Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1
Tardif, Keith D, Rogers, Aaron, Cassiano, Jared, Roth, Bruce L, Cimbora, Daniel M, McKinnon, Rena, Peterson, Ashley, Douce, Thomas B, Robinson, Rosann, Dorweiler, Irene, Davis, Thaylon, Hess, Mark A, Ostanin, Kirill, Papac, Damon I, Baichwal, Vijay, McAlexander, Ian, Willardsen, J Adam, Saunders, Michael, Christophe, Hoarau, Kumar, D Vijay, Wettstein, Daniel A, Carlson, Robert O, Williams, Brandi L
Published in Molecular cancer therapeutics (01.12.2011)
Published in Molecular cancer therapeutics (01.12.2011)
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Journal Article
Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Jones, Andrew J.S, Papac, Damon I, Chin, Edward H, Keck, Rodney, Baughman, Sharon A, Lin, Yvonne S, Kneer, Johannes, Battersby, John E
Published in Glycobiology (Oxford) (01.05.2007)
Published in Glycobiology (Oxford) (01.05.2007)
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Journal Article
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors
Vijay Kumar, D., Hoarau, Christophe, Bursavich, Matthew, Slattum, Paul, Gerrish, David, Yager, Kraig, Saunders, Michael, Shenderovich, Mark, Roth, Bruce L., McKinnon, Rena, Chan, Ashley, Cimbora, Daniel M., Bradford, Chad, Reeves, Leslie, Patton, Scott, Papac, Damon I., Williams, Brandi L., Carlson, Robert O.
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Journal Article
Quantification of recombinant human parathyroid hormone (rhPTH(1-84)) in human plasma by immunoassay: Commercial kit evaluation and validation to support pharmacokinetic studies
Sukovaty, Richard L., Lee, Jean W., Fox, John, Toney, Karen, Papac, Damon I., Grover, Thomas A., Wells, David S.
Published in Journal of pharmaceutical and biomedical analysis (18.09.2006)
Published in Journal of pharmaceutical and biomedical analysis (18.09.2006)
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Journal Article
Direct Analysis of Affinity-Bound Analytes by MALDI/TOF MS
Papac, Damon I, Hoyes, John, Tomer, Kenneth B
Published in Analytical chemistry (Washington) (01.09.1994)
Published in Analytical chemistry (Washington) (01.09.1994)
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Journal Article
Mass spectrometric identification of phosphorylation sites in bleached bovine rhodopsin
Papac, Damon I, Oatis, John E, Crouch, Rosalie K, Knapp, Daniel R
Published in Biochemistry (Easton) (15.06.1993)
Published in Biochemistry (Easton) (15.06.1993)
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Journal Article
Abstract 2628: Antitumor activity of MPC-3100, a synthetic Hsp90 inhibitor, in combination with erlotinib and sorafenib
Baichwal, Vijay R., Brown, Brita, Wettstein, Daniel, Papac, Damon I., Mather, Gary G., Carlson, Robert O.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Combination electrospray-liquid secondary ion mass spectrometry ion source
Papac, Damon I, Schey, Kevin L, Knapp, Daniel R
Published in Analytical chemistry (Washington) (01.08.1991)
Published in Analytical chemistry (Washington) (01.08.1991)
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Journal Article
Abstract LB-393: The cancer metabolism inhibitor MPC-9528 induces tumor regression in xenograft models with multiple dosing schedules by causing rapid and sustained reduction in tumor NAD
Baichwal, Vijay R., Willardsen, Adam J., Lockman, Jeff W., Murphy, Brett J., Gordillo, Ruth, Fleischer, Tracey C., Bradford, Chad L., Papac, Damon I., Mather, Gary G., Carlson, Robert O.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Abstract 3526: Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances antitumor activity in Naprt deficient cancer cells in culture and in xenografts
Fleischer, Tracey C., Baichwal, Vijay R., Boniface, J Jay, Cimbora, Daniel M., DeMie, Lynn, Douce, Thomas B., Gassman, Andrew D., Papac, Damon I., Peterson, Ashley, Robinson, Rosann, Terry-Lorenzo, Ryan T., Carlson, Robert O.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Abstract 577: Basal NAD levels and Nampt expression correlate with in vitro and in vivo sensitivity of tumor cell lines to the Nampt inhibitor MPC-9528
Boniface, J Jay, Baichwal, Vijay R., Cimbora, Daniel M., DeMie, Lynn, Fleischer, Tracey C., Gassman, Andrew D., Ghaffari, Siavash, Green, Jeremy P., Flick, Jeff S., Terry-Lorenzo, Ryan T., Papac, Damon I., Peterson, Ashley, Robinson, Rosann, Carlson, Robert O.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Abstract 3233: Comparative in vitro and in vivo metabolism of MPC-3100, an oral HSP90 inhibitor, in rat, dog, monkey and human
Papac, Damon I., Patton, J Scott, Reeves, Leslie, Bulka, Katrina, DeMie, Lynn, Roman, Orvelin, Bradford, Chad, Kim, Se-Ho, Tangallapally, Rajendra, Trovato, Richard, Markovitz, Benjamin, Bajji, Ashok, Wettstein, Daniel, Baichwal, Vijay, Mather, Gary
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Abstract LB-288: MPI-0486348: A novel inhibitor of nicotinamide phosphoribosyltransferase (Nampt) induces tumor regression in a preclinical model
Fleischer, Tracey C., Baichwal, Vijay R., Bradford, Chad L., Demie, Lynn, Green, Jeremy P., Hess, Mark A., Lockman, Jeffrey W., McKinnon, Rena, Ostanin, Kirill, Papac, Damon I., Reeves, Leslie F., Terry-Lorenzo, Ryan T., Willardsen, J Adam
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis
Papac, Damon I., Briggs, John B., Chin, Edward T., Jones, Andrew J.S.
Published in Glycobiology (Oxford) (01.05.1998)
Published in Glycobiology (Oxford) (01.05.1998)
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Journal Article
Palmitylation of a G-protein coupled receptor. Direct analysis by tandem mass spectrometry
Papac, D I, Thornburg, K R, Büllesbach, E E, Crouch, R K, Knapp, D R
Published in The Journal of biological chemistry (25.08.1992)
Published in The Journal of biological chemistry (25.08.1992)
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Journal Article