Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives
Ozaki, Ema, Campbell, Matthew, Doyle, Sarah L
Published in Journal of inflammation research (01.01.2015)
Published in Journal of inflammation research (01.01.2015)
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Journal Article
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O'Neill, Luke A J, Hollyfield, Joe G, Humphries, Peter
Published in Nature medicine (01.05.2012)
Published in Nature medicine (01.05.2012)
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Journal Article
IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
Augustine, Josy, Pavlou, Sofia, Ali, Imran, Harkin, Kevin, Ozaki, Ema, Campbell, Matthew, Stitt, Alan W, Xu, Heping, Chen, Mei
Published in Journal of neuroinflammation (03.12.2019)
Published in Journal of neuroinflammation (03.12.2019)
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Journal Article
Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration
Mulfaul, Kelly, Ozaki, Ema, Fernando, Nilisha, Brennan, Kiva, Chirco, Kathleen R., Connolly, Emma, Greene, Chris, Maminishkis, Arvydas, Salomon, Robert G., Linetsky, Mikhail, Natoli, Riccardo, Mullins, Robert F., Campbell, Matthew, Doyle, Sarah L.
Published in Cell reports (Cambridge) (18.02.2020)
Published in Cell reports (Cambridge) (18.02.2020)
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Journal Article
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration
Doyle, Sarah L, Ozaki, Ema, Brennan, Kiva, Humphries, Marian M, Mulfaul, Kelly, Keaney, James, Kenna, Paul F, Maminishkis, Arvydas, Kiang, Anna-Sophia, Saunders, Sean P, Hams, Emily, Lavelle, Ed C, Gardiner, Clair, Fallon, Padraic G, Adamson, Peter, Humphries, Peter, Campbell, Matthew
Published in Science translational medicine (02.04.2014)
Published in Science translational medicine (02.04.2014)
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Journal Article
SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration
Gibbons, Luke, Ozaki, Ema, Greene, Chris, Trappe, Anne, Carty, Michael, Coppinger, Judith A, Bowie, Andrew G, Campbell, Matthew, Doyle, Sarah L
Published in Frontiers in neuroscience (01.04.2022)
Published in Frontiers in neuroscience (01.04.2022)
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Journal Article
Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury
Campbell, Matthew, Hanrahan, Finnian, Gobbo, Oliviero L, Kelly, Michael E, Kiang, Anna-Sophia, Humphries, Marian M, Nguyen, Anh T H, Ozaki, Ema, Keaney, James, Blau, Christoph W, Kerskens, Christian M, Cahalan, Stephen D, Callanan, John J, Wallace, Eugene, Grant, Gerald A, Doherty, Colin P, Humphries, Peter
Published in Nature communications (22.05.2012)
Published in Nature communications (22.05.2012)
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Journal Article
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration
Ozaki, Ema, Gibbons, Luke, Neto, Nuno Gb, Kenna, Paul, Carty, Michael, Humphries, Marian, Humphries, Pete, Campbell, Matthew, Monaghan, Michael, Bowie, Andrew, Doyle, Sarah L
Published in Life science alliance (01.05.2020)
Published in Life science alliance (01.05.2020)
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Journal Article
IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates
Doyle, Sarah L, López, Francisco J, Celkova, Lucia, Brennan, Kiva, Mulfaul, Kelly, Ozaki, Ema, Kenna, Paul F, Kurali, Edit, Hudson, Natalie, Doggett, Teresa, Ferguson, Thomas A, Humphries, Peter, Adamson, Peter, Campbell, Matthew
Published in Investigative ophthalmology & visual science (01.08.2015)
Published in Investigative ophthalmology & visual science (01.08.2015)
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Journal Article
Type 1 IFN Induction by Cytosolic Nucleic Acid Is Intact in Neonatal Mononuclear Cells, Contrasting Starkly with Neonatal Hyporesponsiveness to TLR Ligation Due to Independence from Endosome-Mediated IRF3 Activation
