High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome
Aretz, Stefan, Stienen, Dietlinde, Uhlhaas, Siegfried, Loff, Steffan, Back, Walter, Pagenstecher, Constanze, McLeod, D. Ross, Graham, Gail E., Mangold, Elisabeth, Santer, René, Propping, Peter, Friedl, Waltraut
Published in Human mutation (01.12.2005)
Published in Human mutation (01.12.2005)
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Journal Article
Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium
PLASCHKE, Jens, ENGEL, Christoph, RÜSCHOFF, Jose, LOEFFLER, Markus, SCHACKERT, Hans K, KRÜGER, Stefan, HOLINSKI-FEDER, Elke, PAGENSTECHER, Constanze, MANGOLD, Elisabeth, MOESLEIN, Gabriela, SCHULMANN, Karsten, GEBERT, Johannes, VON KNEBEL DOEBERITZ, Magnus
Published in Journal of clinical oncology (15.11.2004)
Published in Journal of clinical oncology (15.11.2004)
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Journal Article
Genotype-Phenotype Comparison of German MLH1 and MSH2 Mutation Carriers Clinically Affected With Lynch Syndrome: A Report by the German HNPCC Consortium
GOECKE, Timm, SCHULMANN, Karsten, DIETMAIER, Wolfgang, MANGOLD, Elisabeth, FRIEDRICHS, Nicolaus, PROPPING, Peter, KRÜGER, Stefan, GEBERT, Johannes, SCHMIEGEL, Wolff, RUESCHOFF, Josef, LOEFFLER, Markus, MOESLEIN, Gabriela, ENGEL, Christoph, HOLINSKI-FEDER, Eike, PAGENSTECHER, Constanze, SCHACKERT, Hans K, KLOOR, Matthias, KUNSTMANN, Erdmute, VOGELSANG, Holger, KELLER, Gisela
Published in Journal of clinical oncology (10.09.2006)
Published in Journal of clinical oncology (10.09.2006)
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Journal Article
HNPCC-associated small bowel cancer: clinical and molecular characteristics
Schulmann, Karsten, Brasch, Frank E, Kunstmann, Erdmute, Engel, Christoph, Pagenstecher, Constanze, Vogelsang, Holger, Krüger, Stefan, Vogel, Tilman, Knaebel, Hanns-Peter, Rüschoff, Josef, Hahn, Stephan A, Knebel-Doeberitz, Magnus V, Moeslein, Gabriela, Meltzer, Stephen J, Schackert, Hans K, Tympner, Christiane, Mangold, Elisabeth, Schmiegel, Wolff
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2005)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2005)
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Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants
PAGENSTECHER, Constanze, WEHNER, Maria, MANGOLD, Elisabeth, FRIEDL, Waltraut, RAHNER, Nils, ARETZ, Stefan, FRIEDRICHS, Nicolaus, SENGTELLER, Marlies, HENN, Wolfram, BUETTNER, Reinhard, PROPPING, Peter
Published in Human genetics (01.03.2006)
Published in Human genetics (01.03.2006)
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Hereditary nonpolyposis colorectal cancer: Frequent occurrence of large genomic deletions in MSH2 and MLH1 genes
Wang, Yaping, Friedl, Waltraut, Lamberti, Christof, Jungck, Matthias, Mathiak, Micaela, Pagenstecher, Constanze, Propping, Peter, Mangold, Elisabeth
Published in International journal of cancer (20.02.2003)
Published in International journal of cancer (20.02.2003)
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Journal Article
Microsatellite instability of selective target genes in HNPCC-associated colon adenomas
WOERNER, Stefan M, KLOOR, Matthias, PAGENSTECHER, Constanze, SCHACKERT, Hans K, MÖSLEIN, Gabriela, VOGELSANG, Holger, VON KNEBEL DOEBERITZ, Magnus, GEBERT, Johannes F, MUELLER, Annegret, RUESCHOFF, Josef, FRIEDRICHS, Nicolaus, BUETTNER, Reinhard, BUZELLO, Moriz, KIENLE, Peter, KNAEBEL, Hanns-Peter, KUNSTMANN, Erdmute
Published in Oncogene (07.04.2005)
Published in Oncogene (07.04.2005)
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Spectrum and frequencies of mutations inMSH2 andMLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer
Mangold, Elisabeth, Pagenstecher, Constanze, Friedl, Waltraut, Mathiak, Micaela, Buettner, Reinhard, Engel, Christoph, Loeffler, Markus, Holinski-Feder, Elke, Müller-Koch, Yvonne, Keller, Gisela, Schackert, Hans K., Krüger, Stefan, Goecke, Timm, Moeslein, Gabriela, Kloor, Matthias, Gebert, Johannes, Kunstmann, Erdmute, Schulmann, Karsten, Rüschoff, Josef, Propping, Peter
Published in International journal of cancer (20.09.2005)
Published in International journal of cancer (20.09.2005)
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MUTYH‐associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype
Aretz, Stefan, Uhlhaas, Siegfried, Goergens, Heike, Siberg, Kirsten, Vogel, Matthias, Pagenstecher, Constanze, Mangold, Elisabeth, Caspari, Reiner, Propping, Peter, Friedl, Waltraut
Published in International journal of cancer (15.08.2006)
Published in International journal of cancer (15.08.2006)
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Journal Article
Frequency and parental origin of de novo APC mutations in familial adenomatous polyposis
ARETZ, Stefan, UHLHAAS, Siegfried, CASPARI, Reiner, MANGOLD, Elisabeth, PAGENSTECHER, Constanze, PROPPING, Peter, FRIEDL, Waltraut
Published in European journal of human genetics : EJHG (01.01.2004)
Published in European journal of human genetics : EJHG (01.01.2004)
