Kidney transplantation from triple‐knockout pigs expressing multiple human proteins in cynomolgus macaques
Ma, David, Hirose, Takayuki, Lassiter, Grace, Sasaki, Hajime, Rosales, Ivy, Coe, Taylor M., Rickert, Charles G., Matheson, Rudy, Colvin, Robert B., Qin, Wenning, Kan, Yinan, Layer, Jacob V., Paragas, Violette B., Stiede, Kathryn, Hall, Katherine C., Youd, Michele E., Queiroz, Luis M., Westlin, William F., Curtis, Michael, Yang, Luhan, Markmann, James F., Kawai, Tatsuo
Published in American journal of transplantation (01.01.2022)
Published in American journal of transplantation (01.01.2022)
Get full text
Journal Article
Design and testing of a humanized porcine donor for xenotransplantation
Anand, Ranjith P., Layer, Jacob V., Heja, David, Hirose, Takayuki, Lassiter, Grace, Firl, Daniel J., Paragas, Violette B., Akkad, Adam, Chhangawala, Sagar, Colvin, Robert B., Ernst, Russell J., Esch, Nicholas, Getchell, Kristen, Griffin, Alexandra K., Guo, Xiaoyun, Hall, Katherine C., Hamilton, Paula, Kalekar, Lokesh A., Kan, Yinan, Karadagi, Ahmad, Li, Feng, Low, Susan C., Matheson, Rudy, Nehring, Claudia, Otsuka, Ryo, Pandelakis, Matthew, Policastro, Robert A., Pols, Rebecca, Queiroz, Luis, Rosales, Ivy A., Serkin, William T., Stiede, Kathryn, Tomosugi, Toshihide, Xue, Yongqiang, Zentner, Gabriel E., Angeles-Albores, David, Chris Chao, J., Crabtree, Juliet N., Harken, Sierra, Hinkle, Nicole, Lemos, Tania, Li, Mailin, Pantano, Lorena, Stevens, Denise, Subedar, Omar D., Tan, Xiaoqing, Yin, Shiyi, Anwar, Imran J., Aufhauser, David, Capuano, Saverio, Kaufman, Dixon B., Knechtle, Stuart J., Kwun, Jean, Shanmuganayagam, Dhanansayan, Markmann, James F., Church, George M., Curtis, Mike, Kawai, Tatsuo, Youd, Michele E., Qin, Wenning
Published in Nature (London) (12.10.2023)
Published in Nature (London) (12.10.2023)
Get full text
Journal Article
Extensive germline genome engineering in pigs
Yue, Yanan, Xu, Weihong, Kan, Yinan, Zhao, Hong-Ye, Zhou, Yixuan, Song, Xiaobin, Wu, Jiajia, Xiong, Juan, Goswami, Dharmendra, Yang, Meng, Lamriben, Lydia, Xu, Mengyuan, Zhang, Qi, Luo, Yu, Guo, Jianxiong, Mao, Shengyi, Jiao, Deling, Nguyen, Tien Dat, Li, Zhuo, Layer, Jacob V., Li, Mailin, Paragas, Violette, Youd, Michele E., Sun, Zhongquan, Ding, Yuan, Wang, Weilin, Dou, Hongwei, Song, Lingling, Wang, Xueqiong, Le, Lei, Fang, Xin, George, Haydy, Anand, Ranjith, Wang, Shi Yun, Westlin, William F., Güell, Marc, Markmann, James, Qin, Wenning, Gao, Yangbin, Wei, Hong-Jiang, Church, George M., Yang, Luhan
Published in Nature biomedical engineering (01.02.2021)
Published in Nature biomedical engineering (01.02.2021)
Get full text
Journal Article
Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis
Schoeberl, Birgit, Pace, Emily A, Fitzgerald, Jonathan B, Harms, Brian D, Xu, Lihui, Nie, Lin, Linggi, Bryan, Kalra, Ashish, Paragas, Violette, Bukhalid, Raghida, Grantcharova, Viara, Kohli, Neeraj, West, Kip A, Leszczyniecka, Magdalena, Feldhaus, Michael J, Kudla, Arthur J, Nielsen, Ulrik B
Published in Science signaling (30.06.2009)
Published in Science signaling (30.06.2009)
Get more information
Journal Article
Predicting ligand-dependent tumors from multi-dimensional signaling features
Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Published in NPJ systems biology and applications (20.09.2017)
Published in NPJ systems biology and applications (20.09.2017)
Get full text
Journal Article
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3
McDonagh, Charlotte F, Huhalov, Alexandra, Harms, Brian D, Adams, Sharlene, Paragas, Violette, Oyama, Shinji, Zhang, Bo, Luus, Lia, Overland, Ryan, Nguyen, Stephanie, Gu, Jinming, Kohli, Neeraj, Wallace, Matt, Feldhaus, Michael J, Kudla, Arthur J, Schoeberl, Birgit, Nielsen, Ulrik B
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
Get full text
Journal Article
Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors
Kirouac, Daniel C, Du, Jin Y, Lahdenranta, Johanna, Overland, Ryan, Yarar, Defne, Paragas, Violette, Pace, Emily, McDonagh, Charlotte F, Nielsen, Ulrik B, Onsum, Matthew D
Published in Science signaling (13.08.2013)
Published in Science signaling (13.08.2013)
Get more information
Journal Article
The ELF-97 Alkaline Phosphatase Substrate Provides a Bright, Photostable, Fluorescent Signal Amplification Method for FISH
Paragas, Violette B, Zhang, Yu-Zhong, Haugland, Richard P, Singer, Victoria L
Published in The journal of histochemistry and cytochemistry (01.03.1997)
Published in The journal of histochemistry and cytochemistry (01.03.1997)
Get full text
Journal Article
Antibody-mediated targeting of TNFR2 activates CD8 + T cells in mice and promotes antitumor immunity
