MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer
Hitchins, Megan, Williams, Rachel, Cheong, Kayfong, Halani, Nimita, Lin, Vita A P, Packham, Deborah, Ku, Sue, Buckle, Andrew, Hawkins, Nicholas, Burn, John, Gallinger, Steven, Goldblatt, Jack, Kirk, Judy, Tomlinson, Ian, Scott, Rodney, Spigelman, Allan, Suter, Catherine, Martin, David, Suthers, Graeme, Ward, Robyn
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2005)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2005)
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Journal Article
Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer
Sloane, Mathew A, Nunez, Andrea C, Packham, Deborah, Kwok, Chau-To, Suthers, Graeme, Hesson, Luke B, Ward, Robyn L
Published in JAMA oncology (01.10.2015)
Published in JAMA oncology (01.10.2015)
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Journal Article
Pathogenic germline MCM9 variants are rare in Australian lynch-like syndrome patients
Liu, Qing, Hesson, Luke B, Nunez, Andrea C, Packham, Deborah, Hawkins, Nicholas J, Ward, Robyn L, Sloane, Mathew A
Published in Cancer genetics (01.11.2016)
Published in Cancer genetics (01.11.2016)
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Journal Article
A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines
Hesson, Luke B, Packham, Deborah, Pontzer, Emily, Funchain, Pauline, Eng, Charis, Ward, Robyn L
Published in Biological procedures online (10.04.2012)
Published in Biological procedures online (10.04.2012)
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Journal Article
Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers
Packham, Deborah, Ward, Robyn L, Ap Lin, Vita, Hawkins, Nicholas J, Hitchins, Megan P
Published in Diagnostic molecular pathology (01.06.2009)
Published in Diagnostic molecular pathology (01.06.2009)
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Journal Article
A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome
Liu, Qing, Hesson, Luke B, Nunez, Andrea C, Packham, Deborah, Williams, Rachel, Ward, Robyn L, Sloane, Mathew A
Published in Carcinogenesis (New York) (01.01.2016)
Published in Carcinogenesis (New York) (01.01.2016)
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Journal Article
Disruption of a −35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells
Liu, Qing, Thoms, Julie A.I., Nunez, Andrea C., Huang, Yizhou, Knezevic, Kathy, Packham, Deborah, Poulos, Rebecca C., Williams, Rachel, Beck, Dominik, Hawkins, Nicholas J., Ward, Robyn L., Wong, Jason W.H., Hesson, Luke B., Sloane, Mathew A., Pimanda, John E.
Published in Clinical cancer research (15.09.2018)
Published in Clinical cancer research (15.09.2018)
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Journal Article
Disruption of a -35kb enhancer impairs CTCF binding and MLH1 expression in colorectal cells
Liu, Qing, Thoms, Julie A, Nunez, Andrea C, Huang, Yizhou, Knezevic, Kathy, Packham, Deborah, Poulos, Rebecca C, Williams, Rachel, Beck, Dominik, Hawkins, Nicholas J, Ward, Robyn L, Wong, Jason W H, Hesson, Luke B, Sloane, Mathew A, Pimanda, John
Published in Clinical cancer research (13.06.2018)
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Published in Clinical cancer research (13.06.2018)
Journal Article
Phase I Clinical Trial of the Chimeric Monoclonal Antibody (c30.6) in Patients with Metastatic Colorectal Cancer
WARD, Robyn L, PACKHAM, Deborah, PRABAKARAN, Krishnan, FREUND, Judy, FULLHAM, Michael, RULE, Michele, DALLEY, David, MEAGHER, Alan, HAWKINS, Nicholas J, SMITH, Glenn M, SMYTHE, Anne M, MURRAY, Jayne, ANDERSON-STEWART, Peter, KITCHEN, Neil, MUIRHEAD, Rosyln, PHILLIPS, Peter, GRAY, Peter, BIGG-WITHER, Grant
Published in Clinical cancer research (01.12.2000)
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Published in Clinical cancer research (01.12.2000)
Journal Article
De novo constitutional MLH1 epimutations confer early‐onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one
Goel, Ajay, Nguyen, Thuy‐Phuong, Leung, Hon‐Chiu E., Nagasaka, Takeshi, Rhees, Jennifer, Hotchkiss, Erin, Arnold, Mildred, Banerji, Pia, Koi, Minoru, Kwok, Chau‐To, Packham, Deborah, Lipton, Lara, Boland, C. Richard, Ward, Robyn L., Hitchins, Megan P.
