Development of novel linkers to conjugate pharmacophores to a carrier antibody
Palanki, Moorthy S.S., Bhat, Abhijit, Lappe, Rodney W., Liu, Bin, Oates, Bryan, Rizzo, John, Stankovic, Nebojsa, Bradshaw, Curt
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Journal Article
Development of a long acting human growth hormone analog suitable for once a week dosing
Palanki, Moorthy S.S., Bhat, Abhijit, Bolanos, Ben, Brunel, Florence, Del Rosario, Joselyn, Dettling, Danielle, Horn, Mark, Lappe, Rodney, Preston, Ryan, Sievers, Annette, Stankovic, Nebojsa, Woodnut, Gary, Chen, Gang
Published in Bioorganic & medicinal chemistry letters (15.01.2013)
Published in Bioorganic & medicinal chemistry letters (15.01.2013)
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Journal Article
Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors
Noronha, Glenn, Barrett, Kathy, Cao, Jianguo, Dneprovskaia, Elena, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Li, G., Liao, W., Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Splittgerber, Ute, Wrasidlo, Wolfgang, Zeng, Binqi, Zhao, Ningning, Zhou, Y.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
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Journal Article
Special issue of Medicinal Chemistry Research in honor of Professor Gary L. Grunewald
Palanki, Moorthy S. S., Wolfe, Michael S., Hu, Longqin
Published in Medicinal chemistry research (01.07.2021)
Published in Medicinal chemistry research (01.07.2021)
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Journal Article
Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction
Palanki, Moorthy S. S, Dneprovskaia, Elena, Doukas, John, Fine, Richard M, Hood, John, Kang, Xinshan, Lohse, Dan, Martin, Michael, Noronha, Glenn, Soll, Richard M, Wrasidlo, Wolfgang, Yee, Shiyin, Zhu, Hong
Published in Journal of medicinal chemistry (06.09.2007)
Published in Journal of medicinal chemistry (06.09.2007)
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Journal Article
Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration
Palanki, Moorthy S. S, Akiyama, Hideo, Campochiaro, Peter, Cao, Jianguo, Chow, Chun P, Dellamary, Luis, Doukas, John, Fine, Richard, Gritzen, Colleen, Hood, John D, Hu, Steven, Kachi, Shu, Kang, Xinshan, Klebansky, Boris, Kousba, Ahmed, Lohse, Dan, Mak, Chi Ching, Martin, Michael, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Umeda, Naoyasu, Yee, Shiyin, Yokoi, Katsutoshi, Zeng, Binqi, Zhu, Hong, Noronha, Glenn
Published in Journal of medicinal chemistry (27.03.2008)
Published in Journal of medicinal chemistry (27.03.2008)
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Journal Article
Inhibitors of ABL and the ABL-T315I mutation
Noronha, Glenn, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Fine, Richard M, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andre, Palanki, Moorthy S S, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi
Published in Current topics in medicinal chemistry (01.07.2008)
Published in Current topics in medicinal chemistry (01.07.2008)
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Journal Article
Inhibition of Nuclear Factor-κB in T Cells Suppresses Lung Fibrosis
FUJIMOTO, Hajime, D'ALESSANDRO-GABAZZA, Corina N, SUMIDA, Yasuhiro, ADACHI, Yukihiko, SUZUKI, Koji, TAGUCHI, Osamu, PALANKI, Moorthy S. S, ERDMAN, Paul E, TAKAGI, Takehiro, GABAZZA, Esteban C, BRUNO, Nelson E, YANO, Yutaka, HAYASHI, Tatsuya, TAMAKI, Shigenori
Published in American journal of respiratory and critical care medicine (15.12.2007)
Published in American journal of respiratory and critical care medicine (15.12.2007)
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Journal Article
Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays
Noronha, Glenn, Barrett, Kathy, Boccia, Antonio, Brodhag, Tessa, Cao, Jianguo, Chow, Chun P., Dneprovskaia, Elena, Doukas, John, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Gu, Hong, Hanna, Ehab, Hood, John D., Hu, Steven, Kang, Xinshan, Key, Jann, Klebansky, Boris, Kousba, Ahmed, Li, Ge, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Shi, Feng, Soll, Richard, Splittgerber, Ute, Stoughton, Silva, Tang, Suhan, Yee, Shiyin, Zeng, Binqi, Zhao, Ningning, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Journal Article
