Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials
Tran, Hai T, PharmD, Liu, Yuan, PhD, Zurita, Amado J, MD, Lin, Ying, PhD, Baker-Neblett, Katherine L, MBA, Martin, Anne-Marie, PhD, Figlin, Robert A, MD, Hutson, Thomas E, DO, Sternberg, Cora N, MD, Amado, Rafael G, MD, Pandite, Lini N, MD, Heymach, John V, Dr
Published in The lancet oncology (01.08.2012)
Published in The lancet oncology (01.08.2012)
Get full text
Journal Article
Phase II, Open-Label Study of Pazopanib or Lapatinib Monotherapy Compared With Pazopanib Plus Lapatinib Combination Therapy in Patients With Advanced and Recurrent Cervical Cancer
MONK, Bradley J, MAS LOPEZ, Luis, ZARBA, Juan J, OAKNIN, Ana, TARPIN, Carole, TERMRUNGRUANGLERT, Wichai, ALBER, Jacquelyn A, JIE DING, STUTTS, Melissa W, PANDITE, Lini N
Published in Journal of clinical oncology (01.08.2010)
Published in Journal of clinical oncology (01.08.2010)
Get full text
Journal Article
Pazopanib Efficacy in Renal Cell Carcinoma: Evidence for Predictive Genetic Markers in Angiogenesis-Related and Exposure-Related Genes
XU, Chun-Fang, BING, Nan X, RAGONE, Leigh J, WHITTAKER, John C, SPRAGGS, Colin F, CARDON, Lon R, MOOSER, Vincent E, PANDITE, Lini N, BALL, Howard A, RAJAGOPALAN, Dilip, STERNBERG, Cora N, HUTSON, Thomas E, DE SOUZA, Paul, XUE, Zhengyu G, MCCANN, Lauren, KING, Karen S
Published in Journal of clinical oncology (20.06.2011)
Published in Journal of clinical oncology (20.06.2011)
Get full text
Journal Article
small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
Podar, Klaus, Tonon, Giovanni, Sattler, Martin, Tai, Yu-Tzu, LeGouill, Steven, Yasui, Hiroshi, Ishitsuka, Kenji, Kumar, Shaji, Kumar, Rakesh, Pandite, Lini N, Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Get full text
Journal Article
Clinical and Biological Effects of Recombinant Human Interleukin-18 Administered by Intravenous Infusion to Patients with Advanced Cancer
ROBERTSON, Michael J, MIER, James W, JEWELL, Roxanne C, BELL, William N, THURMOND, Linda M, WEISENBACH, Jill, ROBERTS, Suzanne, DAR, Mohammed M, LOGAN, Theodore, ATKINS, Michael, KOON, Henry, KOCH, Kevin M, KATHMAN, Steven, PANDITE, Lini N, OEI, Coreen, KIRBY, Lyndon C
Published in Clinical cancer research (15.07.2006)
Published in Clinical cancer research (15.07.2006)
Get full text
Journal Article
Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
Motzer, Robert J, Hutson, Thomas E, Cella, David, Reeves, James, Hawkins, Robert, Guo, Jun, Nathan, Paul, Staehler, Michael, de Souza, Paul, Merchan, Jaime R, Boleti, Ekaterini, Fife, Kate, Jin, Jie, Jones, Robert, Uemura, Hirotsugu, De Giorgi, Ugo, Harmenberg, Ulrika, Wang, Jinwan, Sternberg, Cora N, Deen, Keith, McCann, Lauren, Hackshaw, Michelle D, Crescenzo, Rocco, Pandite, Lini N, Choueiri, Toni K
Published in The New England journal of medicine (22.08.2013)
Published in The New England journal of medicine (22.08.2013)
Get full text
Journal Article
GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment
Podar, Klaus, Catley, Laurence P., Tai, Yu-Tzu, Shringarpure, Reshma, Carvalho, Pedro, Hayashi, Toshiaki, Burger, Renate, Schlossman, Robert L., Richardson, Paul G., Pandite, Lini N., Kumar, Rakesh, Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.