Brennan, Kiva, O'Leary, Bobby D, Mc Laughlin, Danielle, Breen, Eamon P, Connolly, Emma, Ali, Nusrat, O'Driscoll, David N, Ozaki, Ema, Mahony, Rebecca, Mulfaul, Kelly, Ryan, Aoife M, Ni Chianain, Aine, McHugh, Alison, Molloy, Eleanor J, Hogan, Andrew E, Paran, Sri, McAuliffe, Fionnuala M, Doyle, Sarah L
Published in The Journal of immunology (1950) (15.08.2018)
Published in The Journal of immunology (1950) (15.08.2018)
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Journal Article
Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease
Millar, Joshua, Ozaki, Ema, Campbell, Susan, Duckett, Catherine, Doyle, Sarah, Cole, Laura M
Published in Metabolites (09.12.2022)
Published in Metabolites (09.12.2022)
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Journal Article
Properties and Therapeutic Implications of an Enigmatic D477G RPE65 Variant Associated with Autosomal Dominant Retinitis Pigmentosa
Kiang, Anna-Sophia, Kenna, Paul F, Humphries, Marian M, Ozaki, Ema, Koenekoop, Robert K, Campbell, Matthew, Farrar, G Jane, Humphries, Pete
Published in Genes (27.11.2020)
Published in Genes (27.11.2020)
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Journal Article
Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy
Kenna, Paul F, Humphries, Marian M, Kiang, Anna-Sophia, Brabet, Philippe, Guillou, Laurent, Ozaki, Ema, Campbell, Matthew, Farrar, G Jane, Koenekoop, Robert, Humphries, Pete
Published in BMJ open ophthalmology (05.05.2020)
Published in BMJ open ophthalmology (05.05.2020)
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Journal Article
Systemic low‐molecular weight drug delivery to pre‐selected neuronal regions
Campbell, Matthew, Humphries, Marian M., Kiang, Anna‐Sophia, Nguyen, Anh T. H., Gobbo, Oliviero L., Tam, Lawrence C. S., Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G.‐Jane, Kenna, Paul F., Humphries, Peter
Published in EMBO molecular medicine (01.04.2011)
Published in EMBO molecular medicine (01.04.2011)
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Journal Article
Minocycline suppresses disease-associated microglia (DAM) in a model of photoreceptor cell degeneration
Ozaki, Ema, Delaney, Conor, Campbell, Matthew, Doyle, Sarah L.
Published in Experimental eye research (01.04.2022)
Published in Experimental eye research (01.04.2022)
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Journal Article
Interleukin‐33 regulates tissue remodelling and inhibits angiogenesis in the eye
Theodoropoulou, Sofia, Copland, David A, Liu, Jian, Wu, Jiahui, Gardner, Peter J, Ozaki, Ema, Doyle, Sarah L, Campbell, Matthew, Dick, Andrew D
Published in The Journal of pathology (01.01.2017)
Published in The Journal of pathology (01.01.2017)
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Journal Article
Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor
Yuan, Hsiangkuo, Wilson, Christy M, Xia, Jun, Doyle, Sarah L, Li, Shuqin, Fales, Andrew M, Liu, Yang, Ozaki, Ema, Mulfaul, Kelly, Hanna, Gabi, Palmer, Gregory M, Wang, Lihong V, Grant, Gerald A, Vo-Dinh, Tuan
Published in Nanoscale (21.04.2014)
Published in Nanoscale (21.04.2014)
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Journal Article
Systemic delivery of therapeutics to neuronal tissues: a barrier modulation approach
Campbell, Matthew, Ozaki, Ema, Humphries, Peter
Published in Expert opinion on drug delivery (01.07.2010)
Published in Expert opinion on drug delivery (01.07.2010)
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Journal Article
Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy
Hudson, Natalie, Celkova, Lucia, Hopkins, Alan, Greene, Chris, Storti, Federica, Ozaki, Ema, Fahey, Erin, Theodoropoulou, Sofia, Kenna, Paul F, Humphries, Marian M, Curtis, Annie M, Demmons, Eleanor, Browne, Akeem, Liddie, Shervin, Lawrence, Matthew S, Grimm, Christian, Cahill, Mark T, Humphries, Pete, Doyle, Sarah L, Campbell, Matthew
Published in JCI insight (08.08.2019)
Published in JCI insight (08.08.2019)
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