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Journal Article
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer
Mangold, Elisabeth, Pagenstecher, Constanze, Friedl, Waltraut, Mathiak, Micaela, Buettner, Reinhard, Engel, Christoph, Loeffler, Markus, Holinski‐Feder, Elke, Müller‐Koch, Yvonne, Keller, Gisela, Schackert, Hans K., Krüger, Stefan, Goecke, Timm, Moeslein, Gabriela, Kloor, Matthias, Gebert, Johannes, Kunstmann, Erdmute, Schulmann, Karsten, Rüschoff, Josef, Propping, Peter
Published in International journal of cancer (20.09.2005)
Published in International journal of cancer (20.09.2005)
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Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining
Mangold, Elisabeth, Pagenstecher, Constanze, Friedl, Waltraut, Fischer, Hans-Peter, Merkelbach-Bruse, Sabine, Ohlendorf, Maike, Friedrichs, Nicolaus, Aretz, Stefan, Buettner, Reinhard, Propping, Peter, Mathiak, Micaela
Published in The Journal of pathology (01.12.2005)
Published in The Journal of pathology (01.12.2005)
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Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer
Engel, Christoph, Forberg, Jochen, Holinski‐Feder, Elke, Pagenstecher, Constanze, Plaschke, Jens, Kloor, Matthias, Poremba, Christopher, Pox, Christian P., Rüschoff, Josef, Keller, Gisela, Dietmaier, Wolfgang, Rümmele, Petra, Friedrichs, Nicolaus, Mangold, Elisabeth, Buettner, Reinhard, Schackert, Hans K., Kienle, Peter, Stemmler, Susanne, Moeslein, Gabriela, Loeffler, Markus
Published in International journal of cancer (01.01.2006)
Published in International journal of cancer (01.01.2006)
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Journal Article
Familial adenomatous polyposis: Aberrant splicing due to missense or silent mutations in the APC gene
Aretz, Stefan, Uhlhaas, Siegfried, Sun, Yuli, Pagenstecher, Constanze, Mangold, Elisabeth, Caspari, Reiner, Möslein, Gabriela, Schulmann, Karsten, Propping, Peter, Friedl, Waltraut
Published in Human mutation (01.11.2004)
Published in Human mutation (01.11.2004)
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Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study
Krüger, Stefan, Silber, Ann-Sophie, Engel, Christoph, Görgens, Heike, Mangold, Elisabeth, Pagenstecher, Constanze, Holinski-Feder, Elke, von Knebel Doeberitz, Magnus, Moeslein, Gabriela, Dietmaier, Wolfgang, Stemmler, Susanne, Friedl, Waltraut, Rüschoff, Josef, Schackert, Hans K
Published in The lancet oncology (01.08.2005)
Published in The lancet oncology (01.08.2005)
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Journal Article
The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1
Krüger, Stefan, Engel, Christoph, Bier, Andrea, Silber, Ann-Sophie, Görgens, Heike, Mangold, Elisabeth, Pagenstecher, Constanze, Holinski-Feder, Elke, von Knebel Doeberitz, Magnus, Royer-Pokora, Brigitte, Dechant, Stefan, Pox, Christian, Rahner, Nils, Müller, Annegret, Schackert, Hans K
Published in Cancer letters (08.07.2007)
Published in Cancer letters (08.07.2007)
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Journal Article
Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects
Gottschling, Sven, Reinhard, Harald, Pagenstecher, Constanze, Krüger, Stefan, Raedle, Jochen, Plotz, Guido, Henn, Wolfram, Buettner, Reinhard, Meyer, Sascha, Graf, Norbert
Published in European journal of pediatrics (01.02.2008)
Published in European journal of pediatrics (01.02.2008)
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Journal Article
Hereditary nonpolyposis colorectal cancer : pitfalls in deletion screening in MSH2 and MLH1 genes
WEHNER, Maria, MANGOLD, Elisabeth, SENGTELLER, Marlies, FRIEDRICHS, Nicolaus, ARETZ, Stefan, FRIEDL, Waltraut, PROPPING, Peter, PAGENSTECHER, Constanze
Published in European journal of human genetics : EJHG (01.08.2005)
Published in European journal of human genetics : EJHG (01.08.2005)
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Journal Article
Absence of association between cyclin D1 ( CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer
Krüger, Stefan, Engel, Christoph, Bier, Andrea, Mangold, Elisabeth, Pagenstecher, Constanze, von Knebel Doeberitz, Magnus, Holinski-Feder, Elke, Moeslein, Gabriela, Keller, Gisela, Kunstmann, Erdmute, Friedl, Waltraut, Plaschke, Jens, Rüschoff, Josef, Schackert, Hans K., The German HNPCC-Consortium
Published in Cancer letters (18.05.2006)
Published in Cancer letters (18.05.2006)
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Journal Article
Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue
Plaschke, Jens, Krüger, Stefan, Dietmaier, Wolfgang, Gebert, Johannes, Sutter, Christian, Mangold, Elisabeth, Pagenstecher, Constanze, Holinski-Feder, Elke, Schulmann, Karsten, Möslein, Gabriela, Rüschoff, Josef, Engel, Christoph, Evans, Gareth, Schackert, Hans K.
Published in Human mutation (01.03.2004)
Published in Human mutation (01.03.2004)
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