3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk
Su, Chun, Gao, Long, May, Catherine L, Pippin, James A, Boehm, Keith, Lee, Michelle, Liu, Chengyang, Pahl, Matthew C, Golson, Maria L, Naji, Ali, Grant, Struan F A, Wells, Andrew D, Kaestner, Klaus H
Published in Cell metabolism (06.09.2022)
Published in Cell metabolism (06.09.2022)
Get full text
Journal Article
Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types
Pahl, Matthew C, Le Coz, Carole, Su, Chun, Sharma, Prabhat, Thomas, Rajan M, Pippin, James A, Cruz Cabrera, Emylette, Johnson, Matthew E, Leonard, Michelle E, Lu, Sumei, Chesi, Alessandra, Sullivan, Kathleen E, Romberg, Neil, Grant, Struan F A, Wells, Andrew D
Published in Genome Biology (03.06.2022)
Published in Genome Biology (03.06.2022)
Get full text
Journal Article
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Thomas, Rajan M, Pahl, Matthew C, Wang, Liqing, Grant, Struan F A, Hancock, Wayne W, Wells, Andrew D
Published in eLife (24.04.2024)
Published in eLife (24.04.2024)
Get full text
Journal Article
Implicating type 2 diabetes effector genes in relevant metabolic cellular models using promoter-focused Capture-C
Wachowski, Nicholas A, Pippin, James A, Boehm, Keith, Lu, Sumei, Leonard, Michelle E, Manduchi, Elisabetta, Parlin, Ursula W, Wabitsch, Martin, Chesi, Alessandra, Wells, Andrew D, Grant, Struan F A, Pahl, Matthew C
Published in Diabetologia (06.09.2024)
Published in Diabetologia (06.09.2024)
Get full text
Journal Article
3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders
Su, Chun, Argenziano, Mariana, Lu, Sumei, Pippin, James A., Pahl, Matthew C., Leonard, Michelle E., Cousminer, Diana L., Johnson, Matthew E., Lasconi, Chiara, Wells, Andrew D., Chesi, Alessandra, Grant, Struan F.A.
Published in Progress in neurobiology (01.06.2021)
Published in Progress in neurobiology (01.06.2021)
Get full text
Journal Article
Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm
Pahl, Matthew C, Erdman, Robert, Kuivaniemi, Helena, Lillvis, John H, Elmore, James R, Tromp, Gerard
Published in International journal of molecular sciences (18.05.2015)
Published in International journal of molecular sciences (18.05.2015)
Get full text
Journal Article
Perturbation of the insomnia WDR90 genome-wide association studies locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q
Sonti, Shilpa, Littleton, Sheridan H, Pahl, Matthew C, Zimmerman, Amber J, Chesi, Alessandra, Palermo, Justin, Lasconi, Chiara, Brown, Elizabeth B, Pippin, James A, Wells, Andrew D, Doldur-Balli, Fusun, Pack, Allan I, Gehrman, Phillip R, Keene, Alex C, Grant, Struan F A
Published in Sleep (New York, N.Y.) (11.07.2024)
Published in Sleep (New York, N.Y.) (11.07.2024)
Get more information
Journal Article
Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits
Lasconi, Chiara, Pahl, Matthew C, Pippin, James A, Su, Chun, Johnson, Matthew E, Chesi, Alessandra, Boehm, Keith, Manduchi, Elisabetta, Ou, Kristy, Golson, Maria L, Wells, Andrew D, Kaestner, Klaus H, Grant, Struan F A
Published in Sleep (New York, N.Y.) (11.08.2022)
Published in Sleep (New York, N.Y.) (11.08.2022)
Get full text
Journal Article
Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
Pahl, Matthew C, Sharma, Prabhat, Thomas, Rajan M, Thompson, Zachary, Mount, Zachary, Pippin, James A, Morawski, Peter A, Sun, Peng, Su, Chun, Campbell, Daniel, Grant, Struan F A, Wells, Andrew D
Published in eLife (20.09.2024)
Published in eLife (20.09.2024)
Get full text
Journal Article
Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci
Hammond, Reza K, Pahl, Matthew C, Su, Chun, Cousminer, Diana L, Leonard, Michelle E, Lu, Sumei, Doege, Claudia A, Wagley, Yadav, Hodge, Kenyaita M, Lasconi, Chiara, Johnson, Matthew E, Pippin, James A, Hankenson, Kurt D, Leibel, Rudolph L, Chesi, Alessandra, Wells, Andrew D, Grant, Struan Fa
Published in eLife (18.01.2021)
Published in eLife (18.01.2021)
Get full text
Journal Article
247-OR: Variant-to-Gene-Mapping Analyses Reveal a Role for Pancreatic Islet Cells in Conferring Genetic Susceptibility to Sleep-Related Traits
LASCONI, CHIARA, PAHL, MATTHEW C., PIPPIN, JAMES A., SU, CHUN, JOHNSON, MATTHEW, CHESI, ALESSANDRA, WELLS, ANDREW D., KAESTNER, KLAUS H., GRANT, STRUAN F.A.
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
Get full text
Journal Article
298-OR: Variant-to-Gene Mapping at the Childhood Obesity Locus on chr12q13 and Subsequent Luciferase Assay Analyses Implicate rs71329as a Causal Variant within the 3’ UTR of FAIM2
LITTLETON, SHERIDAN H., BRADFIELD, JONATHAN, PIPPIN, JAMES A., SU, CHUN, CHESI, ALESSANDRA, WELLS, ANDREW D., BERKOWITZ, ROBERT I., PAHL, MATTHEW C., GRANT, STRUAN F.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
Get full text
Journal Article
MicroRNA expression signature in human abdominal aortic aneurysms
Pahl, Matthew C, Derr, Kimberly, Gäbel, Gabor, Hinterseher, Irene, Elmore, James R, Schworer, Charles M, Peeler, Thomas C, Franklin, David P, Gray, John L, Carey, David J, Tromp, Gerard, Kuivaniemi, Helena
Published in BMC medical genomics (15.06.2012)
Published in BMC medical genomics (15.06.2012)
Get full text
Journal Article
245-OR: CIS-Regulatory Architecture of Human ESC-Derived Hypothalamic Neuron Differentiation Aids in Variant-to-Gene Mapping of Type 2 Diabetes Related Traits
PAHL, MATTHEW C., LITTLETON, SHERIDAN H., DOEGE, CLAUDIA, HODGE, KENYAITA M., LEONARD, MICHELLE, LU, SUMEI, HAMMOND, REZA, BOEHM, KEITH, LASCONI, CHIARA, SU, CHUN, CHESI, ALESSANDRA, PIPPIN, JAMES A., JOHNSON, MATTHEW, WELLS, ANDREW D., VOIGHT, BENJAMIN F., LEIBEL, RUDOLPH, GRANT, STRUAN F., COUSMINER, DIANA L.
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
Get full text
Journal Article
Variant to gene mapping for carpal tunnel syndrome risk loci implicates skeletal muscle regulatory elements
Pahl, Matthew C., Liu, Lin, Pippin, James A., Wagley, Yadav, Boehm, Keith, Hankenson, Kurt D., Wells, Andrew D., Yang, Wenli, Grant, Struan F.A.
Published in EBioMedicine (01.03.2024)
Published in EBioMedicine (01.03.2024)
Get full text
Journal Article