The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes
Cao, Jianguo, Fine, Richard, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Noronha, Glenn, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Zeng, Binqi, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
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Journal Article
Development of novel benzotriazines for drug discovery
Palanki, Moorthy Ss, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Mak, Chi Ching, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi, Noronha, Glenn
Published in Expert opinion on drug discovery (01.01.2009)
Published in Expert opinion on drug discovery (01.01.2009)
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Journal Article
The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of In vitro and In vivo studies
Palanki, Moorthy S.S., Erdman, Paul E., Ren, Minghuan, Suto, Mark, Bennett, Brydon L., Manning, Anthony, Ransone, Lynn, Spooner, Cheryl, Desai, Sonal, Ow, Arnie, Totsuka, Ryuichi, Tsao, Peter, Toriumi, Wataru
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
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Journal Article
Structure–Activity Relationship Studies of Ethyl 2-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: An Inhibitor of AP-1 and NF-κB Mediated Gene Expression
Palanki, Moorthy S.S., Gayo-Fung, Leah M., Shevlin, Graziella I., Erdman, Paul, Sato, Mark, Goldman, Mark, Ransone, Lynn J., Spooner, Cheryl
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
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Journal Article
Solution-phase parallel synthesis using ion-exchange resins
Suto, Mark J., Gayo-Fung, Leah M., Palanki, Moorthy S.S., Sullivan, Robert
Published in Tetrahedron (16.04.1998)
Published in Tetrahedron (16.04.1998)
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Journal Article
Novel inhibitors of AP-1 and NF-κB mediated gene expression: structure–activity relationship studies of ethyl 4-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate
Palanki, Moorthy S.S, Erdman, Paul E, Manning, Anthony M, Ow, Arnold, Ransone, Lynn J, Spooner, Cheryl, Suto, Carla, Suto, Mark
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
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Journal Article
2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3‘,5‘-bis(trifluoromethyl)phenyl)- carboxamide: A Potent Inhibitor of NF-κB- and AP-1-Mediated Gene Expression Identified Using Solution-Phase Combinatorial Chemistry
Sullivan, Robert W, Bigam, Colin G, Erdman, Paul E, Palanki, Moorthy S. S, Anderson, David W, Goldman, Mark E, Ransone, Lynn J, Suto, Mark J
Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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Journal Article
Functional analogs of CC-1065 and the duocarmycins incorporating the 9a-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (C2BI) alkylation subunit: synthesis and preliminary DNA alkylation studies
Boger, Dale L, Palanki, Moorthy S. S
Published in Journal of the American Chemical Society (01.11.1992)
Published in Journal of the American Chemical Society (01.11.1992)
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Journal Article
Use of transferred nuclear overhauser effects to determine the conformation of 1-(3,4-dichlorophenyl)-2-aminopropane when bound to the active site of phenylethanolamine N-methyltransferace (PNMT)
Grunewald, Gary L., Palanki, Moorthy S.S., Velde, David Vander
Published in Bioorganic & medicinal chemistry letters (1992)
Published in Bioorganic & medicinal chemistry letters (1992)
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Journal Article
HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
AYALA, LETICIA, KOIS, ADAM, SAHASRABUDHE, KIRAM, CLAREEN, STEVEN S, DELGADO MEDEROS, MARIA MERCEDES, NADOLNY, LISA, HUGHES, KEVIN, PLANTEVIN-KRENITSKY, VERONIQUE, SLOSS, MARIANNE K, MCCARRICK, MEG, SATOH, YOSHITAKA, SAPIENZA, JOHN, SUDBECK, ELISE, ALBERS, RONALD J, HILGRAF, ROBERT, PALANKI, MOORTHY S.S, WRIGHT, JONATHAN, HEGDE, SAYEE G
Year of Publication 26.11.2013
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Year of Publication 26.11.2013
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