Dabrafenib in patients with BRAFV600E -positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial
Planchard, David, MD, Kim, Tae Min, MD, Mazieres, Julien, Prof, Quoix, Elisabeth, Prof, Riely, Gregory, MD, Barlesi, Fabrice, Prof, Souquet, Pierre-Jean, MD, Smit, Egbert F, Prof, Groen, Harry J M, Prof, Kelly, Ronan J, MD, Cho, B C, MD, Socinski, Mark A, Prof, Pandite, Lini, MD, Nase, Christine, BSN, Ma, Bo, PhD, D'Amelio, Anthony, PhD, Mookerjee, Bijoyesh, MD, Curtis, C Martin, BS, Johnson, Bruce E, Prof
Published in The lancet oncology (01.05.2016)
Published in The lancet oncology (01.05.2016)
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Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials
Tran, Hai T, PharmD, Liu, Yuan, PhD, Zurita, Amado J, MD, Lin, Ying, PhD, Baker-Neblett, Katherine L, MBA, Martin, Anne-Marie, PhD, Figlin, Robert A, MD, Hutson, Thomas E, DO, Sternberg, Cora N, MD, Amado, Rafael G, MD, Pandite, Lini N, MD, Heymach, John V, Dr
Published in The lancet oncology (01.08.2012)
Published in The lancet oncology (01.08.2012)
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Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
Motzer, Robert J, Hutson, Thomas E, Cella, David, Reeves, James, Hawkins, Robert, Guo, Jun, Nathan, Paul, Staehler, Michael, de Souza, Paul, Merchan, Jaime R, Boleti, Ekaterini, Fife, Kate, Jin, Jie, Jones, Robert, Uemura, Hirotsugu, De Giorgi, Ugo, Harmenberg, Ulrika, Wang, Jinwan, Sternberg, Cora N, Deen, Keith, McCann, Lauren, Hackshaw, Michelle D, Crescenzo, Rocco, Pandite, Lini N, Choueiri, Toni K
Published in The New England journal of medicine (22.08.2013)
Published in The New England journal of medicine (22.08.2013)
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Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III Trial
Sternberg, Cora N, Davis, Ian D, Mardiak, Jozef, Szczylik, Cezary, Lee, Eunsik, Wagstaff, John, Barrios, Carlos H, Salman, Pamela, Gladkov, Oleg A, Kavina, Alexander, Zarbá, Juan J, Chen, Mei, McCann, Lauren, Pandite, Lini, Roychowdhury, Debasish F, Hawkins, Robert E
Published in Journal of clinical oncology (20.02.2010)
Published in Journal of clinical oncology (20.02.2010)
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Phase II, Open-Label Study of Pazopanib or Lapatinib Monotherapy Compared With Pazopanib Plus Lapatinib Combination Therapy in Patients With Advanced and Recurrent Cervical Cancer
MONK, Bradley J, MAS LOPEZ, Luis, ZARBA, Juan J, OAKNIN, Ana, TARPIN, Carole, TERMRUNGRUANGLERT, Wichai, ALBER, Jacquelyn A, JIE DING, STUTTS, Melissa W, PANDITE, Lini N
Published in Journal of clinical oncology (01.08.2010)
Published in Journal of clinical oncology (01.08.2010)
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Pazopanib, a Multikinase Angiogenesis Inhibitor, in Patients With Relapsed or Refractory Advanced Soft Tissue Sarcoma: A Phase II Study From the European Organisation for Research and Treatment of Cancer–Soft Tissue and Bone Sarcoma Group (EORTC Study 62043)
SLEIJFER, Stefan, RAY-COQUARD, Isabelle, VAN GLABBEKE, Martine, VERWEIJ, Jaap, BLAY, Jean-Yves, PAPAI, Zsuzsa, LE CESNE, Axel, SCURR, Michelle, SCHÖFFSKI, Patrick, COLLIN, Françoise, PANDITE, Lini, MARREAUD, Sandrine, DE BRAUWER, Annick
Published in Journal of clinical oncology (01.07.2009)
Published in Journal of clinical oncology (01.07.2009)
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Phase I Trial of Pazopanib in Patients with Advanced Cancer
Hurwitz, Herbert I, Dowlati, Afshin, Saini, Shermini, Savage, Shawna, Suttle, A Benjamin, Gibson, Diana M, Hodge, Jeffrey P, Merkle, Elmar M, Pandite, Lini
Published in Clinical cancer research (15.06.2009)
Published in Clinical cancer research (15.06.2009)
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Pazopanib Efficacy in Renal Cell Carcinoma: Evidence for Predictive Genetic Markers in Angiogenesis-Related and Exposure-Related Genes
XU, Chun-Fang, BING, Nan X, RAGONE, Leigh J, WHITTAKER, John C, SPRAGGS, Colin F, CARDON, Lon R, MOOSER, Vincent E, PANDITE, Lini N, BALL, Howard A, RAJAGOPALAN, Dilip, STERNBERG, Cora N, HUTSON, Thomas E, DE SOUZA, Paul, XUE, Zhengyu G, MCCANN, Lauren, KING, Karen S
Published in Journal of clinical oncology (20.06.2011)
Published in Journal of clinical oncology (20.06.2011)
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HLA-B57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer
Xu, Chun-Fang, Johnson, Toby, Wang, Xiaojing, Carpenter, Chris, Graves, Alan P, Warren, Liling, Xue, Zhengyu, King, Karen S, Fraser, Dana J, Stinnett, Sandy, Briley, Linda P, Mitrica, Ionel, Spraggs, Colin F, Nelson, Matthew R, Tada, Hiroomi, du Bois, Andreas, Powles, Thomas, Kaplowitz, Neil, Pandite, Lini N
