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Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trialResearch in context

by Man K. Chan, Mark Cotton, Adeodata R. Kekitiinwa, Elizabeth Kaudha, Suparat Kanjanavanit, Luis Prieto Tato, Deborah Ford, Carlo Giaquinto, Abdel Babiker, Jose Tomas Ramos Amador, Y. Riault, C. Kouakam, M. Ndiaye, L. Meyer, C. Cagnot, M. Chan, D. Ford, L. Harper, A. Bamford, L. Gao, A. Nunn, G. Jourdain, C. Saenjum, K. Than-in-at, N. Krueduangkam, T. Noguera, M.A. Muñoz Fernández, E. Vicentini, M. Gatto, E. Paredes, N. Chereau, L. Flet, A. Rodallec, P. Mespoulhe, N. Pavia-Ruz, J. Tuna, A. Padrao, A.C. Mendes, A.C. Matos, C. Faria, T. Silva Milhiero, M. Nyati, M. Khunene, U. Singh, A. Mamiane, T. Daniel, M. Groenewald, G. Slade, J. Coetzee, L. Ganger, S. Pieterse, S. Barnabas, M. Smuts, C. Epalza, C. Estepa, E. Sans, P. Mendez García, A. Murciano Cabeza, M. Coto, A. Mur, J.T. Ramos Amador, G. Dollenmaier, J. Boni, C. Saegesser, W. Chamjamrat, T. Thapwai, C. Ruklao, P. Ounchanum, S. Khusuwan, S. Denjanta, W. Srisuk, S. Kanjanavanit, C. Saewtrakool, D. Chutima, S. Srirojana, D. Donngernl, A. Kamkoonmongkol, P. Phunkhum, A. Nalugo, L. Kiyimba, L. Nakandi, N. Nabukeera Barung, E. Mujyambere, R. Mbabazi, J. Mwebaza, S. Oruk, M. Nannungi, D. Odoch, E. Rubanga, E.L. Babu, C. Inyakuwal, A. Uyungrwoth, I. Raus, O. Mostovenko, N. Primak, D. Nayagam, C. Gilmour, A. Adebayo, J. Daglish, L. Thrasyvoulou
Published in EClinicalMedicine (01.06.2023)
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