The effect of a thiazolidinedione drug, troglitazone, on glycemia in patients with type 2 diabetes mellitus poorly controlled with sulfonylurea and metformin. A multicenter, randomized, double-blind, placebo-controlled trial
Yale, J F, Valiquett, T R, Ghazzi, M N, Owens-Grillo, J K, Whitcomb, R W, Foyt, H L
Published in Annals of internal medicine (01.05.2001)
Published in Annals of internal medicine (01.05.2001)
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Journal Article
Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex
M J Czar, J K Owens-Grillo, K D Dittmar, K A Hutchison, A M Zacharek, K L Leach, M R Deibel, Jr, W B Pratt
Published in The Journal of biological chemistry (15.04.1994)
Published in The Journal of biological chemistry (15.04.1994)
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Journal Article
The native v-Raf.hsp90.p50 heterocomplex contains a novel immunophilin of the FK506 binding class
L F Stancato, Y H Chow, J K Owens-Grillo, A W Yem, M R Deibel, Jr, R Jove, W B Pratt
Published in The Journal of biological chemistry (02.09.1994)
Published in The Journal of biological chemistry (02.09.1994)
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Journal Article
The hsp90-binding Antibiotic Geldanamycin Decreases Raf Levels and Epidermal Growth Factor Signaling without Disrupting Formation of Signaling Complexes or Reducing the Specific Enzymatic Activity of Raf Kinase
Stancato, Louis F., Silverstein, Adam M., Owens-Grillo, Janet K., Chow, Yu-Hua, Jove, Richard, Pratt, William B.
Published in The Journal of biological chemistry (14.02.1997)
Published in The Journal of biological chemistry (14.02.1997)
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Journal Article
A Model of Protein Targeting Mediated by Immunophilins and Other Proteins That Bind to hsp90 via Tetratricopeptide Repeat Domains
Owens-Grillo, Janet K., Czar, Michael J., Hutchison, Kevin A., Hoffmann, Kai, Perdew, Gary H., Pratt, William B.
Published in The Journal of biological chemistry (07.06.1996)
Published in The Journal of biological chemistry (07.06.1996)
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The Cyclosporin A-binding Immunophilin CyP-40 and the FK506-binding Immunophilin hsp56 Bind to a Common Site on hsp90 and Exist in Independent Cytosolic Heterocomplexes with the Untransformed Glucocorticoid Receptor (∗)
Owens-Grillo, Janet K., Hoffmann, Kai, Hutchison, Kevin A., Yem, Anthony W., Deibel, Martin R., Handschumacher, Robert E., Pratt, William B.
Published in The Journal of biological chemistry (01.09.1995)
Published in The Journal of biological chemistry (01.09.1995)
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Journal Article
Binding of Immunophilins to the 90 kDa Heat Shock Protein (hsp90) via a Tetratricopeptide Repeat Domain Is a Conserved Protein Interaction in Plants
Owens-Grillo, Janet K, Stancato, Louis F, Hoffmann, Kai, Pratt, William B, Krishna, Priti
Published in Biochemistry (Easton) (03.12.1996)
Published in Biochemistry (Easton) (03.12.1996)
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The 23-kDa Acidic Protein in Reticulocyte Lysate Is the Weakly Bound Component of the hsp Foldosome That Is Required for Assembly of the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90 (∗)
Hutchison, Kevin A., Stancato, Louis F., Owens-Grillo, Janet K., Johnson, Jill L., Krishna, Priti, Toft, David O., Pratt, William B.
Published in The Journal of biological chemistry (11.08.1995)
Published in The Journal of biological chemistry (11.08.1995)
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The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor
Czar, M J, Owens-Grillo, J K, Yem, A W, Leach, K L, Deibel, Jr, M R, Welsh, M J, Pratt, W B
Published in Molecular endocrinology (Baltimore, Md.) (01.12.1994)
Published in Molecular endocrinology (Baltimore, Md.) (01.12.1994)
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Journal Article
The native v-Raf/hsp90/p50 heterocomplex contains a novel immunophilin of the FK506 binding class
Stancato, L F, Chow, Yu-Hua, Owens-Grillo, J K, Yem, A W, Deibel, Jr, Jove, R, Pratt, W B
Published in The Journal of biological chemistry (02.09.1994)
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Published in The Journal of biological chemistry (02.09.1994)
Journal Article
Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin
Silverstein, A M, Galigniana, M D, Chen, M S, Owens-Grillo, J K, Chinkers, M, Pratt, W B
Published in The Journal of biological chemistry (27.06.1997)
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Published in The Journal of biological chemistry (27.06.1997)
Journal Article
The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor
Czar, M J, Owens-Grillo, J K, Yem, A W, Leach, K L, Deibel, M R, Welsh, M J, Pratt, W B
Published in Molecular endocrinology (Baltimore, Md.) (01.12.1994)
Published in Molecular endocrinology (Baltimore, Md.) (01.12.1994)
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Journal Article