN-161 (Ac-PHSCN-NH2): Observation of a U-Shaped Dose-Response Curve in Several Preclinical Models of Angiogenesis and Tumor Growth
DONATE, Fernando, PARRY, Graham C, KERBEL, Robert S, MAZAR, Andrew P, SHAKED, Yuval, HENSLEY, Harvey, XIAOJUN GUAN, BECK, Ivy, TEL-TSUR, Ziva, PLUNKETT, Marian L, MANUIA, Mari, SHAW, David E
Published in Clinical cancer research (01.04.2008)
Published in Clinical cancer research (01.04.2008)
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Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM)
Xu, Xiang, Cai, Yuan, Wei, Ying, Donate, Fernando, Juarez, Jose, Parry, Graham, Chen, Liqing, Meehan, Edward J, Ahn, Richard W, Ugolkov, Andrey, Dubrovskyi, Oleksii, O'Halloran, Thomas V, Huang, Mingdong, Mazar, Andrew P
Published in PloS one (21.01.2014)
Published in PloS one (21.01.2014)
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Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice
BAUER, Todd W, WENBIAO LIU, BOYD, Douglas D, MAZAR, Andrew P, ELLIS, Lee M, FAN FAN, CAMP, Ernest R, YANG, Anthony, SOMCIO, Ray J, BUCANA, Corazon D, CALLAHAN, Jennifer, PARRY, Graham C, EVANS, Douglas B
Published in Cancer research (Chicago, Ill.) (01.09.2005)
Published in Cancer research (Chicago, Ill.) (01.09.2005)
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