Published in Clinical cancer research (15.03.2016)
Published in Clinical cancer research (15.03.2016)
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Efficacy and Safety of Pazopanib in Patients With Metastatic Renal Cell Carcinoma
HUTSON, Thomas E, DAVIS, Ian D, PANDITE, Lini, FIGLIN, Robert A, MACHIELS, Jean-Pascal H, DE SOUZA, Paul L, ROTTEY, Sylvie, HONG, Bao-Fa, EPSTEIN, Richard J, BAKER, Katherine L, MCCANN, Lauren, CROFTS, Theresa
Published in Journal of clinical oncology (20.01.2010)
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small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
Podar, Klaus, Tonon, Giovanni, Sattler, Martin, Tai, Yu-Tzu, LeGouill, Steven, Yasui, Hiroshi, Ishitsuka, Kenji, Kumar, Shaji, Kumar, Rakesh, Pandite, Lini N, Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
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Clinical and Biological Effects of Recombinant Human Interleukin-18 Administered by Intravenous Infusion to Patients with Advanced Cancer
ROBERTSON, Michael J, MIER, James W, JEWELL, Roxanne C, BELL, William N, THURMOND, Linda M, WEISENBACH, Jill, ROBERTS, Suzanne, DAR, Mohammed M, LOGAN, Theodore, ATKINS, Michael, KOON, Henry, KOCH, Kevin M, KATHMAN, Steven, PANDITE, Lini N, OEI, Coreen, KIRBY, Lyndon C
Published in Clinical cancer research (15.07.2006)
Published in Clinical cancer research (15.07.2006)
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3 Development of an integrated method to quantify receptor occupancy for agonist immunotherapeutics that stimulate target cells to migrate from the peripheral blood
Gonzalez, Louis, Ma, Bo, Hernandez, Robert, McKay, Hannah, Rangwala, Fatima, Pandite, Lini, Schreiber, Taylor
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of Pazopanib
Maitland, Michael L, Xu, Chun-Fang, Cheng, Yu-Ching, Kistner-Griffin, Emily, Ryan, Kathleen A, Karrison, Theodore G, Das, Soma, Torgerson, Dara, Gamazon, Eric R, Thomeas, Vasiliki, Levine, Matthew R, Wilson, Paul A, Bing, Nan, Liu, Yuan, Cardon, Lon R, Pandite, Lini N, O'Connell, Jeffrey R, Cox, Nancy J, Mitchell, Braxton D, Ratain, Mark J, Shuldiner, Alan R
Published in Clinical cancer research (15.01.2015)
Published in Clinical cancer research (15.01.2015)
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A Phase I and Pharmacokinetic Study of Oral Lapatinib Administered Once or Twice Daily in Patients with Solid Malignancies
Burris, 3rd, Howard A, Taylor, Charles W, Jones, Suzanne F, Koch, Kevin M, Versola, Melissa J, Arya, Niki, Fleming, Ronald A, Smith, Deborah A, Pandite, Lini, Spector, Neil, Wilding, George
Published in Clinical cancer research (01.11.2009)
Published in Clinical cancer research (01.11.2009)
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Phase I Dose Escalation and Pharmacokinetic Study of Lapatinib in Combination With Trastuzumab in Patients With Advanced ErbB2-Positive Breast Cancer
STORNIOLO, Anna Maria, PEGRAM, Mark D, PANDITE, Lini, FLEMING, Ronald A, LEBOWITZ, Peter F, HO, Peter T. C, BURRIS, Howard A, OVERMOYER, Beth, SILVERMAN, Paula, PEACOCK, Nancy W, JONES, Suzanne F, LOFTISS, Jill, ARYA, Nikita, KOCH, Kevin M, PAUL, Elaine
Published in Journal of clinical oncology (10.07.2008)
Published in Journal of clinical oncology (10.07.2008)
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Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma
Xu, Chun-Fang, Reck, Brian H, Goodman, Vicki L, Xue, Zhengyu, Huang, Lingkang, Barnes, Michael R, Koshy, Beena, Spraggs, Colin F, Mooser, Vincent E, Cardon, Lon R, Pandite, Lini N
Published in Journal of hepatology (01.06.2011)
Published in Journal of hepatology (01.06.2011)
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Phase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumors
de Jonge, Maja J. A., Hamberg, Paul, Verweij, Jaap, Savage, Shawna, Suttle, A. Benjamin, Hodge, Jeffrey, Arumugham, Thangam, Pandite, Lini N., Hurwitz, Herbert I.
Published in Investigational new drugs (01.06.2013)
Published in Investigational new drugs (01.06.2013)
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A Phase I and Pharmacokinetic Study of Lapatinib in Combination with Letrozole in Patients with Advanced Cancer
Chu, Quincy S C, Cianfrocca, Mary E, Goldstein, Lori J, Gale, Meg, Murray, Nicholas, Loftiss, Jill, Arya, Nikita, Koch, Kevin M, Pandite, Lini, Fleming, Ronald A, Paul, Elaine, Rowinsky, Eric K
Published in Clinical cancer research (15.07.2008)
Published in Clinical cancer research (15.07.2008)
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