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Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion
Trivellin, Giampaolo, Daly, Adrian F., Hernández-Ramírez, Laura C., Araldi, Elisa, Tatsi, Christina, Dale, Ryan K., Fridell, Gus, Mittal, Arjun, Faucz, Fabio R., Iben, James R., Li, Tianwei, Vitali, Eleonora, Stojilkovic, Stanko S., Kamenicky, Peter, Villa, Chiara, Baussart, Bertrand, Chittiboina, Prashant, Toro, Camilo, Gahl, William A., Eugster, Erica A., Naves, Luciana A., Jaffrain-Rea, Marie-Lise, de Herder, Wouter W., Neggers, Sebastian JCMM, Petrossians, Patrick, Beckers, Albert, Lania, Andrea G., Mains, Richard E., Eipper, Betty A., Stratakis, Constantine A.
Published in Frontiers in endocrinology (Lausanne) (14.06.2023)
Published in Frontiers in endocrinology (Lausanne) (14.06.2023)
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Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain
Webster, Lynn, Jansen, Jan Peter, Peppin, John, Lasko, Ben, Irving, Gordon, Morlion, Bart, Snidow, Jerry, Pierce, Amy, Mortensen, Eric, Kleoudis, Christi, Carter, Eric
Published in Pain (Amsterdam) (15.07.2008)
Published in Pain (Amsterdam) (15.07.2008)
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Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion
Trivellin, Giampaolo, Daly, Adrian F, Hernández-Ramírez, Laura C, Araldi, Elisa, Tatsi, Christina, Dale, Ryan K, Fridell, Gus, Mittal, Arjun, Faucz, Fabio R, Iben, James R, Li, Tianwei, Vitali, Eleonora, Stojilkovic, Stanko S, Kamenicky, Peter, Villa, Chiara, Baussart, Bertrand, Chittiboina, Prashant, Toro, Camilo, Gahl, William A, Eugster, Erica A, Naves, Luciana A, Jaffrain-Rea, Marie-Lise, de Herder, Wouter W, Neggers, Sebastian Jcmm, Petrossians, Patrick, Beckers, Albert, Lania, Andrea G, Mains, Richard E, Eipper, Betty A, Stratakis, Constantine A
Published in Frontiers in endocrinology (Lausanne) (20.01.2023)
Published in Frontiers in endocrinology (Lausanne) (20.01.2023)
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First‐in‐Human (FIH), Single‐ and Multiple‐Ascending‐Dose (SAD/MAD) studies in healthy subjects of E2511, a novel tropomyosin receptor kinase a (TrkA) positive allosteric modulator (PAM)
Aceves, Pau, Hall, Nancy, Dayal, Satish, Yagi, Takuya, Chang, Julia, Mikamoto, Masaki, Ringheim, Garth E, Takesuya, Tomioka, Hiramatsu, Naoki, Gordon, Robert, Giorgi, Luigi
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
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A MULTIPLE ASCENDING-DOSE STUDY OF THE PHARMACOKINETICS AND SAFETY OF LY3154207, A CENTRALLY-ACTING DOPAMINE D1 RECEPTOR POSITIVE ALLOSTERIC MODULATOR (D1 PAM), IN HEALTHY SUBJECTS
Biglan, Kevin, Svensson, Kjell A., Wilbraham, Darren, Tsai, Max, Kielbasa, William
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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P1‐057: A MULTIPLE ASCENDING‐DOSE STUDY OF THE PHARMACOKINETICS AND SAFETY OF LY3154207, A CENTRALLY‐ACTING DOPAMINE D1 RECEPTOR POSITIVE ALLOSTERIC MODULATOR (D1 PAM), IN HEALTHY SUBJECTS
Biglan, Kevin, Svensson, Kjell A., Wilbraham, Darren, Tsai, Max, Kielbasa, William
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Typing of the Gut Microbiota Community in Japanese Subjects
Takagi, Tomohisa, Inoue, Ryo, Oshima, Akira, Sakazume, Hiroshi, Ogawa, Kenta, Tominaga, Tomo, Mihara, Yoichi, Sugaya, Takeshi, Mizushima, Katsura, Uchiyama, Kazuhiko, Itoh, Yoshito, Naito, Yuji
Published in Microorganisms (Basel) (20.03.2022)
Published in Microorganisms (Basel) (20.03.2022)
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Statistical BER Analysis of Wireline Links With Non-Binary Linear Block Codes Subject to DFE Error Propagation
Yang, Ming, Shahramian, Shayan, Shakiba, Hossein, Wong, Henry, Krotnev, Peter, Carusone, Anthony Chan
Published in IEEE transactions on circuits and systems. I, Regular papers (01.01.2020)
