Search Results - "PARLOW, John" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

by Meyers, Marvin J., Pelc, Matthew, Kamtekar, Satwik, Day, Jacqueline, Poda, Gennadiy I., Hall, Molly K., Michener, Marshall L., Reitz, Beverly A., Mathis, Karl J., Pierce, Betsy S., Parikh, Mihir D., Mischke, Deborah A., Long, Scott A., Parlow, John J., Anderson, David R., Thorarensen, Atli
Published in Bioorganic & medicinal chemistry letters (01.03.2010)

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Design, Synthesis, and Crystal Structure of Selective 2-Pyridone Tissue Factor VIIa Inhibitors

Design, Synthesis, and Crystal Structure of Selective 2-Pyridone Tissue Factor VIIa Inhibitors

by Parlow, John J, Kurumbail, Ravi G, Stegeman, Roderick A, Stevens, Anna M, Stallings, William C, South, Michael S
Published in Journal of medicinal chemistry (23.10.2003)

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Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex

Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex

by Parlow, John J, Case, Brenda L, Dice, Thomas A, Fenton, Ricky L, Hayes, Michael J, Jones, Darin E, Neumann, William L, Wood, Rhonda S, Lachance, Rhonda M, Girard, Thomas J, Nicholson, Nancy S, Clare, Michael, Stegeman, Roderick A, Stevens, Anna M, Stallings, William C, Kurumbail, Ravi G, South, Michael S
Published in Journal of medicinal chemistry (11.09.2003)

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Pharmacological Interruption of Acute Thrombus Formation with Minimal Hemorrhagic Complications by a Small Molecule Tissue Factor/Factor VIIa Inhibitor: Comparison to Factor Xa and Thrombin Inhibition in a Nonhuman Primate Thrombosis Model

Pharmacological Interruption of Acute Thrombus Formation with Minimal Hemorrhagic Complications by a Small Molecule Tissue Factor/Factor VIIa Inhibitor: Comparison to Factor Xa and Thrombin Inhibition in a Nonhuman Primate Thrombosis Model

by Suleymanov, Osman D, Szalony, James A, Salyers, Anita K, LaChance, Rhonda M, Parlow, John J, South, Michael S, Wood, Rhonda S, Nicholson, Nancy S
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)

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Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

by PARLOW, John J, BURNEY, Mary W, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A, RAPP, Stephen R
Published in Bioorganic & medicinal chemistry letters (15.08.2009)

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Synthesis of 2-pyridones as tissue factor VIIa inhibitors

Synthesis of 2-pyridones as tissue factor VIIa inhibitors

by Parlow, John J, South, Michael S
Published in Tetrahedron (22.09.2003)

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Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation

Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation

by PARLOW, John J, BURNEY, Mary W, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A, RAPP, Stephen R
Published in Bioorganic & medicinal chemistry letters (01.11.2009)

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Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

by PARLOW, John J, BURNEY, Mary W, RAPP, Stephen R, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HARRIS, Peter K, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A
Published in Bioorganic & medicinal chemistry letters (15.02.2010)

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Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides

Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides

by Parlow, John J, Mischke, Deborah A, Woodard, Scott S
Published in Journal of organic chemistry (22.08.1997)

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Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition

Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition

by Flynn, Daniel L, Crich, Joyce Z, Devraj, Rajesh V, Hockerman, Susan L, Parlow, John J, South, Michael S, Woodard, Scott
Published in Journal of the American Chemical Society (28.05.1997)

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Polymer-Assisted Solution-Phase (PASP) Suzuki Couplings Employing an Anthracene-Tagged Palladium Catalyst

Polymer-Assisted Solution-Phase (PASP) Suzuki Couplings Employing an Anthracene-Tagged Palladium Catalyst

by Lan, Ping, Berta, Daniela, Porco, John A, South, Michael S, Parlow, John J
Published in Journal of organic chemistry (12.12.2003)

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Synthesis and Crystal Structures of Substituted Benzenes and Benzoquinones as Tissue Factor VIIa Inhibitors

Synthesis and Crystal Structures of Substituted Benzenes and Benzoquinones as Tissue Factor VIIa Inhibitors

by Parlow, John J, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, South, Michael S
Published in Journal of medicinal chemistry (25.09.2003)

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Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex

by South, Michael S., Case, Brenda L., Wood, Rhonda S., Jones, Darin E., Hayes, Michael J., Girard, Thomas J., Lachance, Rhonda M., Nicholson, Nancy S., Clare, Michael, Stevens, Anna M., Stegeman, Roderick A., Stallings, William C., Kurumbail, Ravi G., Parlow, John J.
Published in Bioorganic & medicinal chemistry letters (21.07.2003)

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Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue Factor VIIa complex

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue Factor VIIa complex

by PARLOW, John J, KURUMBAIL, Ravi G, STEGEMAN, Roderick A, STEVENS, Anna M, STALLINGS, William C, SOUTH, Michael S
Published in Bioorganic & medicinal chemistry letters (03.11.2003)

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Polymer-Assisted Solution-Phase Library Synthesis and Crystal Structure of α-Ketothiazoles as Tissue Factor VIIa Inhibitors

Polymer-Assisted Solution-Phase Library Synthesis and Crystal Structure of α-Ketothiazoles as Tissue Factor VIIa Inhibitors

by Parlow, John J, Dice, Thomas A, Lachance, Rhonda M, Girard, Thomas J, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, South, Michael S
Published in Journal of medicinal chemistry (11.09.2003)

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In Situ Chemical Tagging: Tetrafluorophthalic Anhydride as a “Sequestration Enabling Reagent” (SER) in the Purification of Solution-Phase Combinatorial Libraries

In Situ Chemical Tagging: Tetrafluorophthalic Anhydride as a “Sequestration Enabling Reagent” (SER) in the Purification of Solution-Phase Combinatorial Libraries

by Parlow, John J, Naing, Win, South, Michael S, Flynn, Daniel L
Published in Tetrahedron letters (17.11.1997)

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High-throughput purification of solution-phase periodinane mediated oxidation reactions utilizing a novel thiosulfate resin

High-throughput purification of solution-phase periodinane mediated oxidation reactions utilizing a novel thiosulfate resin

by Parlow, John J, Case, Brenda L, South, Michael S
Published in Tetrahedron (28.05.1999)

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Polymer-Assisted solution-Phase (PASP) parallel synthesis of an α-Ketothiazole library as tissue factor VIIa inhibitors

Polymer-Assisted solution-Phase (PASP) parallel synthesis of an α-Ketothiazole library as tissue factor VIIa inhibitors

by South, Michael S, Dice, Thomas A, Girard, Thomas J, Lachance, Rhonda M, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, Parlow, John J
Published in Bioorganic & medicinal chemistry letters (21.07.2003)

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Parallel Synthesis and Purification Using Anthracene-Tagged Substrates

Parallel Synthesis and Purification Using Anthracene-Tagged Substrates

by Wang, Xiang, Parlow, John J, Porco, John A
Published in Organic letters (02.11.2000)

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Administration of a small molecule tissue factor/Factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time

Administration of a small molecule tissue factor/Factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time

by Szalony, James A, Suleymanov, Osman D, Salyers, Anita K, Panzer-Knodle, Susan G, Blom, Jason D, LaChance, Rhonda M, Case, Brenda L, Parlow, John J, South, Michael S, Wood, Rhonda S, Nicholson, Nancy S
Published in Thrombosis research (2003)

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