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Published in Molecules (Basel, Switzerland) (25.04.2019)
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Diversity-oriented synthesis encoded by deoxyoligonucleotides
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Published in Nature communications (15.08.2023)
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Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides
Hudson, Liam, Mason, Jeremy W., Westphal, Matthias V., Richter, Matthieu J. R., Thielman, Jonathan R., Hua, Bruce K., Gerry, Christopher J., Xia, Guoqin, Osswald, Heather L., Knapp, John M., Tan, Zher Yin, Kokkonda, Praveen, Tresco, Ben I. C., Liu, Shuang, Reidenbach, Andrew G., Lim, Katherine S., Poirier, Jennifer, Capece, John, Bonazzi, Simone, Gampe, Christian M., Smith, Nichola J., Bradner, James E., Coley, Connor W., Clemons, Paul A., Melillo, Bruno, Hon, C. Suk-Yee, Ottl, Johannes, Dumelin, Christoph E., Schaefer, Jonas V., Faust, Ann Marie E., Berst, Frédéric, Schreiber, Stuart L., Zécri, Frédéric J., Briner, Karin
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Published in Nature communications (21.11.2023)
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Published in PloS one (10.01.2017)
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Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR
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Published in Nature chemical biology (01.08.2007)
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Large Scale Meta-Analysis of Fragment-Based Screening Campaigns: Privileged Fragments and Complementary Technologies
Kutchukian, Peter S., Wassermann, Anne Mai, Lindvall, Mika K., Wright, S. Kirk, Ottl, Johannes, Jacob, Jaison, Scheufler, Clemens, Marzinzik, Andreas, Brooijmans, Natasja, Glick, Meir
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Published in Journal of biomolecular screening (01.06.2015)
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Published in The Journal of biological chemistry (02.05.2003)
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Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide
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Published in Nature (London) (07.08.2014)
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JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors
Lorthiois, Edwige, Gerspacher, Marc, Beyer, Kim S., Vaupel, Andrea, Leblanc, Catherine, Stringer, Rowan, Weiss, Andreas, Wilcken, Rainer, Guthy, Daniel A., Lingel, Andreas, Bomio-Confaglia, Claudio, Machauer, Rainer, Rigollier, Pascal, Ottl, Johannes, Arz, Dorothee, Bernet, Pascal, Desjonqueres, Gaëlle, Dussauge, Solene, Kazic-Legueux, Malika, Lozac’h, Marie-Anne, Mura, Christophe, Sorge, Mickaël, Todorov, Milen, Warin, Nicolas, Zink, Florence, Voshol, Hans, Zecri, Frederic J., Sedrani, Richard C., Ostermann, Nils, Brachmann, Saskia M., Cotesta, Simona
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Weiss, Andreas, Lorthiois, Edwige, Barys, Louise, Beyer, Kim S, Bomio-Confaglia, Claudio, Burks, Heather, Chen, Xueying, Cui, Xiaoming, de Kanter, Ruben, Dharmarajan, Lekshmi, Fedele, Carmine, Gerspacher, Marc, Guthy, Daniel Alexander, Head, Victoria, Jaeger, Ashley, Núñez, Eloísa Jiménez, Kearns, Jeffrey D, Leblanc, Catherine, Maira, Sauveur-Michel, Murphy, Jason, Oakman, Helen, Ostermann, Nils, Ottl, Johannes, Rigollier, Pascal, Roman, Danielle, Schnell, Christian, Sedrani, Richard, Shimizu, Toshio, Stringer, Rowan, Vaupel, Andrea, Voshol, Hans, Wessels, Peter, Widmer, Toni, Wilcken, Rainer, Xu, Kun, Zecri, Frederic, Farago, Anna F, Cotesta, Simona, Brachmann, Saskia M
Published in Cancer discovery (02.06.2022)
Published in Cancer discovery (02.06.2022)
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Structure of lipoprotein lipase in complex with GPIHBP1
Arora, Rishi, Nimonkar, Amitabh V., Baird, Daniel, Wang, Chunhua, Chiu, Chun-Hao, Horton, Patricia A., Hanrahan, Susan, Cubbon, Rose, Weldon, Stephen, Tschantz, William R., Mueller, Sascha, Brunner, Reto, Lehr, Philipp, Meier, Peter, Ottl, Johannes, Voznesensky, Andrei, Pandey, Pramod, Smith, Thomas M., Stojanovic, Aleksandar, Flyer, Alec, Benson, Timothy E., Romanowski, Michael J., Trauger, John W.