Published in IEEE transactions on circuits and systems. I, Regular papers (01.01.2020)
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PAM triggered visual “green-yellow-orange” ratiometric fluorescence probes in CRISPR/Cas12a: Universal detection of exosome and APE1
Liang, Zhigang, Chen, Xiang, Yu, Yan, Xu, Guanhong, Wei, Fangdi, Yang, Jing, Hu, Qin, Cen, Yao
Published in Microchemical journal (01.07.2025)
Published in Microchemical journal (01.07.2025)
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Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion
Giampaolo Trivellin, Adrian F. Daly, Laura C. Hernández-Ramírez, Elisa Araldi, Christina Tatsi, Ryan K. Dale, Gus Fridell, Arjun Mittal, Fabio R. Faucz, James R. Iben, Tianwei Li, Eleonora Vitali, Stanko S. Stojilkovic, Peter Kamenicky, Chiara Villa, Bertrand Baussart, Prashant Chittiboina, Camilo Toro, William A. Gahl, Erica A. Eugster, Luciana A. Naves, Marie-Lise Jaffrain-Rea, Wouter W. de Herder, Sebastian JCMM Neggers, Patrick Petrossians, Albert Beckers, Andrea G. Lania, Richard E. Mains, Betty A. Eipper, Constantine A. Stratakis
Published in Frontiers in Endocrinology (20.01.2023)
Published in Frontiers in Endocrinology (20.01.2023)
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Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M 4 PAM VU0467154
Gould, Robert W, Grannan, Michael D, Gunter, Barak W, Ball, Jacob, Bubser, Michael, Bridges, Thomas M, Wess, Jurgen, Wood, Michael W, Brandon, Nicholas J, Duggan, Mark E, Niswender, Colleen M, Lindsley, Craig W, Conn, P Jeffrey, Jones, Carrie K
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154
Gould, Robert W., Grannan, Michael D., Gunter, Barak W., Ball, Jacob, Bubser, Michael, Bridges, Thomas M., Wess, Jurgen, Wood, Michael W., Brandon, Nicholas J., Duggan, Mark E., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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PAM variants were associated with type 2 diabetes mellitus risk in the Chinese population
Sheng, Binwu, Wei, Huiyi, Li, Zhiying, Wei, Haoyang, Zhao, Qingbin
Published in Functional & integrative genomics (01.08.2022)
Published in Functional & integrative genomics (01.08.2022)
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PAM-altering SNP-based allele-specific CRISPR-Cas9 therapeutic strategies for Huntington’s disease
Shin, Jun Wan, Hong, Eun Pyo, Park, Seri S., Choi, Doo Eun, Zeng, Sophia, Chen, Richard Z., Lee, Jong-Min
Published in Molecular therapy. Methods & clinical development (08.09.2022)
Published in Molecular therapy. Methods & clinical development (08.09.2022)
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Adaptive Neural Compliant Force-Position Control of Serial PAM Robot
Huy Anh, Ho Pham, Son, Nguyen Ngoc, Van Kien, Cao
Published in Journal of intelligent & robotic systems (01.03.2018)
Published in Journal of intelligent & robotic systems (01.03.2018)
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The novel M4 PAM PET tracer [11C] MK‐6884: a novel biomarker for measuring target engagement of muscarinic M4 positive allosteric modulators (PAMs) as well as cholinergic tone in patients with Alzheimer’s disease
Li, Wenping, Basile, Anthony S, Tong, Ling, Van Laere, Koen, Masdeu, Joseph C., Hostetler, Eric D, Marshall, Fiona, Uslaner, Jason M.
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Institutional Review Boards and post-approval monitoring (PAM) of human research: content analysis of select university (academic health center) web pages across the USA
Cox, Shereen, Solbakk, Jan Helge, Luthardt, Frederick, Bernabe, Rosemarie DLC
Published in Current medical research and opinion (04.03.2023)
Published in Current medical research and opinion (04.03.2023)
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