Identification of 2‑(4-(Phenylsulfonyl)piperazine-1-yl)pyrimidine Analogues as Novel Inhibitors of Chikungunya Virus
Moesslacher, Julia, Battisti, Verena, Delang, Leen, Neyts, Johan, Abdelnabi, Rana, Pürstinger, Gerhard, Urban, Ernst, Langer, Thierry
Published in ACS medicinal chemistry letters (14.05.2020)
Published in ACS medicinal chemistry letters (14.05.2020)
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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family
van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M, Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D, Arnold, Jamie J, Cameron, Craig E, Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J M
Published in PLoS pathogens (01.03.2015)
Published in PLoS pathogens (01.03.2015)
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Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase
Musiu, Simone, Castillo, Yunierkis Perez, Muigg, Alexandra, Pürstinger, Gerhard, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan
Published in Molecules (Basel, Switzerland) (12.03.2020)
Published in Molecules (Basel, Switzerland) (12.03.2020)
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The Thiazolobenzimidazole TBZE-029 Inhibits Enterovirus Replication by Targeting a Short Region Immediately Downstream from Motif C in the Nonstructural Protein 2C
De Palma, Armando M, Heggermont, Ward, Lanke, Kjerstin, Coutard, Bruno, Bergmann, Mirko, Monforte, Anna-Maria, Canard, Bruno, De Clercq, Erik, Chimirri, Alba, Pürstinger, Gerhard, Rohayem, Jacques, van Kuppeveld, Frank, Neyts, Johan
Published in Journal of Virology (01.05.2008)
Published in Journal of Virology (01.05.2008)
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Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase
Shih, I-Hung, Vliegen, Inge, Peng, Betty, Yang, Huiling, Hebner, Christy, Paeshuyse, Jan, Pürstinger, Gerhard, Fenaux, Martijn, Tian, Yang, Mabery, Eric, Qi, Xiaoping, Bahador, Gina, Paulson, Matthew, Lehman, Laura S, Bondy, Steven, Tse, Winston, Reiser, Hans, Lee, William A, Schmitz, Uli, Neyts, Johan, Zhong, Weidong
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
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Potential use of antiviral agents in polio eradication
De Palma, Armando M, Pürstinger, Gerhard, Wimmer, Eva, Patick, Amy K, Andries, Koen, Rombaut, Bart, De Clercq, Erik, Neyts, Johan
Published in Emerging infectious diseases (01.04.2008)
Published in Emerging infectious diseases (01.04.2008)
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Anti-enteroviral triple combination of viral replication inhibitors: activity against coxsackievirus B1 neuroinfection in mice
Stoyanova, Adelina, Nikolova, Ivanka, Pürstinger, Gerhard, Dobrikov, Georgi, Dimitrov, Vladimir, Philipov, Stefan, Galabov, Angel S
Published in Antiviral chemistry & chemotherapy (01.12.2015)
Published in Antiviral chemistry & chemotherapy (01.12.2015)
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Synthesis, Structure−Activity Relationships, and Antitumor Studies of 2-Benzoxazolyl Hydrazones Derived from Alpha-(N)-acyl Heteroaromatics
Easmon, Johnny, Pürstinger, Gerhard, Thies, Katrin-Sofia, Heinisch, Gottfried, Hofmann, Johann
Published in Journal of medicinal chemistry (19.10.2006)
Published in Journal of medicinal chemistry (19.10.2006)
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Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication
van der Schaar, Hilde M, van der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, de Vries, Erik, de Haan, Cornelis A M, Neyts, Johan, van Kuppeveld, Frank J M
Published in Cell research (01.11.2012)
Published in Cell research (01.11.2012)
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Synthesis, Cytotoxicity, and Antitumor Activity of Copper(II) and Iron(II) Complexes of 4N-Azabicyclo[3.2.2]nonane Thiosemicarbazones Derived from Acyl Diazines
EASMON, Johnny, PüRSTINGER, Gerhard, HEINISCH, Gottfried, ROTH, Thomas, FIEBIG, Heinz H., HOLZER, Wolfgang, JäGER, Walter, JENNY, Marcel, HOFMANN, Johann
Published in Journal of medicinal chemistry (21.06.2001)
Published in Journal of medicinal chemistry (21.06.2001)
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Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors
Kovacikova, Kristina, Gorostiola González, Marina, Jones, Rhian, Reguera, Juan, Gigante, Alba, Pérez-Pérez, María-Jesús, Pürstinger, Gerhard, Moesslacher, Julia, Langer, Thierry, Jeong, Lak Shin, Delang, Leen, Neyts, Johan, Snijder, Eric J, van Westen, Gerard J P, van Hemert, Martijn J
Published in Antimicrobial agents and chemotherapy (17.06.2021)
Published in Antimicrobial agents and chemotherapy (17.06.2021)
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Substituted 2,6-bis(benzimidazol-2-yl)pyridines: A novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase
Musiu, Simone, Pürstinger, Gerhard, Stallinger, Sylvia, Vrancken, Robert, Haegeman, Andy, Koenen, Frank, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan
Published in Antiviral research (01.06.2014)
Published in Antiviral research (01.06.2014)
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Substituted imidazopyridines as potent inhibitors of HCV replication
Vliegen, Inge, Paeshuyse, Jan, De Burghgraeve, Tine, Lehman, Laura S, Paulson, Matthew, Shih, I-Hung, Mabery, Eric, Boddeker, Nina, De Clercq, Erik, Reiser, Hans, Oare, David, Lee, William A, Zhong, Weidong, Bondy, Steven, Pürstinger, Gerhard, Neyts, Johan
Published in Journal of hepatology (01.05.2009)
Published in Journal of hepatology (01.05.2009)
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H1PVAT is a novel and potent early-stage inhibitor of poliovirus replication that targets VP1
TIJSMA, Aloys, THIBAUT, Hendrik Jan, MARCHAND, Arnaud, CHALTIN, Patrick, NEYTS, Johan, LEYSSEN, Pieter, SPIESER, Stéphane A. H, DE PALMA, Armando, KOUKNI, Mohamed, RHODEN, Eric, OBERSTE, Steve, PÜRSTINGER, Gerhard, VOLNY-LURAGHI, Antonia, MARTIN, Javier
Published in Antiviral research (01.10.2014)
Published in Antiviral research (01.10.2014)
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The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family
van Der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, de Palma, Armando M., Tanchis, Federica, Goris, Nesya, Lefebvre, David, de Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D., Arnold, Jamie J., Cameron, Craig E., Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J. M
Published in PLoS pathogens (01.03.2015)
Published in PLoS pathogens (01.03.2015)
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The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family: e1004733
Linden, Lonneke vander, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, Palma, Armando MDe, Tanchis, Federica, Goris, Nesya, Lefebvre, David, Clercq, Kris De, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D, Arnold, Jamie J, Cameron, Craig E, Verdaguer, Nuria, Neyts, Johan, Kuppeveld, J Mvan
Published in PLoS pathogens (01.03.2015)
Published in PLoS pathogens (01.03.2015)
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