Published in Blood (01.05.2004)
Published in Blood (01.05.2004)
Get full text
Journal Article
HLA-B57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer
Xu, Chun-Fang, Johnson, Toby, Wang, Xiaojing, Carpenter, Chris, Graves, Alan P, Warren, Liling, Xue, Zhengyu, King, Karen S, Fraser, Dana J, Stinnett, Sandy, Briley, Linda P, Mitrica, Ionel, Spraggs, Colin F, Nelson, Matthew R, Tada, Hiroomi, du Bois, Andreas, Powles, Thomas, Kaplowitz, Neil, Pandite, Lini N
Published in Clinical cancer research (15.03.2016)
Published in Clinical cancer research (15.03.2016)
Get full text
Journal Article
Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of Pazopanib
Maitland, Michael L, Xu, Chun-Fang, Cheng, Yu-Ching, Kistner-Griffin, Emily, Ryan, Kathleen A, Karrison, Theodore G, Das, Soma, Torgerson, Dara, Gamazon, Eric R, Thomeas, Vasiliki, Levine, Matthew R, Wilson, Paul A, Bing, Nan, Liu, Yuan, Cardon, Lon R, Pandite, Lini N, O'Connell, Jeffrey R, Cox, Nancy J, Mitchell, Braxton D, Ratain, Mark J, Shuldiner, Alan R
Published in Clinical cancer research (15.01.2015)
Published in Clinical cancer research (15.01.2015)
Get full text
Journal Article
Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma
Xu, Chun-Fang, Reck, Brian H, Goodman, Vicki L, Xue, Zhengyu, Huang, Lingkang, Barnes, Michael R, Koshy, Beena, Spraggs, Colin F, Mooser, Vincent E, Cardon, Lon R, Pandite, Lini N
Published in Journal of hepatology (01.06.2011)
Published in Journal of hepatology (01.06.2011)
Get full text
Journal Article
Phase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumors
de Jonge, Maja J. A., Hamberg, Paul, Verweij, Jaap, Savage, Shawna, Suttle, A. Benjamin, Hodge, Jeffrey, Arumugham, Thangam, Pandite, Lini N., Hurwitz, Herbert I.
Published in Investigational new drugs (01.06.2013)
Published in Investigational new drugs (01.06.2013)
Get full text
Journal Article
Vascular endothelial growth factor inhibition is not an effective therapeutic strategy for relapsed or refractory multiple myeloma: a phase 2 study of pazopanib (GW786034)
Prince, H. Miles, Hönemann, Dirk, Spencer, Andrew, Rizzieri, David A., Stadtmauer, Edward A., Roberts, Andrew W., Bahlis, Nizar, Tricot, Guido, Bell, Bill, DeMarini, Douglas J., Benjamin Suttle, A., Baker, Katherine L., Pandite, Lini N.
Published in Blood (07.05.2009)
Published in Blood (07.05.2009)
Get full text
Journal Article
HLA-B 57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer
Xu, Chun-Fang, Johnson, Toby, Wang, Xiaojing, Carpenter, Chris, Graves, Alan P., Warren, Liling, Xue, Zhengyu, King, Karen S., Fraser, Dana J., Stinnett, Sandy, Briley, Linda P., Mitrica, Ionel, Spraggs, Colin F., Nelson, Matthew R., Tada, Hiroomi, du Bois, Andreas, Powles, Thomas, Kaplowitz, Neil, Pandite, Lini N.
Published in Clinical cancer research (15.03.2016)
Published in Clinical cancer research (15.03.2016)
Get full text
Journal Article
Assessment of a cell-line-derived HIF1α gene signature in tumor tissue from a metastatic renal cell carcinoma (RCC) trial of pazopanib
Gagnon, Robert C., Liu, Yuan, Choueiri, Toni K., Martin, Anne-Marie, Rosenberg, Jonathan E., Signoretti, Sabina, Pandite, Lini N.
Published in Journal of clinical oncology (10.02.2012)
Published in Journal of clinical oncology (10.02.2012)
Get full text
Journal Article
Abstract A11: Lower baseline levels of plasma hepatocyte growth factor, IL-6, and IL-8 are correlated with greater tumor shrinkage in renal cell carcinoma patients treated with pazopanib
Heymach, John V., Tran, Hai T., Fritsche, Herbert A., Gornet, Terrie G., Liu, Yuan, Rajagopalan, Dilip, Martin, Anne-Marie, Baker, Katherine L., Downie, Louise, Hutson, Thomas E., Figlin, Robert A., Amado, Rafael G., Pandite, Lini N.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
Get full text
Journal Article
The Small-Molecule VEGF-Receptor Inhibitor Pazopanib (GW786034B) Targets Both Tumor and Endothelial Cells in Multiple Myeloma
Podar, Klaus, Tonon, Giovanni, Sattler, Martin, Tai, Yu-Tzu, LeGouill, Steven, Yasui, Hiroshi, Ishitsuka, Kenji, Kumar, Rakesh, Pandite, Lini N., Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
Get full text
Journal Article
Effects of the Indazolylpyrimidine GW786034 on Angiogenesis and MM Cell Growth: Therapeutic Implications
Podar, Klaus, Simoncini, Melissa, Le Gouill, Steven, Tai, Yu-Tzu, Kumar, Shaji, Tassone, Pierfrancesco, Catley, Laurence P., Pandite, Lini N., Kumar, Rakesh, Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
Get full text
Journal Article