Published in Proceedings of the National Academy of Sciences - PNAS (21.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (21.05.2019)
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Abstract 14275: Allosteric Inhibition Restricts Motion of the SMURF1 Glycine Hinge and Reverses Experimental Pulmonary Arterial Hypertension
Rothman, Alex M, Florentin, Amir, Quigley, Catherine, Zink, Florence, Bonneau, Olivier, Hemming, Rene, Hachey, Amanda, Rejtar, Tomas, Thaker, Maulik, Jain, Rishi, Zhang, Ji-Hu, Cotesta, Simona, Ottl, Johannes, Kordinsky, Alina, Avishid, Reut, Troxler, Thomas, Binmahfooz, Sarah K, Morrell, Nicholas W, Humbert, Marc, Cobb, Jennifer, Osterman, Nils, Tallerico, John, Shaw, Duncan, Guth-Gundel, Sabine, Prag, Gali, Rowlands, David J
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Published in Circulation (New York, N.Y.) (07.11.2023)
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Brousseau, Margaret E., Clairmont, Kevin B., Spraggon, Glen, Flyer, Alec N., Golosov, Andrei A., Grosche, Philipp, Amin, Jakal, Andre, Jerome, Burdick, Debra, Caplan, Shari, Chen, Guanjing, Chopra, Raj, Ames, Lisa, Dubiel, Diana, Fan, Li, Gattlen, Raphael, Kelly-Sullivan, Dawn, Koch, Alexander W., Lewis, Ian, Li, Jingzhou, Liu, Eugene, Lubicka, Danuta, Marzinzik, Andreas, Nakajima, Katsumasa, Nettleton, David, Ottl, Johannes, Pan, Meihui, Patel, Tajesh, Perry, Lauren, Pickett, Stephanie, Poirier, Jennifer, Reid, Patrick C., Pelle, Xavier, Seepersaud, Mohindra, Subramanian, Vanitha, Vera, Victoria, Xu, Mei, Yang, Lihua, Yang, Qing, Yu, Jinghua, Zhu, Guoming, Monovich, Lauren G.
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Published in Cell chemical biology (17.02.2022)
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Ding, Jian, Li, Guo, Liu, Hejun, Liu, Lulu, Lin, Ying, Gao, Jingyan, Zhou, Guoqiang, Shen, Lingling, Zhao, Mengxi, Yu, Yanyan, Guo, Weihui, Hommel, Ulrich, Ottl, Johannes, Blank, Jutta, Aubin, Nicola, Wei, Yi, He, Hu, Sage, David R., Atadja, Peter W., Li, En, Jain, Rishi K., Tallarico, John A., Canham, Stephen M., Chiang, Ying-Ling, Wang, He
Published in ACS chemical biology (20.01.2023)
Published in ACS chemical biology (20.01.2023)
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Biochemical and Structural Characterization of a Peptidic Inhibitor of the YAP:TEAD Interaction That Binds to the α‑Helix Pocket on TEAD
Mesrouze, Yannick, Gubler, Hanspeter, Villard, Frédéric, Boesch, Ralf, Ottl, Johannes, Kallen, Joerg, Reid, Patrick C., Scheufler, Clemens, Marzinzik, Andreas L., Chène, Patrick
Published in ACS chemical biology (17.03.2023)
Published in ACS chemical biology (17.03.2023)
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