Tam, Eric M, Fulton, Ross B, Sampson, James F, Muda, Marco, Camblin, Adam, Richards, Jennifer, Koshkaryev, Alexander, Tang, Jian, Kurella, Vinodh, Jiao, Yang, Xu, Lihui, Zhang, Kathy, Kohli, Neeraj, Luus, Lia, Hutto, Elizabeth, Kumar, Sandeep, Lulo, James, Paragas, Violette, Wong, Christina, Suchy, James, Grabow, Stephanie, Dugast, Anne-Sophie, Zhang, Hong, Depis, Fabien, Feau, Sonia, Jakubowski, Aniela, Qiao, Wenlian, Craig, Galina, Razlog, Maja, Qiu, James, Zhou, Yu, Marks, James D, Croft, Michael, Drummond, Daryl C, Raue, Andreas
Published in Science translational medicine (02.10.2019)
Published in Science translational medicine (02.10.2019)
Get more information
Journal Article
Single-Cell Quantitative HER2 Measurement Identifies Heterogeneity and Distinct Subgroups within Traditionally Defined HER2-Positive Patients
Onsum, Matthew D, Geretti, Elena, Paragas, Violette, Kudla, Arthur J, Moulis, Sharon P, Luus, Lia, Wickham, Thomas J, McDonagh, Charlotte F, MacBeath, Gavin, Hendriks, Bart S
Published in The American journal of pathology (01.11.2013)
Published in The American journal of pathology (01.11.2013)
Get full text
Journal Article
Abstract 1312: Predicting ligand-dependent tumors from multi-dimensional signaling features
Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 3270: Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity
Fulton, Ross B., Camblin, Adam, Sampson, James F., Richards, Jennifer, Wong, Christina, Koshkaryev, Alexander, Luus, Lia, Jiao, Yang, Xu, Lihui, Paragas, Violette, Razlog, Maja, Muda, Marco, Tam, Eric M., Drummond, Daryl C., Raue, Andreas
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 700: Development of a second-generation TRAIL agonist and predictive biomarker profile for colorectal cancer
Ghassemifar, Sara, Hashambhoy-Ramsay, Yasmin, Yuzugullu, Haluk, Utermark, Tamara, Paragas, Violette, Maiwald, Tim, Luus, Lia, Razlog, Maja, Hudson, Hannah, Chai, Diane, Schoeberl, Birgit, Reynolds, C. Patrick, Sorger, Peter, Sawyer, Andrew J., Drummond, Daryl C., Tam, Eric
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 22: MM-161, a first-in-class pan-FGFR antibody
Dake, Tamara, Finn, Greg, Geddie, Melissa, Kohli, Neeraj, Razlog, Maja, Xu, Lihui, Paragas, Violette, Yuzugullu, Haluk, Ghassemifar, Sara, Hashambhoy-Ramsay, Yasmin, McDonagh, Charlotte, Muda, Marco, Schoeberl, Birgit
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity
Sampson, James F., Kurella, Vinodh B., Paragas, Violette, Kumar, Sandeep, Lulo, James E., Qiu, James A., Razlog, Maja, Fulton, Ross B., Camblin, Adam J., Richards, Jennifer M., Wong, Christina S., Koshkaryev, Alexander, Suchy, James J., Grabow, Stephanie, Muda, Marco, Raue, Andreas, Drummond, Daryl C., Tam, Eric M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 4846: MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memory
Richards, Jennifer, Wong, Christina, Koshkaryev, Alexander, Fulton, Ross, Camblin, Adam, Sampson, James, Luus, Lia, Suchy, James, Grabow, Stephanie, Kurella, Vinodh, Kumar, Sandeep, Lulo, James, Qiu, James, Jiao, Yang, Xu, Lihui, Paragas, Violette, Razlog, Maja, Muda, Marco, Tam, Eric, Raue, Andreas, Drummond, Daryl
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
향상된 이종이식편 생존 및 관용을 위한 하나 이상의 변형된 유전자를 갖는 세포, 조직, 기관, 및 동물
KAN YINAN, HEJA DAVID, QIN WENNING, LAYER JACOB, PARAGAS VIOLETTE, ANGELES ALBORES DAVID, ERNST RUSSELL, YOUD MICHELE, ANAND RANJITH, CRABTREE JULIET, PERRAT PAOLA
Year of Publication 26.12.2023
Get full text
Year of Publication 26.12.2023
Patent
A novel TNFR2 antibody induces T cell co-stimulation and promotes durable anti-tumor immunity
Sampson, James F, Fulton, Ross B, Kurella, Vinodh B, Richards, Jennifer M, Camblin, Adam J, Wong, Christina S, Koshkaryev, Alexander, Lulo, James E, Qiu, James A, Kumar, Sandeep, Luus, Lia, Jiao, Yang, Suchy, James, Grabow, Stephanie, Paragas, Violette, Razlog, Maja, Xi, Lihui, Muda, Marco, Drummond, Daryl C, Tam, Eric M, Raue, Andreas
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
Get full text
Journal Article
Potential regulators of HER2 activity in HER2-overexpressing gastric and gastroesophageal tumors: Analysis of HER3 and heregulin expression
Kudla, Arthur J., Paragas, Violette, Geretti, Elena, Onsum, Matthew D., McDonagh, Charlotte Fenton
Published in Journal of clinical oncology (20.01.2014)
Published in Journal of clinical oncology (20.01.2014)
Get full text
Journal Article
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)
Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
Published in NPJ systems biology and applications (01.01.2017)
Published in NPJ systems biology and applications (01.01.2017)
Get full text
Journal Article