Published in International journal of cancer (15.02.2011)
Published in International journal of cancer (15.02.2011)
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Journal Article
Lynch Syndrome Associated with Two MLH1 Promoter Variants and Allelic Imbalance of MLH1 Expression
Hesson, Luke B., Packham, Deborah, Kwok, Chau-To, Nunez, Andrea C., Ng, Benedict, Schmidt, Christa, Fields, Michael, Wong, Jason W.H., Sloane, Mathew A., Ward, Robyn L.
Published in Human mutation (01.06.2015)
Published in Human mutation (01.06.2015)
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Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors
Hesson, Luke B, Ng, Benedict, Zarzour, Peter, Srivastava, Sameer, Kwok, Chau-To, Packham, Deborah, Nunez, Andrea C, Beck, Dominik, Ryan, Regina, Dower, Ashraf, Ford, Caroline E, Pimanda, John E, Sloane, Mathew A, Hawkins, Nicholas J, Bourke, Michael J, Wong, Jason W H, Ward, Robyn L
Published in Molecular cancer research (01.12.2016)
Published in Molecular cancer research (01.12.2016)
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Journal Article
Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr
Thoms, Julie A. I., Knezevic, Kathy, Liu, Jia Jenny, Glaros, Elias N., Thai, Thuan, Qiao, Qiao, Campbell, Heather, Packham, Deborah, Huang, Yizhou, Papathanasiou, Peter, Tunningley, Robert, Whittle, Belinda, Yeung, Amanda W. S., Chandrakanthan, Vashe, Hesson, Luke, Chen, Vivien, Wong, Jason W. H., Purton, Louise E., Ward, Robyn L., Thomas, Shane R., Pimanda, John E.
Published in Molecular and cellular biology (01.04.2016)
Published in Molecular and cellular biology (01.04.2016)
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Journal Article
Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer
HITCHINS, Megan P, VITA AP LIN, STIRZAKER, Clare, CLARK, Susan, HAWKING, Nicholas J, WARD, Robyn L, BUCKLE, Andrew, CHEONG, Kayfong, HALANI, Nimita, SU KU, KWOK, Chau-To, PACKHAM, Deborah, SUTER, Catherine M, MEAGHER, Alan
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Published in Cancer research (Chicago, Ill.) (01.10.2007)
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Journal Article
Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing
Poulos, Rebecca C, Perera, Dilmi, Packham, Deborah, Shah, Anushi, Janitz, Caroline, Pimanda, John E, Hawkins, Nicholas, Ward, Robyn L, Hesson, Luke B, Wong, Jason W H
Published in JNCI cancer spectrum (01.06.2019)
Published in JNCI cancer spectrum (01.06.2019)
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Journal Article
Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified
Ward, Robyn Lynne, Turner, Jenny, Williams, Rachel, Pekarsky, Brita, Packham, Deborah, Velickovic, Marija, Meagher, Alan, O'Connor, Terence, Hawkins, Nicholas John
Published in The Journal of pathology (01.12.2005)
Published in The Journal of pathology (01.12.2005)
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Journal Article
In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer
Poulos, Rebecca C, Perera, Dilmi, Packham, Deborah, Shah, Anushi, Janitz, Caroline, Pimanda, John E, Hawkins, Nicholas, Ward, Robyn L, Hesson, Luke B, Wong, Jason Wh
Published in bioRxiv (16.01.2018)
Published in bioRxiv (16.01.2018)
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