Search Results - "PANAYOTIS KATSOYANNIS" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

by Smith, Brian J, Huang, Kun, Kong, Geoffrey, Chan, Shu Jin, Nakagawa, Satoe, Menting, John G, Hu, Shi-Quan, Whittaker, Jonathan, Steiner, Donald F, Katsoyannis, Panayotis G, Ward, Colin W, Weiss, Michael A, Lawrence, Michael C
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2010)

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Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN

Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN

by Yang, Yanwu, Petkova, Aneta, Huang, Kun, Xu, Bin, Hua, Qing-xin, Ye, I. Ju, Chu, Ying-Chi, Hu, Shi-Quan, Phillips, Nelson B, Whittaker, Jonathan, Ismail-Beigi, Faramarz, Mackin, Robert B, Katsoyannis, Panayotis G, Tycko, Robert, Weiss, Michael A
Published in The Journal of biological chemistry (02.04.2010)

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Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS

Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS

by Hua, Qing-xin, Xu, Bin, Huang, Kun, Hu, Shi-Quan, Nakagawa, Satoe, Jia, Wenhua, Wang, Shuhua, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (22.05.2009)

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Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS

Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS

by Xu, Bin, Huang, Kun, Chu, Ying-Chi, Hu, Shi-Quan, Nakagawa, Satoe, Wang, Shuhua, Wang, Run-Ying, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (22.05.2009)

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Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity

Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity

by Liu, Ming, Wan, Zhu-Li, Chu, Ying-Chi, Aladdin, Hassan, Klaproth, Birgit, Choquette, Meredith, Hua, Qing-Xin, Mackin, Robert B, Rao, J Sunil, De Meyts, Pierre, Katsoyannis, Panayotis G, Arvan, Peter, Weiss, Michael A
Published in The Journal of biological chemistry (11.12.2009)

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A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE

A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE

by Huang, Kun, Chan, Shu Jin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Klaproth, Birgit, Jia, Wenhua, Whittaker, Jonathan, De Meyts, Pierre, Nakagawa, Satoe H, Steiner, Donald F, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (30.11.2007)

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Chiral Mutagenesis of Insulin: CONTRIBUTION OF THE B20-B23 β-TURN TO ACTIVITY AND STABILITY

Chiral Mutagenesis of Insulin: CONTRIBUTION OF THE B20-B23 β-TURN TO ACTIVITY AND STABILITY

by Nakagawa, Satoe H, Hua, Qing-xin, Hu, Shi-Quan, Jia, Wenhua, Wang, Shuhua, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (04.08.2006)

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Design of an Insulin Analog with Enhanced Receptor Binding Selectivity: RATIONALE, STRUCTURE, AND THERAPEUTIC IMPLICATIONS

Design of an Insulin Analog with Enhanced Receptor Binding Selectivity: RATIONALE, STRUCTURE, AND THERAPEUTIC IMPLICATIONS

by Zhao, Ming, Wan, Zhu-li, Whittaker, Linda, Xu, Bin, Phillips, Nelson B, Katsoyannis, Panayotis G, Ismail-Beigi, Faramarz, Whittaker, Jonathan, Weiss, Michael A
Published in The Journal of biological chemistry (13.11.2009)

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How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor

by Huang, Kun, Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Hua, Qing-Xin, Qu, Yan, Li, Biaoru, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Theede, Anne Mette, Whittaker, Jonathan, De Meyts, Pierre, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (06.08.2004)

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Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

by Wan, Zhu-li, Huang, Kun, Xu, Bin, Hu, Shi-Quan, Wang, Shuhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (05.04.2005)

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Diabetes-Associated Mutations in Insulin: Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor

Diabetes-Associated Mutations in Insulin: Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor

by Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Huang, Kun, Nakagawa, Satoe H, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (06.07.2004)

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Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing

Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing

by Hua, Qing-Xin, Chu, Ying-Chi, Jia, Wenhua, Phillips, Nelson F B, Wang, Run-Ying, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (08.11.2002)

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Enhancing the Activity of Insulin at the Receptor Interface: Crystal Structure and Photo-Cross-Linking of A8 Analogues

Enhancing the Activity of Insulin at the Receptor Interface: Crystal Structure and Photo-Cross-Linking of A8 Analogues

by Wan, Zhuli, Xu, Bin, Huang, Kun, Chu, Ying-Chi, Li, Biaoru, Nakagawa, Satoe H, Qu, Yan, Hu, Shi-Quan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (28.12.2004)

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Hierarchical Protein Folding: Asymmetric Unfolding of an Insulin Analogue Lacking the A7−B7 Interchain Disulfide Bridge

Hierarchical Protein Folding: Asymmetric Unfolding of an Insulin Analogue Lacking the A7−B7 Interchain Disulfide Bridge

by Hua, Qing-Xin, Nakagawa, Satoe H, Jia, Wenhua, Hu, Shi-Quan, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (16.10.2001)

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Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts

Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts

by Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Diabetes (New York, N.Y.) (01.06.2004)

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Hierarchical Protein “Un-Design”: Insulin's Intrachain Disulfide Bridge Tethers a Recognition α-Helix

Hierarchical Protein “Un-Design”: Insulin's Intrachain Disulfide Bridge Tethers a Recognition α-Helix

by Weiss, Michael A, Hua, Qing-Xin, Jia, Wenhua, Chu, Ying-Chi, Wang, Run-Ying, Katsoyannis, Panayotis G
Published in Biochemistry (Easton) (19.12.2000)

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Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue

Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue

by Xu, Bin, Hua, Qing-xin, Nakagawa, Satoe H, Jia, Wenhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (22.02.2002)

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Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding

Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding

by Wan, Zhu-li, Xu, Bin, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (11.11.2003)

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Protein Structure and the Spandrels of San Marco: Insulin's Receptor-Binding Surface Is Buttressed by an Invariant Leucine Essential for Its Stability

Protein Structure and the Spandrels of San Marco: Insulin's Receptor-Binding Surface Is Buttressed by an Invariant Leucine Essential for Its Stability

by Weiss, Michael A, Nakagawa, Satoe H, Jia, Wenhua, Xu, Bin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Katsoyannis, Panayotis G
Published in Biochemistry (Easton) (22.01.2002)

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Crystal Structure of allo-IleA2-Insulin, an Inactive Chiral Analogue: Implications for the Mechanism of Receptor Binding

Crystal Structure of allo-IleA2-Insulin, an Inactive Chiral Analogue: Implications for the Mechanism of Receptor Binding

by Wan, Zhu-li, Xu, Bin, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (11.11.2003)

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