Phase I first-in-human study of CUDC-101, a multitargeted inhibitor of HDACs, EGFR, and HER2 in patients with advanced solid tumors
Shimizu, Toshio, LoRusso, Patricia M, Papadopoulos, Kyri P, Patnaik, Amita, Beeram, Muralidhar, Smith, Lon S, Rasco, Drew W, Mays, Theresa A, Chambers, Glenda, Ma, Anna, Wang, Jing, Laliberte, Robert, Voi, Maurizio, Tolcher, Anthony W
Published in Clinical cancer research (01.10.2014)
Published in Clinical cancer research (01.10.2014)
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Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin
TOLCHER, Anthony W, MITA, Alain, KEATING, Anne, ANTONIA, Scott, LEWIS, Lionel D, GARRETT, Christopher R, TILL, Elizabeth, DAUD, Adil I, PATNAIK, Amita, PAPADOPOULOS, Kyri, TAKIMOTO, Chris, BARTELS, Pamela
Published in Journal of clinical oncology (10.11.2008)
Published in Journal of clinical oncology (10.11.2008)
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Phase I and Pharmacokinetic Study of CT-322 (BMS-844203), a Targeted Adnectin Inhibitor of VEGFR-2 Based on a Domain of Human Fibronectin
TOLCHER, Anthony W, SWEENEY, Christopher J, EATON, Cheryl, SILVER, Bruce A, MITA, Monica, PAPADOPOULOS, Kyri, PATNAIK, Amita, CHIOREAN, Elena G, MITA, Alain C, SANKHALA, Kamalesh, FURFINE, Eric, GOKEMEIJER, Jochem, IACONO, Lisa
Published in Clinical cancer research (15.01.2011)
Published in Clinical cancer research (15.01.2011)
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A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
Sandhu, Shahneen K., Papadopoulos, Kyri, Fong, Peter C., Patnaik, Amita, Messiou, Christina, Olmos, David, Wang, George, Tromp, Brenda J., Puchalski, Thomas A., Balkwill, Frances, Berns, Birge, Seetharam, Shobha, de Bono, Johann S., Tolcher, Anthony W.
Published in Cancer chemotherapy and pharmacology (01.04.2013)
Published in Cancer chemotherapy and pharmacology (01.04.2013)
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Abstract CT056: A Phase Ia/IIa trial of AVID100, an anti-EGFR antibody-drug conjugate
Lakhani, Nehal, Chandana, Sreenivasa, Tolcher, Anthony, Cole, Yvette, Rivas, Karla, Sinclair, Sandra, Nadler, Paul I., Wood, Debra L., Papadopoulos, Kyri P.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract CT031: COM701 demonstrates preliminary antitumor activity as monotherapy and in combination with nivolumab in patients with advanced solid tumors
Sullivan, Ryan, Rasco, Drew, Lim, Emerson, Sharma, Manish, Shepard, Dale, Patnaik, Amita, Hamilton, Erika, Fleming, Gini, Papadopoulos, Kyri, ElNaggar, Adam, Adewoye, Adeboye Henry, Chmielowski, Bartosz, Dumbrava, Ecaterina, Vaena, Dan
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract A088: Novel anti-EGFR antibody-drug conjugate AVID100: A phase 2a trial in patients with EGFR-overexpressing advanced solid tumors
Melear, Jason, Lakhani, Nehal, O'Shaughnessy, Joyce A, Wilks, Sharon T, Khan, Saad, Chandana, Sree R, Tolcher, Anthony W, Papadopoulos, Kyri P, Cole, Yvette, Rivas, Karla, Ghosh, Ria, Sinclair, Sandra, Lutz, Robert, Nadler, Paul I, Wood, Debra L, Burtness, Barbara
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Evaluation of the effects of food on the single-dose pharmacokinetics of trametinib, a first-in-class MEK inhibitor, in patients with cancer
Cox, Donna S, Papadopoulos, Kyri, Fang, Lei, Bauman, John, LoRusso, Patricia, Tolcher, Anthony, Patnaik, Amita, Pendry, Carolyn, Orford, Keith, Ouellet, Daniele
Published in Journal of clinical pharmacology (01.09.2013)
Published in Journal of clinical pharmacology (01.09.2013)
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Abstract A15: Efficacy of trastuzumab emtansine (T-DM1) in subcutaneous and intracranial patient derived xenograft models of breast cancer metastasis
Nielsen, Carsten H., Nedergaard, Mette K., Kristensen, Lotte K., Knudsen, Camilla S., Wick, Michael J., Papadopoulos, Kyri, Tolcher, Anthony W., Kjaer, Andreas
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract B181: Association of AKT1E17K and PIK3CAH1047R mutations with efficacy of ARQ 092 in vitro, in vivo and in patients
Abbadessa, Giovanni, Yu, Yi, Eathiraj, Sudharshan, Meade, Justin, Wick, Michael J., Tolcher, Anthony, Papadopoulos, Kyri, Saleh, Mansoor, Sachdev, Jasgit, Chai, Feng, Schwartz, Brian
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract 5187: PET imaging of trastuzumab emtansine (T-DM1) drug delivery to intracranial patient derived xenograft (PDX) models of breast cancer metastasis
Nielsen, Carsten Haagen, Nedergaard, Mette K., Kristensen, Lotte K., Knudsen, Camilla S., Wick, Michael J., Papadopoulos, Kyri, Tolcher, Anthony, Kjaer, Andreas
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract LB-197: First-in-human study with ARQ 092, a novel pan AKT-inhibitor: Results from the advanced solid tumors cohorts
Saleh, Mansoor, Papadopoulos, Kyri, Arabnia, Alireza, Patnaik, Amita, Stein, Robin M., Cattaneo, Federica, Abbadessa, Giovanni, Greenberg, Jonathan, Warren, Stephen, Tolcher, Anthony
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract A96: Phase 1 study of HSP90 inhibitor MPC-3100 in subjects with refractory or recurrent cancer
Samlowski, Wolfram E., Papadopoulos, Kyri, Olszanski, Anthony J., Zavitz, Kenton, Cimbora, Daniel M., Shawbell, Siobhan, Balch, Alfred, Mather, Gary, Beelen, Andrew
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract A103: Preliminary results of a phase 1 study of FP-1039 (FGFR1:Fc), a novel antagonist of multiple fibroblast growth factor (FGF) ligands, in patients with advanced malignancies
Tolcher, Anthony, Papadopoulos, Kyri, Agnew, Jim, Marshall, John, Tanzola, Carolyn, Zanghi, Jim, Baker, Kevin P., Keer, Harold N., Patniak, Amita
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Abstract A102: First-in-man, first-in-class, pharmacokinetic and pharmacodynamic phase I clinical trial of a human monoclonal antibody CNTO888 to CC-chemokine ligand 2 (CCL2) / monocyte chemoattractant protein (MCP-1) in patients with advanced solid tumors
Sandhu, Shahneen K., Fong, Peter C., Patnaik, Amita, Papadopoulos, Kyri, Messiou, Christina, Hoare, Susan, Olmos, David, Tromp, Brenda J., Puchalski, Thomas A., Balkwill, Frances, Berns, Birge, Debono, Johann S., Tolcher, Anthony W.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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